7nra - Revision history

OCA at 12:38, 1 February 2024

OCA — Thu, 01 Feb 2024 12:38:36 GMT

←Older revision		Revision as of 12:38, 1 February 2024
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	<StructureSection load='7nra' size='340' side='right'caption='[[7nra]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='7nra' size='340' side='right'caption='[[7nra]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7nra]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NRA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7nra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sagittula_stellata_E-37 Sagittula stellata E-37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NRA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HCI:HYDROCINNAMIC+ACID'>HCI</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.91Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[7nqg\|7nqg]], [[7nr2\|7nr2]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCI:HYDROCINNAMIC+ACID'>HCI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nra OCA], [https://pdbe.org/7nra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nra RCSB], [https://www.ebi.ac.uk/pdbsum/7nra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nra ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nra OCA], [https://pdbe.org/7nra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nra RCSB], [https://www.ebi.ac.uk/pdbsum/7nra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nra ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A3K0X1_9RHOB A3K0X1_9RHOB]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bisson, C]]	+	[[Category: Sagittula stellata E-37]]
-	[[Category: Hitchcock, A]]	+	[[Category: Bisson C]]
-	[[Category: Kelly~~, D J~~]]	+	[[Category: Hitchcock A]]
-	[[Category: Rafferty~~, J B~~]]	+	[[Category: Kelly DJ]]
-	[[Category: Salmon~~, R C~~]]	+	[[Category: Rafferty JB]]
-	[[Category: Thomas~~, G H~~]]	+	[[Category: Salmon RC]]
-	[[Category: West, L]]	+	[[Category: Thomas GH]]
-	~~[[Category: Hydroxycinnamate]]~~	+	[[Category: West L]]
-	~~[[Category: Lignin]]~~	+
-	~~[[Category: Solute binding protein]]~~	+
-	~~[[Category: Transport protein]]~~	+
-	~~[[Category: Trap transporter~~]]	+

OCA at 07:10, 27 January 2022

OCA — Thu, 27 Jan 2022 07:10:09 GMT

←Older revision		Revision as of 07:10, 27 January 2022
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	==The structure of the SBP TarP_Sse in complex with cinnamate==		==The structure of the SBP TarP_Sse in complex with cinnamate==
-	<StructureSection load='7nra' size='340' side='right'caption='[[7nra]]' scene=''>	+	<StructureSection load='7nra' size='340' side='right'caption='[[7nra]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NRA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7nra]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NRA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nra OCA], [https://pdbe.org/7nra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nra RCSB], [https://www.ebi.ac.uk/pdbsum/7nra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nra ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCI:HYDROCINNAMIC+ACID'>HCI</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7nqg\|7nqg]], [[7nr2\|7nr2]]</div></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nra OCA], [https://pdbe.org/7nra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nra RCSB], [https://www.ebi.ac.uk/pdbsum/7nra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nra ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The organic polymer lignin is a component of plant cell walls, which like (hemi)-cellulose is highly abundant in nature and relatively resistant to degradation. However, extracellular enzymes released by natural microbial consortia can cleave the beta-aryl ether linkages in lignin, releasing monoaromatic phenylpropanoids that can be further catabolised by diverse species of bacteria. Biodegradation of lignin is therefore important in global carbon cycling, and its natural abundance also makes it an attractive biotechnological feedstock for the industrial production of commodity chemicals. Whilst the pathways for degradation of lignin-derived aromatics have been extensively characterised, much less is understood about how they are recognised and taken up from the environment. The purple phototrophic bacterium Rhodopseudomonas palustris can grow on a range of phenylpropanoid monomers and is a model organism for studying their uptake and breakdown. R. palustris encodes a tripartite ATP-independent periplasmic (TRAP) transporter (TarPQM) linked to genes encoding phenylpropanoid-degrading enzymes. The periplasmic solute-binding protein component of this transporter, TarP, has previously been shown to bind aromatic substrates. Here, we determine the high-resolution crystal structure of TarP from R. palustris as well as the structures of homologous proteins from the salt marsh bacterium Sagittula stellata and the halophile Chromohalobacter salexigens, which also grow on lignin-derived aromatics. In combination with tryptophan fluorescence ligand-binding assays, our ligand-bound co-crystal structures reveal the molecular basis for high-affinity recognition of phenylpropanoids by these TRAP transporters, which have potential for improving uptake of these compounds for biotechnological transformations of lignin.
		+
		+	The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.,Bisson C, Salmon RC, West L, Rafferty JB, Hitchcock A, Thomas GH, Kelly DJ FEBS J. 2021 Aug 10. doi: 10.1111/febs.16156. PMID:34375507<ref>PMID:34375507</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7nra" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bisson C]]	+	[[Category: Bisson, C]]
-	[[Category: Hitchcock A]]	+	[[Category: Hitchcock, A]]
-	[[Category: Kelly DJ]]	+	[[Category: Kelly, D J]]
-	[[Category: Rafferty JB]]	+	[[Category: Rafferty, J B]]
-	[[Category: Salmon RC]]	+	[[Category: Salmon, R C]]
-	[[Category: Thomas GH]]	+	[[Category: Thomas, G H]]
-	[[Category: West L]]	+	[[Category: West, L]]
		+	[[Category: Hydroxycinnamate]]
		+	[[Category: Lignin]]
		+	[[Category: Solute binding protein]]
		+	[[Category: Transport protein]]
		+	[[Category: Trap transporter]]

OCA at 05:32, 6 October 2021

OCA — Wed, 06 Oct 2021 05:32:22 GMT

←Older revision		Revision as of 05:32, 6 October 2021
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-	'''Unreleased structure'''

-	The ~~entry~~ 7nra is ~~ON HOLD until Paper Publication~~	+	==The structure of the SBP TarP_Sse in complex with cinnamate==
-		+	<StructureSection load='7nra' size='340' side='right'caption='[[7nra]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NRA FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nra OCA], [https://pdbe.org/7nra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nra RCSB], [https://www.ebi.ac.uk/pdbsum/7nra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nra ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Bisson C]]
		+	[[Category: Hitchcock A]]
		+	[[Category: Kelly DJ]]
		+	[[Category: Rafferty JB]]
		+	[[Category: Salmon RC]]
		+	[[Category: Thomas GH]]
		+	[[Category: West L]]

OCA at 04:44, 7 April 2021

OCA — Wed, 07 Apr 2021 04:44:41 GMT

←Older revision		Revision as of 04:44, 7 April 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7nra is ON HOLD	+	The entry 7nra is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7nra" [edit=sysop:move=sysop]

OCA — Wed, 10 Mar 2021 15:05:47 GMT

Protected "7nra" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:05, 10 March 2021

OCA: New page: '''Unreleased structure''' The entry 7nra is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 10 Mar 2021 15:05:45 GMT

New page: '''Unreleased structure''' The entry 7nra is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7nra is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]