7o4z - Revision history

OCA at 12:44, 1 February 2024

OCA — Thu, 01 Feb 2024 12:44:50 GMT

←Older revision		Revision as of 12:44, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='7o4z' size='340' side='right'caption='[[7o4z]], [[Resolution\|resolution]] 1.67Å' scene=''>		<StructureSection load='7o4z' size='340' side='right'caption='[[7o4z]], [[Resolution\|resolution]] 1.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7o4z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O4Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7o4z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_7942_=_FACHB-805 Synechococcus elongatus PCC 7942 = FACHB-805]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O4Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.67Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o4z OCA], [https://pdbe.org/7o4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o4z RCSB], [https://www.ebi.ac.uk/pdbsum/7o4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o4z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o4z OCA], [https://pdbe.org/7o4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o4z RCSB], [https://www.ebi.ac.uk/pdbsum/7o4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o4z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CCMM_SYNE7 CCMM_SYNE7]] The presence of two potential DNA-binding regions suggests this protein may be a transcriptional regulator.	+	[https://www.uniprot.org/uniprot/CCMM_SYNE7 CCMM_SYNE7] The presence of two potential DNA-binding regions suggests this protein may be a transcriptional regulator.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hartl~~, F U~~]]	+	[[Category: Synechococcus elongatus PCC 7942 = FACHB-805]]
-	[[Category: Hayer-Hartl, M]]	+	[[Category: Hartl FU]]
-	[[Category: Wang, H]]	+	[[Category: Hayer-Hartl M]]
-	[[Category: Zang, K]]	+	[[Category: Wang H]]
-	~~[[Category: Photosynthesis]]~~	+	[[Category: Zang K]]
-	~~[[Category: Protein binding carboxysome~~]]	+

OCA at 06:31, 1 December 2021

OCA — Wed, 01 Dec 2021 06:31:10 GMT

←Older revision		Revision as of 06:31, 1 December 2021
Line 1:		Line 1:

	==Crystal structure of the carbonic anhydrase-like domain of CcmM from Synechococcus elongatus (strain PCC 7942)==		==Crystal structure of the carbonic anhydrase-like domain of CcmM from Synechococcus elongatus (strain PCC 7942)==
-	<StructureSection load='7o4z' size='340' side='right'caption='[[7o4z]]' scene=''>	+	<StructureSection load='7o4z' size='340' side='right'caption='[[7o4z]], [[Resolution\|resolution]] 1.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O4Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7o4z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O4Z FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o4z OCA], [https://pdbe.org/7o4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o4z RCSB], [https://www.ebi.ac.uk/pdbsum/7o4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o4z ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o4z OCA], [https://pdbe.org/7o4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o4z RCSB], [https://www.ebi.ac.uk/pdbsum/7o4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o4z ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/CCMM_SYNE7 CCMM_SYNE7]] The presence of two potential DNA-binding regions suggests this protein may be a transcriptional regulator.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Carboxysomes in cyanobacteria enclose the enzymes Rubisco and carbonic anhydrase to optimize photosynthetic carbon fixation. Understanding carboxysome assembly has implications in agricultural biotechnology. Here we analyzed the role of the scaffolding protein CcmM of the beta-cyanobacterium Synechococcus elongatus PCC 7942 in sequestrating the hexadecameric Rubisco and the tetrameric carbonic anhydrase, CcaA. We find that the trimeric CcmM, consisting of gammaCAL oligomerization domains and linked small subunit-like (SSUL) modules, plays a central role in mediation of pre-carboxysome condensate formation through multivalent, cooperative interactions. The gammaCAL domains interact with the C-terminal tails of the CcaA subunits and additionally mediate a head-to-head association of CcmM trimers. Interestingly, SSUL modules, besides their known function in recruiting Rubisco, also participate in intermolecular interactions with the gammaCAL domains, providing further valency for network formation. Our findings reveal the mechanism by which CcmM functions as a central organizer of the pre-carboxysome multiprotein matrix, concentrating the core components Rubisco and CcaA before beta-carboxysome shell formation.
		+
		+	Scaffolding protein CcmM directs multiprotein phase separation in beta-carboxysome biogenesis.,Zang K, Wang H, Hartl FU, Hayer-Hartl M Nat Struct Mol Biol. 2021 Nov;28(11):909-922. doi: 10.1038/s41594-021-00676-5., Epub 2021 Nov 10. PMID:34759380<ref>PMID:34759380</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7o4z" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hartl FU]]	+	[[Category: Hartl, F U]]
-	[[Category: Hayer-Hartl M]]	+	[[Category: Hayer-Hartl, M]]
-	[[Category: Wang H]]	+	[[Category: Wang, H]]
-	[[Category: Zang K]]	+	[[Category: Zang, K]]
		+	[[Category: Photosynthesis]]
		+	[[Category: Protein binding carboxysome]]

OCA at 06:16, 10 November 2021

OCA — Wed, 10 Nov 2021 06:16:04 GMT

←Older revision		Revision as of 06:16, 10 November 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7o4z is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the carbonic anhydrase-like domain of CcmM from Synechococcus elongatus (strain PCC 7942)==
-		+	<StructureSection load='7o4z' size='340' side='right'caption='[[7o4z]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O4Z FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o4z OCA], [https://pdbe.org/7o4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o4z RCSB], [https://www.ebi.ac.uk/pdbsum/7o4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o4z ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Hartl FU]]
		+	[[Category: Hayer-Hartl M]]
		+	[[Category: Wang H]]
		+	[[Category: Zang K]]

OCA at 07:34, 5 May 2021

OCA — Wed, 05 May 2021 07:34:31 GMT

←Older revision		Revision as of 07:34, 5 May 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7o4z is ON HOLD	+	The entry 7o4z is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7o4z" [edit=sysop:move=sysop]

OCA — Wed, 14 Apr 2021 05:50:51 GMT

Protected "7o4z" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:50, 14 April 2021

OCA: New page: '''Unreleased structure''' The entry 7o4z is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 14 Apr 2021 05:50:50 GMT

New page: '''Unreleased structure''' The entry 7o4z is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7o4z is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]