7oa8 - Revision history

OCA at 12:48, 1 February 2024

OCA — Thu, 01 Feb 2024 12:48:06 GMT

←Older revision		Revision as of 12:48, 1 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7oa8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sanguinis Streptococcus sanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7oa8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sanguinis Streptococcus sanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa8 OCA], [https://pdbe.org/7oa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa8 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa8 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa8 OCA], [https://pdbe.org/7oa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa8 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 7oa8" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7oa8" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Pilin 3D structures\|Pilin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:40, 18 January 2023

OCA — Wed, 18 Jan 2023 07:40:42 GMT

←Older revision		Revision as of 07:40, 18 January 2023
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	==PilC minor pilin of Streptococcus sanguinis SK36 type IV pili==		==PilC minor pilin of Streptococcus sanguinis SK36 type IV pili==
-	<StructureSection load='7oa8' size='340' side='right'caption='[[7oa8]]' scene=''>	+	<StructureSection load='7oa8' size='340' side='right'caption='[[7oa8]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7oa8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sanguinis Streptococcus sanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA8 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa8 OCA], [https://pdbe.org/7oa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa8 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa8 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa8 OCA], [https://pdbe.org/7oa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa8 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A3R9NIL7_STRSA A0A3R9NIL7_STRSA] Required for transformation and DNA binding.[ARBA:ARBA00003988]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Type 4 filaments (T4F)-of which type 4 pili (T4P) are the archetype-are a superfamily of nanomachines nearly ubiquitous in prokaryotes. T4F are polymers of one major pilin, which also contain minor pilins whose roles are often poorly understood. Here, we complete the structure/function analysis of the full set of T4P pilins in the opportunistic bacterial pathogen Streptococcus sanguinis. We determined the structure of the minor pilin PilA, which is unexpectedly similar to one of the subunits of a tip-located complex of four minor pilins, widely conserved in T4F. We found that PilA interacts and dramatically stabilizes the minor pilin PilC. We determined the structure of PilC, showing that it is a modular pilin with a lectin module binding a subset of glycans prevalent in the human glycome, the host of S. sanguinis. Altogether, our findings support a model whereby the minor pilins in S. sanguinis T4P form a tip-located complex promoting adhesion to various host receptors. This has general implications for T4F.
		+
		+	Characterization of a glycan-binding complex of minor pilins completes the analysis of Streptococcus sanguinis type 4 pili subunits.,Shahin M, Sheppard D, Raynaud C, Berry JL, Gurung I, Silva LM, Feizi T, Liu Y, Pelicic V Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2216237120. doi: , 10.1073/pnas.2216237120. Epub 2023 Jan 10. PMID:36626560<ref>PMID:36626560</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7oa8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Streptococcus sanguinis]]
	[[Category: Pelicic V]]		[[Category: Pelicic V]]
	[[Category: Sheppard D]]		[[Category: Sheppard D]]

OCA at 12:47, 4 May 2022

OCA — Wed, 04 May 2022 12:47:44 GMT

←Older revision		Revision as of 12:47, 4 May 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7oa8 ~~is ON HOLD until Paper Publication~~	+	==PilC minor pilin of Streptococcus sanguinis SK36 type IV pili==
-		+	<StructureSection load='7oa8' size='340' side='right'caption='[[7oa8]]' scene=''>
-	~~Authors~~: ~~Sheppard~~, D., ~~Pelicic~~, V.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA8 FirstGlance]. <br>
-	~~Description: PilC minor pilin of Streptococcus sanguinis SK36 type IV pili~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa8 OCA], [https://pdbe.org/7oa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa8 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa8 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Sheppard, D~~]]	+	__TOC__
-	[[Category: ~~Pelicic, V~~]]	+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Pelicic V]]
		+	[[Category: Sheppard D]]

OCA at 09:03, 19 May 2021

OCA — Wed, 19 May 2021 09:03:20 GMT

←Older revision		Revision as of 09:03, 19 May 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7oa8 is ON HOLD	+	The entry 7oa8 is ON HOLD until Paper Publication

	Authors: Sheppard, D., Pelicic, V.		Authors: Sheppard, D., Pelicic, V.

OCA: Protected "7oa8" [edit=sysop:move=sysop]

OCA — Wed, 28 Apr 2021 04:26:45 GMT

Protected "7oa8" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:26, 28 April 2021

OCA: New page: '''Unreleased structure''' The entry 7oa8 is ON HOLD Authors: Sheppard, D., Pelicic, V. Description: PilC minor pilin of Streptococcus sanguinis SK36 type IV pili [[Category: Unrelease...

OCA — Wed, 28 Apr 2021 04:26:44 GMT

New page: '''Unreleased structure''' The entry 7oa8 is ON HOLD Authors: Sheppard, D., Pelicic, V. Description: PilC minor pilin of Streptococcus sanguinis SK36 type IV pili [[Category: Unrelease...

New page

'''Unreleased structure'''

The entry 7oa8 is ON HOLD

Authors: Sheppard, D., Pelicic, V.

Description: PilC minor pilin of Streptococcus sanguinis SK36 type IV pili
[[Category: Unreleased Structures]]
[[Category: Sheppard, D]]
[[Category: Pelicic, V]]