7oat - Revision history

OCA at 07:52, 7 February 2024

OCA — Wed, 07 Feb 2024 07:52:47 GMT

←Older revision		Revision as of 07:52, 7 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7oat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OAT FirstGlance]. <br>		<table><tr><td colspan='2'>[[7oat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OAT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.995Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oat OCA], [https://pdbe.org/7oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oat RCSB], [https://www.ebi.ac.uk/pdbsum/7oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oat ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oat OCA], [https://pdbe.org/7oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oat RCSB], [https://www.ebi.ac.uk/pdbsum/7oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oat ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:33, 15 February 2023

OCA — Wed, 15 Feb 2023 10:33:29 GMT

←Older revision		Revision as of 10:33, 15 February 2023
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	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN]] Translocation renal cell carcinoma;Alveolar soft-tissue sarcoma. A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.<ref>PMID:11244503</ref> A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).<ref>PMID:11358836</ref>	+	[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN] Translocation renal cell carcinoma;Alveolar soft-tissue sarcoma. A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.<ref>PMID:11244503</ref> A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).<ref>PMID:11358836</ref>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN]] Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT.<ref>PMID:23349634</ref>	+	[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN] Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT.<ref>PMID:23349634</ref>
	== References ==		== References ==
	<references/>		<references/>

OCA at 03:06, 8 September 2022

OCA — Thu, 08 Sep 2022 03:06:54 GMT

←Older revision		Revision as of 03:06, 8 September 2022
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-	====	+	==Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D==
-	<StructureSection load='7oat' size='340' side='right'caption='[[7oat]]' scene=''>	+	<StructureSection load='7oat' size='340' side='right'caption='[[7oat]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7oat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OAT FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oat OCA], [https://pdbe.org/7oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oat RCSB], [https://www.ebi.ac.uk/pdbsum/7oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oat ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oat OCA], [https://pdbe.org/7oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oat RCSB], [https://www.ebi.ac.uk/pdbsum/7oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oat ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN]] Translocation renal cell carcinoma;Alveolar soft-tissue sarcoma. A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.<ref>PMID:11244503</ref> A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).<ref>PMID:11358836</ref>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/ASPC1_HUMAN ASPC1_HUMAN]] Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT.<ref>PMID:23349634</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Heinemann U]]
		+	[[Category: Petrovic S]]
		+	[[Category: Roske Y]]

OCA at 04:50, 3 August 2022

OCA — Wed, 03 Aug 2022 04:50:38 GMT

←Older revision		Revision as of 04:50, 3 August 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7oat ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7oat' size='340' side='right'caption='[[7oat]]' scene=''>
-	~~Authors~~: ~~Petrovic, S~~.~~, Heinemann, U~~.~~, Roske, Y~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~: ~~Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oat OCA], [https://pdbe.org/7oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oat RCSB], [https://www.ebi.ac.uk/pdbsum/7oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oat ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Petrovic~~, S]]	+	__TOC__
-	[[Category: ~~Roske, Y~~]]	+	</StructureSection>
-	[[Category: ~~Heinemann, U~~]]	+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 13:43, 17 June 2021

OCA — Thu, 17 Jun 2021 13:43:51 GMT

←Older revision		Revision as of 13:43, 17 June 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7oat is ON HOLD	+	The entry 7oat is ON HOLD until Paper Publication

	Authors: Petrovic, S., Heinemann, U., Roske, Y.		Authors: Petrovic, S., Heinemann, U., Roske, Y.
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	Description: Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D		Description: Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Heinemann, U]]
	[[Category: Petrovic, S]]		[[Category: Petrovic, S]]
	[[Category: Roske, Y]]		[[Category: Roske, Y]]
		+	[[Category: Heinemann, U]]

OCA at 07:35, 5 May 2021

OCA — Wed, 05 May 2021 07:35:04 GMT

←Older revision		Revision as of 07:35, 5 May 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7oat is ON HOLD ~~until sometime in the future~~	+	The entry 7oat is ON HOLD

	Authors: Petrovic, S., Heinemann, U., Roske, Y.		Authors: Petrovic, S., Heinemann, U., Roske, Y.
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	Description: Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D		Description: Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Heinemann, U]]
	[[Category: Petrovic, S]]		[[Category: Petrovic, S]]
	[[Category: Roske, Y]]		[[Category: Roske, Y]]
-	[[Category: Heinemann, U]]

OCA: Protected "7oat" [edit=sysop:move=sysop]

OCA — Wed, 28 Apr 2021 04:27:37 GMT

Protected "7oat" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:27, 28 April 2021

OCA: New page: '''Unreleased structure''' The entry 7oat is ON HOLD until sometime in the future Authors: Petrovic, S., Heinemann, U., Roske, Y. Description: Structural basis for targeted p97 remodel...

OCA — Wed, 28 Apr 2021 04:27:36 GMT

New page: '''Unreleased structure''' The entry 7oat is ON HOLD until sometime in the future Authors: Petrovic, S., Heinemann, U., Roske, Y. Description: Structural basis for targeted p97 remodel...

New page

'''Unreleased structure'''

The entry 7oat is ON HOLD until sometime in the future

Authors: Petrovic, S., Heinemann, U., Roske, Y.

Description: Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
[[Category: Unreleased Structures]]
[[Category: Petrovic, S]]
[[Category: Roske, Y]]
[[Category: Heinemann, U]]