7odp - Revision history

OCA at 12:49, 1 February 2024

OCA — Thu, 01 Feb 2024 12:49:26 GMT

←Older revision		Revision as of 12:49, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='7odp' size='340' side='right'caption='[[7odp]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='7odp' size='340' side='right'caption='[[7odp]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7odp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ODP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ODP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7odp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ODP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ODP FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~CSO~~:~~S-HYDROXYCYSTEINE~~'>~~CSO~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Transaldolase Transaldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.2 2.2.1.2]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7odp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7odp OCA], [https://pdbe.org/7odp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7odp RCSB], [https://www.ebi.ac.uk/pdbsum/7odp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7odp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7odp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7odp OCA], [https://pdbe.org/7odp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7odp RCSB], [https://www.ebi.ac.uk/pdbsum/7odp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7odp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~A0A1D3FXY0_NEIGO A0A1D3FXY0_NEIGO]~~] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.~~[ARBA:ARBA00003518][HAMAP-Rule:MF_00493]~~	+	[https://www.uniprot.org/uniprot/TAL_NEIG1 TAL_NEIG1] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 7odp" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7odp" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Transaldolase 3D structures\|Transaldolase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Transaldolase~~]]	+	[[Category: Neisseria gonorrhoeae]]
-	[[Category: Pappenheim, F ~~Rabe von~~]]	+	[[Category: Rabe von Pappenheim F]]
-	[[Category: Tittmann, K]]	+	[[Category: Tittmann K]]
-	[[Category: Wensien, M]]	+	[[Category: Wensien M]]
-	~~[[Category: Cross-link]]~~	+
-	~~[[Category: Regulation]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:30, 2 March 2022

OCA — Wed, 02 Mar 2022 07:30:11 GMT

←Older revision		Revision as of 07:30, 2 March 2022
Line 1:		Line 1:

	==Neisseria gonorrhoeae transaldolase at 2.7 MGy dose==		==Neisseria gonorrhoeae transaldolase at 2.7 MGy dose==
-	<StructureSection load='7odp' size='340' side='right'caption='[[7odp]]' scene=''>	+	<StructureSection load='7odp' size='340' side='right'caption='[[7odp]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ODP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ODP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7odp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ODP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ODP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7odp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7odp OCA], [https://pdbe.org/7odp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7odp RCSB], [https://www.ebi.ac.uk/pdbsum/7odp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7odp ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transaldolase Transaldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.2 2.2.1.2] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7odp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7odp OCA], [https://pdbe.org/7odp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7odp RCSB], [https://www.ebi.ac.uk/pdbsum/7odp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7odp ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/A0A1D3FXY0_NEIGO A0A1D3FXY0_NEIGO]] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.[ARBA:ARBA00003518][HAMAP-Rule:MF_00493]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We recently reported the discovery of a lysine-cysteine redox switch in proteins with a covalent nitrogen-oxygen-sulfur (NOS) bridge. Here, a systematic survey of the whole protein structure database discloses that NOS bridges are ubiquitous redox switches in proteins of all domains of life and are found in diverse structural motifs and chemical variants. In several instances, lysines are observed in simultaneous linkage with two cysteines, forming a sulfur-oxygen-nitrogen-oxygen-sulfur (SONOS) bridge with a trivalent nitrogen, which constitutes an unusual native branching cross-link. In many proteins, the NOS switch contains a functionally essential lysine with direct roles in enzyme catalysis or binding of substrates, DNA or effectors, linking lysine chemistry and redox biology as a regulatory principle. NOS/SONOS switches are frequently found in proteins from human and plant pathogens, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and also in many human proteins with established roles in gene expression, redox signaling and homeostasis in physiological and pathophysiological conditions.
		+
		+	Widespread occurrence of covalent lysine-cysteine redox switches in proteins.,Rabe von Pappenheim F, Wensien M, Ye J, Uranga J, Irisarri I, de Vries J, Funk LM, Mata RA, Tittmann K Nat Chem Biol. 2022 Feb 14. pii: 10.1038/s41589-021-00966-5. doi:, 10.1038/s41589-021-00966-5. PMID:35165445<ref>PMID:35165445</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7odp" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Rabe von~~ Pappenheim F]]	+	[[Category: Transaldolase]]
-	[[Category: Tittmann K]]	+	[[Category: Pappenheim, F Rabe von]]
-	[[Category: Wensien M]]	+	[[Category: Tittmann, K]]
		+	[[Category: Wensien, M]]
		+	[[Category: Cross-link]]
		+	[[Category: Regulation]]
		+	[[Category: Transferase]]

OCA at 07:01, 2 February 2022

OCA — Wed, 02 Feb 2022 07:01:04 GMT

←Older revision		Revision as of 07:01, 2 February 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7odp ~~is ON HOLD until Paper Publication~~	+	==Neisseria gonorrhoeae transaldolase at 2.7 MGy dose==
-		+	<StructureSection load='7odp' size='340' side='right'caption='[[7odp]]' scene=''>
-	~~Authors~~: ~~Rabe von Pappenheim~~, F., ~~Wensien~~, M., ~~Tittmann~~, K.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ODP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ODP FirstGlance]. <br>
-	~~Description: Neisseria gonorrhoeae transaldolase at 2.7 MGy dose~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7odp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7odp OCA], [https://pdbe.org/7odp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7odp RCSB], [https://www.ebi.ac.uk/pdbsum/7odp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7odp ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Wensien, M~~]]	+	__TOC__
-	[[Category: Tittmann, K]]	+	</StructureSection>
-	[[Category: ~~Rabe Von Pappenheim, F~~]]	+	[[Category: Large Structures]]
		+	[[Category: Rabe von Pappenheim F]]
		+	[[Category: Tittmann K]]
		+	[[Category: Wensien M]]

OCA at 07:25, 8 September 2021

OCA — Wed, 08 Sep 2021 07:25:36 GMT

←Older revision		Revision as of 07:25, 8 September 2021
Line 5:		Line 5:
	Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K.		Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K.

-	Description: Neisseria gonorrhoeae transaldolase~~, 5~~ MGy dose	+	Description: Neisseria gonorrhoeae transaldolase at 2.7 MGy dose
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Wensien, M]]		[[Category: Wensien, M]]
	[[Category: Tittmann, K]]		[[Category: Tittmann, K]]
	[[Category: Rabe Von Pappenheim, F]]		[[Category: Rabe Von Pappenheim, F]]

OCA at 09:04, 19 May 2021

OCA — Wed, 19 May 2021 09:04:24 GMT

←Older revision		Revision as of 09:04, 19 May 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7odp is ON HOLD	+	The entry 7odp is ON HOLD until Paper Publication

	Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K.		Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K.
Line 7:		Line 7:
	Description: Neisseria gonorrhoeae transaldolase, 5 MGy dose		Description: Neisseria gonorrhoeae transaldolase, 5 MGy dose
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Tittmann, K]]
	[[Category: Wensien, M]]		[[Category: Wensien, M]]
		+	[[Category: Tittmann, K]]
	[[Category: Rabe Von Pappenheim, F]]		[[Category: Rabe Von Pappenheim, F]]

OCA: Protected "7odp" [edit=sysop:move=sysop]

OCA — Wed, 12 May 2021 08:22:22 GMT

Protected "7odp" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:22, 12 May 2021

OCA: New page: '''Unreleased structure''' The entry 7odp is ON HOLD Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K. Description: Neisseria gonorrhoeae transaldolase, 5 MGy dose [[Category...

OCA — Wed, 12 May 2021 08:22:21 GMT

New page: '''Unreleased structure''' The entry 7odp is ON HOLD Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K. Description: Neisseria gonorrhoeae transaldolase, 5 MGy dose [[Category...

New page

'''Unreleased structure'''

The entry 7odp is ON HOLD

Authors: Rabe von Pappenheim, F., Wensien, M., Tittmann, K.

Description: Neisseria gonorrhoeae transaldolase, 5 MGy dose
[[Category: Unreleased Structures]]
[[Category: Tittmann, K]]
[[Category: Wensien, M]]
[[Category: Rabe Von Pappenheim, F]]