7or5 - Revision history

OCA at 12:54, 1 February 2024

OCA — Thu, 01 Feb 2024 12:54:57 GMT

←Older revision		Revision as of 12:54, 1 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7or5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OR5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7or5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OR5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09W:~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-7-carboxamide'>09W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09W:~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-7-carboxamide'>09W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7or5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7or5 OCA], [https://pdbe.org/7or5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7or5 RCSB], [https://www.ebi.ac.uk/pdbsum/7or5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7or5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7or5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7or5 OCA], [https://pdbe.org/7or5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7or5 RCSB], [https://www.ebi.ac.uk/pdbsum/7or5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7or5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.	+	[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.

	==See Also==		==See Also==

OCA at 04:54, 8 September 2022

OCA — Thu, 08 Sep 2022 04:54:06 GMT

←Older revision		Revision as of 04:54, 8 September 2022
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-	====	+	==Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ162==
-	<StructureSection load='7or5' size='340' side='right'caption='[[7or5]]' scene=''>	+	<StructureSection load='7or5' size='340' side='right'caption='[[7or5]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7or5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OR5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7or5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7or5 OCA], [https://pdbe.org/7or5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7or5 RCSB], [https://www.ebi.ac.uk/pdbsum/7or5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7or5 ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09W:~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-7-carboxamide'>09W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7or5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7or5 OCA], [https://pdbe.org/7or5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7or5 RCSB], [https://www.ebi.ac.uk/pdbsum/7or5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7or5 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
		+
		+	==See Also==
		+	*[[14-3-3 protein 3D structures\|14-3-3 protein 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Centorrino F]]
		+	[[Category: Ottmann C]]
		+	[[Category: Wu Q]]

OCA at 06:47, 20 July 2022

OCA — Wed, 20 Jul 2022 06:47:37 GMT

←Older revision		Revision as of 06:47, 20 July 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7or5 ~~is ON HOLD until sometime in the future~~	+	====
-		+	<StructureSection load='7or5' size='340' side='right'caption='[[7or5]]' scene=''>
-	~~Authors~~: ~~Centorrino, F~~.~~, Wu, Q~~.~~, Ottmann, C~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~: ~~Ternary complex of 14~~-~~3-3 sigma~~, ~~NotchpS1917 phosphopeptide~~, ~~and WQ162~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7or5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7or5 OCA], [https://pdbe.org/7or5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7or5 RCSB], [https://www.ebi.ac.uk/pdbsum/7or5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7or5 ProSAT]</span></td></tr>
-	[~~[Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Ottmann~~, C]]	+	__TOC__
-	[[Category: ~~Centorrino, F~~]]	+	</StructureSection>
-	[[Category: ~~Wu, Q~~]]	+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 06:24, 22 June 2022

OCA — Wed, 22 Jun 2022 06:24:54 GMT

←Older revision		Revision as of 06:24, 22 June 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7or5 is ON HOLD until ~~Paper Publication~~	+	The entry 7or5 is ON HOLD until sometime in the future

	Authors: Centorrino, F., Wu, Q., Ottmann, C.		Authors: Centorrino, F., Wu, Q., Ottmann, C.

OCA at 08:49, 7 July 2021

OCA — Wed, 07 Jul 2021 08:49:08 GMT

←Older revision		Revision as of 08:49, 7 July 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7or5 is ON HOLD	+	The entry 7or5 is ON HOLD until Paper Publication

	Authors: Centorrino, F., Wu, Q., Ottmann, C.		Authors: Centorrino, F., Wu, Q., Ottmann, C.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Ottmann, C]]		[[Category: Ottmann, C]]
-	[[Category: Wu, Q]]
	[[Category: Centorrino, F]]		[[Category: Centorrino, F]]
		+	[[Category: Wu, Q]]

OCA: Protected "7or5" [edit=sysop:move=sysop]

OCA — Thu, 17 Jun 2021 13:49:41 GMT

Protected "7or5" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:49, 17 June 2021

OCA: New page: '''Unreleased structure''' The entry 7or5 is ON HOLD Authors: Centorrino, F., Wu, Q., Ottmann, C. Description: Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ162 [[...

OCA — Thu, 17 Jun 2021 13:49:40 GMT

New page: '''Unreleased structure''' The entry 7or5 is ON HOLD Authors: Centorrino, F., Wu, Q., Ottmann, C. Description: Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ162 [[...

New page

'''Unreleased structure'''

The entry 7or5 is ON HOLD

Authors: Centorrino, F., Wu, Q., Ottmann, C.

Description: Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ162
[[Category: Unreleased Structures]]
[[Category: Ottmann, C]]
[[Category: Wu, Q]]
[[Category: Centorrino, F]]