7orh - Revision history

OCA at 12:55, 1 February 2024

OCA — Thu, 01 Feb 2024 12:55:11 GMT

←Older revision		Revision as of 12:55, 1 February 2024
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-	====	+	==Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ178==
-	<StructureSection load='7orh' size='340' side='right'caption='[[7orh]]' scene=''>	+	<StructureSection load='7orh' size='340' side='right'caption='[[7orh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7orh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ORH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ORH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7orh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7orh OCA], [https://pdbe.org/7orh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7orh RCSB], [https://www.ebi.ac.uk/pdbsum/7orh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7orh ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0B7:~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-1~{H}-indole-6-carboxamide'>0B7</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7orh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7orh OCA], [https://pdbe.org/7orh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7orh RCSB], [https://www.ebi.ac.uk/pdbsum/7orh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7orh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
		+
		+	==See Also==
		+	*[[14-3-3 protein 3D structures\|14-3-3 protein 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Centorrino F]]
		+	[[Category: Ottmann C]]
		+	[[Category: Wu Q]]

OCA at 09:44, 22 June 2022

OCA — Wed, 22 Jun 2022 09:44:37 GMT

←Older revision		Revision as of 09:44, 22 June 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7orh ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7orh' size='340' side='right'caption='[[7orh]]' scene=''>
-	~~Authors~~: ~~Centorrino, F~~.~~, Wu, Q~~.~~, Ottmann, C~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~: ~~Ternary complex of 14~~-~~3-3 sigma~~, ~~p27pT198 phosphopeptide~~, ~~and WQ178~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7orh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7orh OCA], [https://pdbe.org/7orh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7orh RCSB], [https://www.ebi.ac.uk/pdbsum/7orh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7orh ProSAT]</span></td></tr>
-	[~~[Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[~~[Category~~: ~~Ottmann~~, C]]	+	__TOC__
-	[[Category: ~~Centorrino, F~~]]	+	</StructureSection>
-	[[Category: ~~Wu, Q~~]]	+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 08:49, 7 July 2021

OCA — Wed, 07 Jul 2021 08:49:23 GMT

←Older revision		Revision as of 08:49, 7 July 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7orh is ON HOLD	+	The entry 7orh is ON HOLD until Paper Publication

	Authors: Centorrino, F., Wu, Q., Ottmann, C.		Authors: Centorrino, F., Wu, Q., Ottmann, C.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Ottmann, C]]		[[Category: Ottmann, C]]
-	[[Category: Wu, Q]]
	[[Category: Centorrino, F]]		[[Category: Centorrino, F]]
		+	[[Category: Wu, Q]]

OCA: Protected "7orh" [edit=sysop:move=sysop]

OCA — Thu, 17 Jun 2021 13:50:14 GMT

Protected "7orh" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:50, 17 June 2021

OCA: New page: '''Unreleased structure''' The entry 7orh is ON HOLD Authors: Centorrino, F., Wu, Q., Ottmann, C. Description: Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ178 [[Cat...

OCA — Thu, 17 Jun 2021 13:50:13 GMT

New page: '''Unreleased structure''' The entry 7orh is ON HOLD Authors: Centorrino, F., Wu, Q., Ottmann, C. Description: Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ178 [[Cat...

New page

'''Unreleased structure'''

The entry 7orh is ON HOLD

Authors: Centorrino, F., Wu, Q., Ottmann, C.

Description: Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ178
[[Category: Unreleased Structures]]
[[Category: Ottmann, C]]
[[Category: Wu, Q]]
[[Category: Centorrino, F]]