7p9d - Revision history

OCA at 13:02, 1 February 2024

OCA — Thu, 01 Feb 2024 13:02:48 GMT

←Older revision		Revision as of 13:02, 1 February 2024
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	<StructureSection load='7p9d' size='340' side='right'caption='[[7p9d]], [[Resolution\|resolution]] 1.99Å' scene=''>		<StructureSection load='7p9d' size='340' side='right'caption='[[7p9d]], [[Resolution\|resolution]] 1.99Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7p9d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7p9d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9D FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FAD:FLAVIN~~-~~ADENINE+DINUCLEOTIDE'>FAD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.99Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9d OCA], [https://pdbe.org/7p9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9d RCSB], [https://www.ebi.ac.uk/pdbsum/7p9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9d OCA], [https://pdbe.org/7p9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9d RCSB], [https://www.ebi.ac.uk/pdbsum/7p9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9d ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A2K3E888_CHLRE A0A2K3E888_CHLRE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 7p9d" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7p9d" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Thioredoxin reductase 3D structures\|Thioredoxin reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chlamydomonas reinhardtii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Thioredoxin-disulfide reductase]]~~	+	[[Category: Hippler M]]
-	[[Category: Hippler, M]]	+	[[Category: Kuemmel D]]
-	[[Category: Kuemmel, D]]	+	[[Category: Marchetti GM]]
-	[[Category: Marchetti~~, G M~~]]	+	[[Category: Singh RK]]
-	[[Category: Singh~~, R K]]~~	+
-	~~[[Category: Fad binding domain]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 07:41, 19 January 2022

OCA — Wed, 19 Jan 2022 07:41:04 GMT

←Older revision		Revision as of 07:41, 19 January 2022
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	==Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain==		==Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain==
-	<StructureSection load='7p9d' size='340' side='right'caption='[[7p9d]]' scene=''>	+	<StructureSection load='7p9d' size='340' side='right'caption='[[7p9d]], [[Resolution\|resolution]] 1.99Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7p9d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9D FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9d OCA], [https://pdbe.org/7p9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9d RCSB], [https://www.ebi.ac.uk/pdbsum/7p9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9d ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9d OCA], [https://pdbe.org/7p9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9d RCSB], [https://www.ebi.ac.uk/pdbsum/7p9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9d ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In plant chloroplasts, thiol regulation is driven by two systems. One relies on the activity of thioredoxins through their light dependent reduction by ferredoxin via a ferredoxin-thioredoxin reductase (FTR). In the other system, a NADPH-dependent redox regulation is driven by a NADPH-thioredoxin reductase C (NTRC). While the thioredoxin system has been deeply studied, a more thorough understanding of the function of this plant specific NTRC is desirable. NTRC is a single polypeptide harbouring a thioredoxin domain (Trx) at the C-terminus of a NADPH-dependent Thioredoxin reductase (TrxR). To provide functional and structural insights, we studied the crystal structure of the TrxR domain of the NTRC from Chlamydomonas reinhardtii (CrNTRC, Cre01.g054150.t1.2) and its Cys136Ser (C136S) mutant, which is characterized by the mutation of the resolving cysteine in the active site of the TrxR domain. Furthermore, we confirmed the role of NTRC as electron donor for 2-Cys peroxiredoxin (PRX) also in C. reinhardtii. The structural data of TrxR were employed to develop a scheme of action which addresses electron transfer between TrxR and Trx of NTRC and between NTRC and its substrates.
		+
		+	Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.,Marchetti GM, Fusser F, Singh RK, Brummel M, Koch O, Kummel D, Hippler M J Struct Biol. 2021 Dec 30;214(1):107829. doi: 10.1016/j.jsb.2021.107829. PMID:34974142<ref>PMID:34974142</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7p9d" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hippler M]]	+	[[Category: Thioredoxin-disulfide reductase]]
-	[[Category: Kuemmel D]]	+	[[Category: Hippler, M]]
-	[[Category: Marchetti GM]]	+	[[Category: Kuemmel, D]]
-	[[Category: Singh RK]]	+	[[Category: Marchetti, G M]]
		+	[[Category: Singh, R K]]
		+	[[Category: Fad binding domain]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Oxidoreductase]]

OCA at 09:58, 12 January 2022

OCA — Wed, 12 Jan 2022 09:58:16 GMT

←Older revision		Revision as of 09:58, 12 January 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7p9d is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain==
-		+	<StructureSection load='7p9d' size='340' side='right'caption='[[7p9d]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9D FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9d OCA], [https://pdbe.org/7p9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9d RCSB], [https://www.ebi.ac.uk/pdbsum/7p9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9d ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Hippler M]]
		+	[[Category: Kuemmel D]]
		+	[[Category: Marchetti GM]]
		+	[[Category: Singh RK]]

OCA at 08:26, 8 December 2021

OCA — Wed, 08 Dec 2021 08:26:10 GMT

←Older revision		Revision as of 08:26, 8 December 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7p9d is ON HOLD	+	The entry 7p9d is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 12:38, 3 November 2021

OCA — Wed, 03 Nov 2021 12:38:16 GMT

←Older revision		Revision as of 12:38, 3 November 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7p9d is ON HOLD ~~until Paper Publication~~	+	The entry 7p9d is ON HOLD

	Authors:		Authors:

OCA at 05:09, 25 August 2021

OCA — Wed, 25 Aug 2021 05:09:27 GMT

←Older revision		Revision as of 05:09, 25 August 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7p9d is ON HOLD	+	The entry 7p9d is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7p9d" [edit=sysop:move=sysop]

OCA — Wed, 04 Aug 2021 09:15:01 GMT

Protected "7p9d" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:15, 4 August 2021

OCA: New page: '''Unreleased structure''' The entry 7p9d is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 04 Aug 2021 09:15:00 GMT

New page: '''Unreleased structure''' The entry 7p9d is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7p9d is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]