OCA at 08:30, 7 December 2022

OCA — Wed, 07 Dec 2022 08:30:12 GMT

←Older revision		Revision as of 08:30, 7 December 2022
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-	====	+	==Cryo-EM structure of light harvesting complex 2 from Rba. sphaeroides.==
-	<StructureSection load='7pbw' size='340' side='right'caption='[[7pbw]]' scene=''>	+	<StructureSection load='7pbw' size='340' side='right'caption='[[7pbw]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7pbw]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Cereibacter_sphaeroides_2.4.1 Cereibacter sphaeroides 2.4.1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PBW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pbw OCA], [https://pdbe.org/7pbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pbw RCSB], [https://www.ebi.ac.uk/pdbsum/7pbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pbw ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7OT:SPHEROIDENE'>7OT</scene>, <scene name='pdbligand=BCL:BACTERIOCHLOROPHYLL+A'>BCL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CXM:N-CARBOXYMETHIONINE'>CXM</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pbw OCA], [https://pdbe.org/7pbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pbw RCSB], [https://www.ebi.ac.uk/pdbsum/7pbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pbw ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LHA2_CERS4 LHA2_CERS4] Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Light-harvesting 2 (LH2) antenna complexes augment the collection of solar energy in many phototrophic bacteria. Despite its frequent role as a model for such complexes, there has been no three-dimensional (3D) structure available for the LH2 from the purple phototroph Rhodobacter sphaeroides. We used cryo-electron microscopy (cryo-EM) to determine the 2.1 A resolution structure of this LH2 antenna, which is a cylindrical assembly of nine alphabeta heterodimer subunits, each of which binds three bacteriochlorophyll a (BChl) molecules and one carotenoid. The high resolution of this structure reveals all of the interpigment and pigment-protein interactions that promote the assembly and energy-transfer properties of this complex. Near the cytoplasmic face of the complex there is a ring of nine BChls, which absorb maximally at 800 nm and are designated as B800; each B800 is coordinated by the N-terminal carboxymethionine of LH2-alpha, part of a network of interactions with nearby residues on both LH2-alpha and LH2-beta and with the carotenoid. Nine carotenoids, which are spheroidene in the strain we analyzed, snake through the complex, traversing the membrane and interacting with a ring of 18 BChls situated toward the periplasmic side of the complex. Hydrogen bonds with C-terminal aromatic residues modify the absorption of these pigments, which are red-shifted to 850 nm. Overlaps between the macrocycles of the B850 BChls ensure rapid transfer of excitation energy around this ring of pigments, which act as the donors of energy to neighboring LH2 and reaction center light-harvesting 1 (RC-LH1) complexes.
		+
		+	Cryo-EM Structure of the Rhodobacter sphaeroides Light-Harvesting 2 Complex at 2.1 A.,Qian P, Swainsbury DJK, Croll TI, Castro-Hartmann P, Divitini G, Sader K, Hunter CN Biochemistry. 2021 Nov 9;60(44):3302-3314. doi: 10.1021/acs.biochem.1c00576. Epub , 2021 Oct 26. PMID:34699186<ref>PMID:34699186</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7pbw" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cereibacter sphaeroides 2 4.1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Z-~~disk~~]]	+	[[Category: Castro-Hartmann P]]
		+	[[Category: Croll TI]]
		+	[[Category: Divitini G]]
		+	[[Category: Hunter CN]]
		+	[[Category: Qian P]]
		+	[[Category: Sader K]]
		+	[[Category: Swainsbury DJK]]

OCA at 12:37, 24 November 2021

OCA — Wed, 24 Nov 2021 12:37:11 GMT

←Older revision		Revision as of 12:37, 24 November 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7pbw ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7pbw' size='340' side='right'caption='[[7pbw]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pbw OCA], [https://pdbe.org/7pbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pbw RCSB], [https://www.ebi.ac.uk/pdbsum/7pbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pbw ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 08:08, 15 September 2021

OCA — Wed, 15 Sep 2021 08:08:13 GMT

←Older revision		Revision as of 08:08, 15 September 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7pbw is ON HOLD	+	The entry 7pbw is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7pbw" [edit=sysop:move=sysop]

OCA — Wed, 11 Aug 2021 05:05:21 GMT

Protected "7pbw" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:05, 11 August 2021

OCA: New page: '''Unreleased structure''' The entry 7pbw is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 11 Aug 2021 05:05:20 GMT

New page: '''Unreleased structure''' The entry 7pbw is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7pbw is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7pbw - Revision history

OCA at 08:30, 7 December 2022

OCA at 12:37, 24 November 2021

OCA at 08:08, 15 September 2021

OCA: Protected "7pbw" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7pbw is ON HOLD Authors: Description: Category: Unreleased Structures