7pq8 - Revision history

OCA at 13:07, 1 February 2024

OCA — Thu, 01 Feb 2024 13:07:43 GMT

←Older revision		Revision as of 13:07, 1 February 2024
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	<StructureSection load='7pq8' size='340' side='right'caption='[[7pq8]], [[Resolution\|resolution]] 1.33Å' scene=''>		<StructureSection load='7pq8' size='340' side='right'caption='[[7pq8]], [[Resolution\|resolution]] 1.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7pq8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PQ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7pq8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PQ8 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.329Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pq8 OCA], [https://pdbe.org/7pq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pq8 RCSB], [https://www.ebi.ac.uk/pdbsum/7pq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pq8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pq8 OCA], [https://pdbe.org/7pq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pq8 RCSB], [https://www.ebi.ac.uk/pdbsum/7pq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pq8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A1J6PBD5_CAMJU A0A1J6PBD5_CAMJU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Campylobacter jejuni]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Banas~~, A M~~]]	+	[[Category: Banas AM]]
-	[[Category: Bocian-Ostrzycka~~, K M~~]]	+	[[Category: Bocian-Ostrzycka KM]]
-	[[Category: Jagusztyn-Krynicka~~, E K~~]]	+	[[Category: Jagusztyn-Krynicka EK]]
-	[[Category: Orlikowska, M]]	+	[[Category: Orlikowska M]]
-	~~[[Category: Disulfide bond]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Periplasmic]]~~	+
-	~~[[Category: Posttranslational modification]]~~	+
-	~~[[Category: Thioredoxin fold~~]]	+

OCA at 10:46, 5 January 2022

OCA — Wed, 05 Jan 2022 10:46:03 GMT

←Older revision		Revision as of 10:46, 5 January 2022
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	==Crystal structure of Campylobacter jejuni DsbA1==		==Crystal structure of Campylobacter jejuni DsbA1==
-	<StructureSection load='7pq8' size='340' side='right'caption='[[7pq8]]' scene=''>	+	<StructureSection load='7pq8' size='340' side='right'caption='[[7pq8]], [[Resolution\|resolution]] 1.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PQ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7pq8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PQ8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pq8 OCA], [https://pdbe.org/7pq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pq8 RCSB], [https://www.ebi.ac.uk/pdbsum/7pq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pq8 ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pq8 OCA], [https://pdbe.org/7pq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pq8 RCSB], [https://www.ebi.ac.uk/pdbsum/7pq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pq8 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The bacterial proteins of the Dsb family catalyze the formation of disulfide bridges between cysteine residues that stabilize protein structures and ensure their proper functioning. Here, we report the detailed analysis of the Dsb pathway of Campylobacter jejuni. The oxidizing Dsb system of this pathogen is unique because it consists of two monomeric DsbAs (DsbA1 and DsbA2) and one dimeric bifunctional protein (C8J_1298). Previously, we showed that DsbA1 and C8J_1298 are redundant. Here, we unraveled the interaction between the two monomeric DsbAs by in vitro and in vivo experiments and by solving their structures and found that both monomeric DsbAs are dispensable proteins. Their structures confirmed that they are homologs of EcDsbL. The slight differences seen in the surface charge of the proteins do not affect the interaction with their redox partner. Comparative proteomics showed that several respiratory proteins, as well as periplasmic transport proteins, are targets of the Dsb system. Some of these, both donors and electron acceptors, are essential elements of the C. jejuni respiratory process under oxygen-limiting conditions in the host intestine. The data presented provide detailed information on the function of the C. jejuni Dsb system, identifying it as a potential target for novel antibacterial molecules.
		+
		+	Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis.,Banas AM, Bocian-Ostrzycka KM, Dunin-Horkawicz S, Ludwiczak J, Wilk P, Orlikowska M, Wyszynska A, Dabrowska M, Plichta M, Spodzieja M, Polanska MA, Malinowska A, Jagusztyn-Krynicka EK Int J Mol Sci. 2021 Dec 15;22(24). pii: ijms222413451. doi:, 10.3390/ijms222413451. PMID:34948248<ref>PMID:34948248</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7pq8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Banas AM]]	+	[[Category: Banas, A M]]
-	[[Category: Bocian-Ostrzycka KM]]	+	[[Category: Bocian-Ostrzycka, K M]]
-	[[Category: Jagusztyn-Krynicka EK]]	+	[[Category: Jagusztyn-Krynicka, E K]]
-	[[Category: Orlikowska M]]	+	[[Category: Orlikowska, M]]
		+	[[Category: Disulfide bond]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Periplasmic]]
		+	[[Category: Posttranslational modification]]
		+	[[Category: Thioredoxin fold]]

OCA at 14:10, 29 December 2021

OCA — Wed, 29 Dec 2021 14:10:43 GMT

←Older revision		Revision as of 14:10, 29 December 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7pq8 ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of Campylobacter jejuni DsbA1==
-		+	<StructureSection load='7pq8' size='340' side='right'caption='[[7pq8]]' scene=''>
-	~~Authors~~: ~~Orlikowska, M~~.~~, Bocian~~-~~Ostrzycka~~, K.M., ~~Banas~~, A.M., ~~Jagusztyn-Krynicka~~, E.K.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PQ8 FirstGlance]. <br>
-	~~Description: Crystal structure of Campylobacter jejuni DsbA1~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pq8 OCA], [https://pdbe.org/7pq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pq8 RCSB], [https://www.ebi.ac.uk/pdbsum/7pq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pq8 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Jagusztyn-Krynicka, E.K~~]]	+	__TOC__
-	[[Category: ~~Orlikowska, M~~]]	+	</StructureSection>
-	[[Category: ~~Banas, A.M~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Bocian-Ostrzycka, K.~~M]]	+	[[Category: Banas AM]]
		+	[[Category: Bocian-Ostrzycka KM]]
		+	[[Category: Jagusztyn-Krynicka EK]]
		+	[[Category: Orlikowska M]]

OCA at 04:05, 6 October 2021

OCA — Wed, 06 Oct 2021 04:05:42 GMT

←Older revision		Revision as of 04:05, 6 October 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7pq8 is ON HOLD	+	The entry 7pq8 is ON HOLD until Paper Publication

	Authors: Orlikowska, M., Bocian-Ostrzycka, K.M., Banas, A.M., Jagusztyn-Krynicka, E.K.		Authors: Orlikowska, M., Bocian-Ostrzycka, K.M., Banas, A.M., Jagusztyn-Krynicka, E.K.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Jagusztyn-Krynicka, E.K]]		[[Category: Jagusztyn-Krynicka, E.K]]
		+	[[Category: Orlikowska, M]]
	[[Category: Banas, A.M]]		[[Category: Banas, A.M]]
	[[Category: Bocian-Ostrzycka, K.M]]		[[Category: Bocian-Ostrzycka, K.M]]
-	[[Category: Orlikowska, M]]

OCA: Protected "7pq8" [edit=sysop:move=sysop]

OCA — Wed, 22 Sep 2021 05:33:13 GMT

Protected "7pq8" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:33, 22 September 2021

OCA: New page: '''Unreleased structure''' The entry 7pq8 is ON HOLD Authors: Orlikowska, M., Bocian-Ostrzycka, K.M., Banas, A.M., Jagusztyn-Krynicka, E.K. Description: Crystal structure of Campylobac...

OCA — Wed, 22 Sep 2021 05:33:11 GMT

New page: '''Unreleased structure''' The entry 7pq8 is ON HOLD Authors: Orlikowska, M., Bocian-Ostrzycka, K.M., Banas, A.M., Jagusztyn-Krynicka, E.K. Description: Crystal structure of Campylobac...

New page

'''Unreleased structure'''

The entry 7pq8 is ON HOLD

Authors: Orlikowska, M., Bocian-Ostrzycka, K.M., Banas, A.M., Jagusztyn-Krynicka, E.K.

Description: Crystal structure of Campylobacter jejuni DsbA1
[[Category: Unreleased Structures]]
[[Category: Jagusztyn-Krynicka, E.K]]
[[Category: Banas, A.M]]
[[Category: Bocian-Ostrzycka, K.M]]
[[Category: Orlikowska, M]]