7qa0 - Revision history

OCA at 13:15, 1 February 2024

OCA — Thu, 01 Feb 2024 13:15:47 GMT

←Older revision		Revision as of 13:15, 1 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7qa0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7qa0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QA0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ZL:~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine'>9ZL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.67Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ZL:~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine'>9ZL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qa0 OCA], [https://pdbe.org/7qa0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qa0 RCSB], [https://www.ebi.ac.uk/pdbsum/7qa0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qa0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qa0 OCA], [https://pdbe.org/7qa0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qa0 RCSB], [https://www.ebi.ac.uk/pdbsum/7qa0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qa0 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:00, 24 November 2022

OCA — Thu, 24 Nov 2022 10:00:42 GMT

←Older revision		Revision as of 10:00, 24 November 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7qa0 is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 1456==
-		+	<StructureSection load='7qa0' size='340' side='right'caption='[[7qa0]], [[Resolution\|resolution]] 2.67Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7qa0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QA0 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ZL:~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine'>9ZL</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qa0 OCA], [https://pdbe.org/7qa0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qa0 RCSB], [https://www.ebi.ac.uk/pdbsum/7qa0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qa0 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MVFR_PSEAE MVFR_PSEAE] Transcription regulator that plays a critical role in virulence by positively regulating the expression of multiple quorum sensing (QS)-regulated virulence factors, genes involved in protein secretion, translation, response to oxidative stress and the phnAB operon (PubMed:11724939, PubMed:27678057, PubMed:17083468). At the stationary phase, negatively autoregulates its function through cleavage and translocation to the extracellular space (PubMed:11724939).<ref>PMID:11724939</ref> <ref>PMID:17083468</ref> <ref>PMID:27678057</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Pseudomonas aeruginosa PAO1]]
		+	[[Category: Blankenfeldt W]]
		+	[[Category: Schmelz S]]

OCA at 11:46, 29 December 2021

OCA — Wed, 29 Dec 2021 11:46:53 GMT

←Older revision		Revision as of 11:46, 29 December 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7qa0 is ON HOLD	+	The entry 7qa0 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7qa0" [edit=sysop:move=sysop]

OCA — Wed, 24 Nov 2021 10:50:22 GMT

Protected "7qa0" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:50, 24 November 2021

OCA: New page: '''Unreleased structure''' The entry 7qa0 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 24 Nov 2021 10:50:20 GMT

New page: '''Unreleased structure''' The entry 7qa0 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7qa0 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]