7rvg - Revision history

OCA at 10:41, 22 May 2024

OCA — Wed, 22 May 2024 10:41:57 GMT

←Older revision		Revision as of 10:41, 22 May 2024
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	==Segment from rabbit/pig prion protein 168-176 QYSNQNSFV==		==Segment from rabbit/pig prion protein 168-176 QYSNQNSFV==
-	<StructureSection load='7rvg' size='340' side='right'caption='[[7rvg]]' scene=''>	+	<StructureSection load='7rvg' size='340' side='right'caption='[[7rvg]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RVG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7rvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RVG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rvg OCA], [https://pdbe.org/7rvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rvg RCSB], [https://www.ebi.ac.uk/pdbsum/7rvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rvg ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution\|Resolution]] 1Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rvg OCA], [https://pdbe.org/7rvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rvg RCSB], [https://www.ebi.ac.uk/pdbsum/7rvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rvg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/PRIO_RABIT PRIO_RABIT] Note=Found in high quantity in the brain of humans and animals infected with degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), etc.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PRIO_RABIT PRIO_RABIT] May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Oryctolagus cuniculus]]
	[[Category: Glynn C]]		[[Category: Glynn C]]
	[[Category: Hernandez E]]		[[Category: Hernandez E]]
	[[Category: Rodriguez JA]]		[[Category: Rodriguez JA]]

OCA at 04:48, 25 August 2022

OCA — Thu, 25 Aug 2022 04:48:45 GMT

←Older revision		Revision as of 04:48, 25 August 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7rvg is ~~ON HOLD until Paper Publication~~	+	==Segment from rabbit/pig prion protein 168-176 QYSNQNSFV==
-		+	<StructureSection load='7rvg' size='340' side='right'caption='[[7rvg]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RVG FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rvg OCA], [https://pdbe.org/7rvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rvg RCSB], [https://www.ebi.ac.uk/pdbsum/7rvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rvg ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Glynn C]]
		+	[[Category: Hernandez E]]
		+	[[Category: Rodriguez JA]]

OCA at 05:35, 22 September 2021

OCA — Wed, 22 Sep 2021 05:35:48 GMT

←Older revision		Revision as of 05:35, 22 September 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7rvg is ON HOLD	+	The entry 7rvg is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7rvg" [edit=sysop:move=sysop]

OCA — Wed, 25 Aug 2021 05:20:16 GMT

Protected "7rvg" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:20, 25 August 2021

OCA: New page: '''Unreleased structure''' The entry 7rvg is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 25 Aug 2021 05:20:15 GMT

New page: '''Unreleased structure''' The entry 7rvg is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7rvg is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]