7sgj - Revision history

OCA at 16:51, 18 October 2023

OCA — Wed, 18 Oct 2023 16:51:02 GMT

←Older revision		Revision as of 16:51, 18 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7sgj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SGJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[7sgj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SGJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9BI:4-[(3-anilino-3-oxopropyl)(methyl)amino]-N-hydroxybutanamide'>9BI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9BI:4-[(3-anilino-3-oxopropyl)(methyl)amino]-N-hydroxybutanamide'>9BI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sgj OCA], [https://pdbe.org/7sgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sgj RCSB], [https://www.ebi.ac.uk/pdbsum/7sgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sgj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sgj OCA], [https://pdbe.org/7sgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sgj RCSB], [https://www.ebi.ac.uk/pdbsum/7sgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sgj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/HDA10_DANRE HDA10_DANRE] Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine (PubMed:28516954). Has a very weak lysine deacetylase, if any (PubMed:28516954).<ref>PMID:28516954</ref>		[https://www.uniprot.org/uniprot/HDA10_DANRE HDA10_DANRE] Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine (PubMed:28516954). Has a very weak lysine deacetylase, if any (PubMed:28516954).<ref>PMID:28516954</ref>
		+
		+	==See Also==
		+	*[[Histone deacetylase 3D structures\|Histone deacetylase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:32, 19 October 2022

OCA — Wed, 19 Oct 2022 19:32:15 GMT

←Older revision		Revision as of 19:32, 19 October 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7sgj is ~~ON HOLD until Paper Publication~~	+	==Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711==
-		+	<StructureSection load='7sgj' size='340' side='right'caption='[[7sgj]], [[Resolution\|resolution]] 2.15Å' scene=''>
-	~~Authors~~: ~~Herbst~~-~~Gervasoni~~, C.J., ~~Christianson~~, D.W.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7sgj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SGJ FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure of~~ Danio rerio ~~Histone Deacetylase 10 in Complex with DKFZ-711~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9BI:4-[(3-anilino-3-oxopropyl)(methyl)amino]-N-hydroxybutanamide'>9BI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sgj OCA], [https://pdbe.org/7sgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sgj RCSB], [https://www.ebi.ac.uk/pdbsum/7sgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sgj ProSAT]</span></td></tr>
-	[[Category: ~~Herbst-Gervasoni, C.J~~]]	+	</table>
-	[[Category: ~~Christianson, D.W~~]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/HDA10_DANRE HDA10_DANRE] Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine (PubMed:28516954). Has a very weak lysine deacetylase, if any (PubMed:28516954).<ref>PMID:28516954</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Danio rerio]]
		+	[[Category: Large Structures]]
		+	[[Category: Christianson DW]]
		+	[[Category: Herbst-Gervasoni CJ]]

OCA at 05:15, 10 November 2021

OCA — Wed, 10 Nov 2021 05:15:11 GMT

←Older revision		Revision as of 05:15, 10 November 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7sgj is ON HOLD	+	The entry 7sgj is ON HOLD until Paper Publication

	Authors: Herbst-Gervasoni, C.J., Christianson, D.W.		Authors: Herbst-Gervasoni, C.J., Christianson, D.W.
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	Description: Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711		Description: Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Christianson, D.W]]
	[[Category: Herbst-Gervasoni, C.J]]		[[Category: Herbst-Gervasoni, C.J]]
		+	[[Category: Christianson, D.W]]

OCA: Protected "7sgj" [edit=sysop:move=sysop]

OCA — Wed, 13 Oct 2021 10:28:50 GMT

Protected "7sgj" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:28, 13 October 2021

OCA: New page: '''Unreleased structure''' The entry 7sgj is ON HOLD Authors: Herbst-Gervasoni, C.J., Christianson, D.W. Description: Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex...

OCA — Wed, 13 Oct 2021 10:28:48 GMT

New page: '''Unreleased structure''' The entry 7sgj is ON HOLD Authors: Herbst-Gervasoni, C.J., Christianson, D.W. Description: Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex...

New page

'''Unreleased structure'''

The entry 7sgj is ON HOLD

Authors: Herbst-Gervasoni, C.J., Christianson, D.W.

Description: Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711
[[Category: Unreleased Structures]]
[[Category: Christianson, D.W]]
[[Category: Herbst-Gervasoni, C.J]]