7sqt - Revision history

OCA at 04:15, 8 September 2022

OCA — Thu, 08 Sep 2022 04:15:38 GMT

←Older revision		Revision as of 04:15, 8 September 2022
Line 1:		Line 1:

	==Goslar chimallin cubic (O, 24mer) assembly==		==Goslar chimallin cubic (O, 24mer) assembly==
-	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]]' scene=''>	+	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]], [[Resolution\|resolution]] 4.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7sqt]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_vB_EcoM_Goslar Escherichia phage vB_EcoM_Goslar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/A0A482GDX1_9CAUD A0A482GDX1_9CAUD]]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacteria encode myriad defences that target the genomes of infecting bacteriophage, including restriction-modification and CRISPR-Cas systems(1). In response, one family of large bacteriophages uses a nucleus-like compartment to protect its replicating genomes by excluding host defence factors(2-4). However, the principal composition and structure of this compartment remain unknown. Here we find that the bacteriophage nuclear shell assembles primarily from one protein, which we name chimallin (ChmA). Combining cryo-electron tomography of nuclear shells in bacteriophage-infected cells and cryo-electron microscopy of a minimal chimallin compartment in vitro, we show that chimallin self-assembles as a flexible sheet into closed micrometre-scale compartments. The architecture and assembly dynamics of the chimallin shell suggest mechanisms for its nucleation and growth, and its role as a scaffold for phage-encoded factors mediating macromolecular transport, cytoskeletal interactions, and viral maturation.
		+
		+	Architecture and self-assembly of the jumbo bacteriophage nuclear shell.,Laughlin TG, Deep A, Prichard AM, Seitz C, Gu Y, Enustun E, Suslov S, Khanna K, Birkholz EA, Armbruster E, McCammon JA, Amaro RE, Pogliano J, Corbett KD, Villa E Nature. 2022 Aug;608(7922):429-435. doi: 10.1038/s41586-022-05013-4. Epub 2022, Aug 3. PMID:35922510<ref>PMID:35922510</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7sqt" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia phage vB_EcoM_Goslar]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Amaro RE]]		[[Category: Amaro RE]]

OCA at 11:08, 31 August 2022

OCA — Wed, 31 Aug 2022 11:08:03 GMT

←Older revision		Revision as of 11:08, 31 August 2022
Line 1:		Line 1:

	==Goslar chimallin cubic (O, 24mer) assembly==		==Goslar chimallin cubic (O, 24mer) assembly==
-	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]]~~, [[Resolution\|resolution]] 4.00Å~~' scene=''>	+	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[7sqt]] is a 24 chain structure.~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Bacteria encode myriad defences that target the genomes of infecting bacteriophage, including restriction-modification and CRISPR-Cas systems(1). In response, one family of large bacteriophages uses a nucleus-like compartment to protect its replicating genomes by excluding host defence factors(2-4). However, the principal composition and structure of this compartment remain unknown. Here we find that the bacteriophage nuclear shell assembles primarily from one protein, which we name chimallin (ChmA). Combining cryo-electron tomography of nuclear shells in bacteriophage-infected cells and cryo-electron microscopy of a minimal chimallin compartment in vitro, we show that chimallin self-assembles as a flexible sheet into closed micrometre-scale compartments. The architecture and assembly dynamics of the chimallin shell suggest mechanisms for its nucleation and growth, and its role as a scaffold for phage-encoded factors mediating macromolecular transport, cytoskeletal interactions, and viral maturation.
-
-	Architecture and self-assembly of the jumbo bacteriophage nuclear shell.,Laughlin TG, Deep A, Prichard AM, Seitz C, Gu Y, Enustun E, Suslov S, Khanna K, Birkholz EA, Armbruster E, McCammon JA, Amaro RE, Pogliano J, Corbett KD, Villa E Nature. 2022 Aug;608(7922):429-435. doi: 10.1038/s41586-022-05013-4. Epub 2022, Aug 3. PMID:35922510<ref>PMID:35922510</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 7sqt" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Amaro~~, R E~~]]	+	[[Category: Amaro RE]]
-	[[Category: Birkholz~~, E A~~]]	+	[[Category: Birkholz EA]]
-	[[Category: Corbett~~, K D~~]]	+	[[Category: Corbett KD]]
-	[[Category: Deep, A]]	+	[[Category: Deep A]]
-	[[Category: Enustun, E]]	+	[[Category: Enustun E]]
-	[[Category: Gu, Y]]	+	[[Category: Gu Y]]
-	[[Category: Khanna, K]]	+	[[Category: Khanna K]]
-	[[Category: Laughlin~~, T G~~]]	+	[[Category: Laughlin TG]]
-	[[Category: Pogliano, J]]	+	[[Category: Pogliano J]]
-	[[Category: Prichard~~, A M~~]]	+	[[Category: Prichard AM]]
-	[[Category: Seitz, C]]	+	[[Category: Seitz C]]
-	[[Category: Suslov, S]]	+	[[Category: Suslov S]]
-	[[Category: Villa, E]]	+	[[Category: Villa E]]
-	~~[[Category: Phage]]~~	+
-	~~[[Category: Structural protein]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 06:40, 18 August 2022

OCA — Thu, 18 Aug 2022 06:40:59 GMT

←Older revision		Revision as of 06:40, 18 August 2022
Line 1:		Line 1:

	==Goslar chimallin cubic (O, 24mer) assembly==		==Goslar chimallin cubic (O, 24mer) assembly==
-	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]]' scene=''>	+	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]], [[Resolution\|resolution]] 4.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7sqt]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacteria encode myriad defences that target the genomes of infecting bacteriophage, including restriction-modification and CRISPR-Cas systems(1). In response, one family of large bacteriophages uses a nucleus-like compartment to protect its replicating genomes by excluding host defence factors(2-4). However, the principal composition and structure of this compartment remain unknown. Here we find that the bacteriophage nuclear shell assembles primarily from one protein, which we name chimallin (ChmA). Combining cryo-electron tomography of nuclear shells in bacteriophage-infected cells and cryo-electron microscopy of a minimal chimallin compartment in vitro, we show that chimallin self-assembles as a flexible sheet into closed micrometre-scale compartments. The architecture and assembly dynamics of the chimallin shell suggest mechanisms for its nucleation and growth, and its role as a scaffold for phage-encoded factors mediating macromolecular transport, cytoskeletal interactions, and viral maturation.
		+
		+	Architecture and self-assembly of the jumbo bacteriophage nuclear shell.,Laughlin TG, Deep A, Prichard AM, Seitz C, Gu Y, Enustun E, Suslov S, Khanna K, Birkholz EA, Armbruster E, McCammon JA, Amaro RE, Pogliano J, Corbett KD, Villa E Nature. 2022 Aug;608(7922):429-435. doi: 10.1038/s41586-022-05013-4. Epub 2022, Aug 3. PMID:35922510<ref>PMID:35922510</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7sqt" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Amaro RE]]	+	[[Category: Amaro, R E]]
-	[[Category: Birkholz EA]]	+	[[Category: Birkholz, E A]]
-	[[Category: Corbett KD]]	+	[[Category: Corbett, K D]]
-	[[Category: Deep A]]	+	[[Category: Deep, A]]
-	[[Category: Enustun E]]	+	[[Category: Enustun, E]]
-	[[Category: Gu Y]]	+	[[Category: Gu, Y]]
-	[[Category: Khanna K]]	+	[[Category: Khanna, K]]
-	[[Category: Laughlin TG]]	+	[[Category: Laughlin, T G]]
-	[[Category: Pogliano J]]	+	[[Category: Pogliano, J]]
-	[[Category: Prichard AM]]	+	[[Category: Prichard, A M]]
-	[[Category: Seitz C]]	+	[[Category: Seitz, C]]
-	[[Category: Suslov S]]	+	[[Category: Suslov, S]]
-	[[Category: Villa E]]	+	[[Category: Villa, E]]
		+	[[Category: Phage]]
		+	[[Category: Structural protein]]
		+	[[Category: Viral protein]]

OCA at 18:04, 27 July 2022

OCA — Wed, 27 Jul 2022 18:04:11 GMT

←Older revision		Revision as of 18:04, 27 July 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7sqt is ~~ON HOLD until Paper Publication~~	+	==Goslar chimallin cubic (O, 24mer) assembly==
-		+	<StructureSection load='7sqt' size='340' side='right'caption='[[7sqt]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQT FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqt OCA], [https://pdbe.org/7sqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqt RCSB], [https://www.ebi.ac.uk/pdbsum/7sqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqt ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Amaro RE]]
		+	[[Category: Birkholz EA]]
		+	[[Category: Corbett KD]]
		+	[[Category: Deep A]]
		+	[[Category: Enustun E]]
		+	[[Category: Gu Y]]
		+	[[Category: Khanna K]]
		+	[[Category: Laughlin TG]]
		+	[[Category: Pogliano J]]
		+	[[Category: Prichard AM]]
		+	[[Category: Seitz C]]
		+	[[Category: Suslov S]]
		+	[[Category: Villa E]]

OCA at 15:38, 15 December 2021

OCA — Wed, 15 Dec 2021 15:38:34 GMT

←Older revision		Revision as of 15:38, 15 December 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7sqt is ON HOLD	+	The entry 7sqt is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7sqt" [edit=sysop:move=sysop]

OCA — Wed, 17 Nov 2021 12:13:35 GMT

Protected "7sqt" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:13, 17 November 2021

OCA: New page: '''Unreleased structure''' The entry 7sqt is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 17 Nov 2021 12:13:34 GMT

New page: '''Unreleased structure''' The entry 7sqt is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7sqt is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]