7tib - Revision history

OCA at 13:08, 1 March 2024

OCA — Fri, 01 Mar 2024 13:08:36 GMT

←Older revision		Revision as of 13:08, 1 March 2024
Line 1:		Line 1:

-	====	+	==Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA==
-	<StructureSection load='7tib' size='340' side='right'caption='[[7tib]]' scene=''>	+	<StructureSection load='7tib' size='340' side='right'caption='[[7tib]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7tib]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TIB FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tib OCA], [https://pdbe.org/7tib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tib RCSB], [https://www.ebi.ac.uk/pdbsum/7tib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tib ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tib OCA], [https://pdbe.org/7tib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tib RCSB], [https://www.ebi.ac.uk/pdbsum/7tib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tib ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RFC1_YEAST RFC1_YEAST] Component of the ATP-dependent clamp loader RFC complex for the POL30/PCNA homotrimer DNA clamp. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Replication factor C (RFC or activator 1) complex acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment.
		+
		+	==See Also==
		+	*[[Proliferating cell nuclear antigen 3D structures\|Proliferating cell nuclear antigen 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Saccharomyces cerevisiae]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Demo G]]
		+	[[Category: Gaubitz C]]
		+	[[Category: Hayes J]]
		+	[[Category: Kelch BA]]
		+	[[Category: Liu X]]
		+	[[Category: Pajak J]]
		+	[[Category: Stone N]]

OCA at 10:18, 16 February 2022

OCA — Wed, 16 Feb 2022 10:18:42 GMT

←Older revision		Revision as of 10:18, 16 February 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7tib ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7tib' size='340' side='right'caption='[[7tib]]' scene=''>
-	~~Authors~~: ~~Gaubitz, C~~.~~, Liu, X~~.~~, Pajak, J~~.~~, Stone, N~~.~~, Hayes, J~~.~~, Demo, G~~.~~, Kelch, B.A~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~: ~~Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tib OCA], [https://pdbe.org/7tib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tib RCSB], [https://www.ebi.ac.uk/pdbsum/7tib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tib ProSAT]</span></td></tr>
-	[~~[Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[~~[Category~~: ~~Stone~~, ~~N]]~~	+	__TOC__
-	[~~[Category~~: ~~Demo, G~~]]	+	</StructureSection>
-	[~~[Category~~: ~~Pajak~~, ~~J]]~~	+	[[Category: Large Structures]]
-	[~~[Category~~: ~~Hayes~~, ~~J]]~~	+	[[Category: Z-disk]]
-	[~~[Category~~: ~~Liu, X]~~]	+
-	[[Category: ~~Gaubitz, C~~]]	+
-	[[Category: ~~Kelch, B.A~~]]	+

OCA: Protected "7tib" [edit=sysop:move=sysop]

OCA — Wed, 19 Jan 2022 06:05:53 GMT

Protected "7tib" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:05, 19 January 2022

OCA: New page: '''Unreleased structure''' The entry 7tib is ON HOLD Authors: Gaubitz, C., Liu, X., Pajak, J., Stone, N., Hayes, J., Demo, G., Kelch, B.A. Description: Structure of the yeast clamp loa...

OCA — Wed, 19 Jan 2022 06:05:52 GMT

New page: '''Unreleased structure''' The entry 7tib is ON HOLD Authors: Gaubitz, C., Liu, X., Pajak, J., Stone, N., Hayes, J., Demo, G., Kelch, B.A. Description: Structure of the yeast clamp loa...

New page

'''Unreleased structure'''

The entry 7tib is ON HOLD

Authors: Gaubitz, C., Liu, X., Pajak, J., Stone, N., Hayes, J., Demo, G., Kelch, B.A.

Description: Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA
[[Category: Unreleased Structures]]
[[Category: Stone, N]]
[[Category: Demo, G]]
[[Category: Pajak, J]]
[[Category: Hayes, J]]
[[Category: Liu, X]]
[[Category: Gaubitz, C]]
[[Category: Kelch, B.A]]