OCA at 10:55, 21 February 2024

OCA — Wed, 21 Feb 2024 10:55:57 GMT

←Older revision		Revision as of 10:55, 21 February 2024
Line 1:		Line 1:

-	====	+	==E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20==
-	<StructureSection load='7tos' size='340' side='right'caption='[[7tos]]' scene=''>	+	<StructureSection load='7tos' size='340' side='right'caption='[[7tos]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7tos]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TOS FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tos OCA], [https://pdbe.org/7tos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tos RCSB], [https://www.ebi.ac.uk/pdbsum/7tos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tos ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tos OCA], [https://pdbe.org/7tos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tos RCSB], [https://www.ebi.ac.uk/pdbsum/7tos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tos ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RL4_ECOLI RL4_ECOLI] One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.<ref>PMID:2442760</ref> Protein L4 is a both a transcriptional repressor and a translational repressor protein; these two functions are independent of each other. It regulates transcription of the S10 operon (to which L4 belongs) by causing premature termination of transcription within the S10 leader; termination absolutely requires the NusA protein. L4 controls the translation of the S10 operon by binding to its mRNA. The regions of L4 that control regulation (residues 131-210) are different from those required for ribosome assembly (residues 89-103).<ref>PMID:2442760</ref> Forms part of the polypeptide exit tunnel.<ref>PMID:2442760</ref> Can regulate expression from Citrobacter freundii, Haemophilus influenzae, Morganella morganii, Salmonella typhimurium, Serratia marcescens, Vibrio cholerae and Yersinia enterocolitica (but not Pseudomonas aeruginosa) S10 leaders in vitro.<ref>PMID:2442760</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Demo G]]
		+	[[Category: Gao FB]]
		+	[[Category: Korostelev AA]]
		+	[[Category: Lee S]]
		+	[[Category: Loveland AB]]
		+	[[Category: Park A]]
		+	[[Category: Susorov D]]
		+	[[Category: Svidritskiy E]]
		+	[[Category: Zvornicanin S]]

OCA at 07:59, 25 May 2022

OCA — Wed, 25 May 2022 07:59:33 GMT

←Older revision		Revision as of 07:59, 25 May 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7tos ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7tos' size='340' side='right'caption='[[7tos]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tos OCA], [https://pdbe.org/7tos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tos RCSB], [https://www.ebi.ac.uk/pdbsum/7tos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tos ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA: Protected "7tos" [edit=sysop:move=sysop]

OCA — Wed, 02 Feb 2022 05:39:33 GMT

Protected "7tos" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:39, 2 February 2022

OCA: New page: '''Unreleased structure''' The entry 7tos is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 02 Feb 2022 05:39:32 GMT

New page: '''Unreleased structure''' The entry 7tos is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7tos is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7tos - Revision history

OCA at 10:55, 21 February 2024

OCA at 07:59, 25 May 2022

OCA: Protected "7tos" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7tos is ON HOLD Authors: Description: Category: Unreleased Structures