7txt - Revision history

OCA at 10:54, 27 March 2024

OCA — Wed, 27 Mar 2024 10:54:41 GMT

←Older revision		Revision as of 10:54, 27 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7txt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TXT FirstGlance]. <br>		<table><tr><td colspan='2'>[[7txt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TXT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KWC:1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine'>KWC</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KWC:1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine'>KWC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7txt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7txt OCA], [https://pdbe.org/7txt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7txt RCSB], [https://www.ebi.ac.uk/pdbsum/7txt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7txt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7txt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7txt OCA], [https://pdbe.org/7txt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7txt RCSB], [https://www.ebi.ac.uk/pdbsum/7txt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7txt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/SC6A4_HUMAN SC6A4_HUMAN] Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.<ref>PMID:17506858</ref> <ref>PMID:18227069</ref> <ref>PMID:19270731</ref>		[https://www.uniprot.org/uniprot/SC6A4_HUMAN SC6A4_HUMAN] Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.<ref>PMID:17506858</ref> <ref>PMID:18227069</ref> <ref>PMID:19270731</ref>
		+
		+	==See Also==
		+	*[[Serotonin Transporter\|Serotonin Transporter]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:47, 15 March 2023

OCA — Wed, 15 Mar 2023 09:47:16 GMT

←Older revision		Revision as of 09:47, 15 March 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7txt is ~~ON HOLD until Paper Publication~~	+	==Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl==
-		+	<StructureSection load='7txt' size='340' side='right'caption='[[7txt]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7txt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TXT FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KWC:1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine'>KWC</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7txt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7txt OCA], [https://pdbe.org/7txt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7txt RCSB], [https://www.ebi.ac.uk/pdbsum/7txt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7txt ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SC6A4_HUMAN SC6A4_HUMAN] Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.<ref>PMID:17506858</ref> <ref>PMID:18227069</ref> <ref>PMID:19270731</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Mus musculus]]
		+	[[Category: Basbaum AI]]
		+	[[Category: Bekele B]]
		+	[[Category: Billesboelle CB]]
		+	[[Category: Boytsov D]]
		+	[[Category: Braz J]]
		+	[[Category: Craik V]]
		+	[[Category: Huang XP]]
		+	[[Category: Lak P]]
		+	[[Category: Manglik A]]
		+	[[Category: O'Donnell H]]
		+	[[Category: Rodriguiz RM]]
		+	[[Category: Roth BL]]
		+	[[Category: Roy K]]
		+	[[Category: Rudnick G]]
		+	[[Category: Sandtner W]]
		+	[[Category: Seth A]]
		+	[[Category: Shoichet BK]]
		+	[[Category: Singh I]]
		+	[[Category: Wetsel WC]]

OCA at 09:46, 23 March 2022

OCA — Wed, 23 Mar 2022 09:46:09 GMT

←Older revision		Revision as of 09:46, 23 March 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7txt is ON HOLD	+	The entry 7txt is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7txt" [edit=sysop:move=sysop]

OCA — Wed, 16 Feb 2022 09:13:44 GMT

Protected "7txt" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:13, 16 February 2022

OCA: New page: '''Unreleased structure''' The entry 7txt is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 16 Feb 2022 09:13:43 GMT

New page: '''Unreleased structure''' The entry 7txt is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7txt is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]