7vcj - Revision history

OCA at 17:23, 29 November 2023

OCA — Wed, 29 Nov 2023 17:23:02 GMT

←Older revision		Revision as of 17:23, 29 November 2023
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	<StructureSection load='7vcj' size='340' side='right'caption='[[7vcj]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='7vcj' size='340' side='right'caption='[[7vcj]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7vcj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VCJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7vcj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Daphnia_magna Daphnia magna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VCJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https:~~/~~/en.wikipedia.org/wiki/Arginine_kinase Arginine kinase]~~, ~~with EC number [https~~:~~//www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.3 2.7.3.3]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vcj OCA], [https://pdbe.org/7vcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vcj RCSB], [https://www.ebi.ac.uk/pdbsum/7vcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vcj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vcj OCA], [https://pdbe.org/7vcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vcj RCSB], [https://www.ebi.ac.uk/pdbsum/7vcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vcj ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0A7CK57_9CRUS A0A0A7CK57_9CRUS]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 7vcj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7vcj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Arginine kinase 3D structures\|Arginine kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arginine kinase~~]]	+	[[Category: Daphnia magna]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jang, K]]	+	[[Category: Jang K]]
-	[[Category: Kim~~, D S~~]]	+	[[Category: Kim DS]]
-	[[Category: Kim~~, W S~~]]	+	[[Category: Kim WS]]
-	[[Category: Kim~~, Y J~~]]	+	[[Category: Kim YJ]]
-	[[Category: Park~~, J H]]~~	+	[[Category: Park JH]]
-	~~[[Category: Secondary structure]]~~	+
-	~~[[Category: Stability]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:33, 2 March 2022

OCA — Wed, 02 Mar 2022 07:33:12 GMT

←Older revision		Revision as of 07:33, 2 March 2022
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	==Arginine kinase H227A from Daphnia magna==		==Arginine kinase H227A from Daphnia magna==
-	<StructureSection load='7vcj' size='340' side='right'caption='[[7vcj]]' scene=''>	+	<StructureSection load='7vcj' size='340' side='right'caption='[[7vcj]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VCJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7vcj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VCJ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vcj OCA], [https://pdbe.org/7vcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vcj RCSB], [https://www.ebi.ac.uk/pdbsum/7vcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vcj ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Arginine_kinase Arginine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.3 2.7.3.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vcj OCA], [https://pdbe.org/7vcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vcj RCSB], [https://www.ebi.ac.uk/pdbsum/7vcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vcj ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Arginine kinase (AK) plays a crucial role in the survival of Daphnia magna, a water flea and a common planktonic invertebrate sensitive to water pollution, owing to the production of bioenergy. AK from D. magna (DmAK) has four highly conserved histidine residues, namely, H90, H227, H284, and H315 in the amino acid sequence. In contrast to DmAK WT (wild type), the enzyme activity of the H227A mutant decreases by 18%. To identify the structure-function relationship of this H227A mutant enzyme, the crystal 3D X-ray structure has been determined and an unfolding assay using anilino-1-naphthalenesulfonic acid (ANS) fluorescence has been undertaken. The results revealed that when compared to the DmAK WT, the hydrogen bonding between H227 and A135 was broken in the H227A crystal structure. This suggests that H227 residue, closed to the arginine binding site, plays an important role in maintaining the structural stability and maximizing the enzyme activity through hydrogen bonding with the backbone oxygen of A135.
		+
		+	Crystal Structure of H227A Mutant of Arginine Kinase in Daphnia magna Suggests the Importance of Its Stability.,Kim DS, Jang K, Kim WS, Ryu M, Park JH, Kim YJ Molecules. 2022 Jan 28;27(3). pii: molecules27030884. doi:, 10.3390/molecules27030884. PMID:35164149<ref>PMID:35164149</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7vcj" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arginine kinase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jang K]]	+	[[Category: Jang, K]]
-	[[Category: Kim DS]]	+	[[Category: Kim, D S]]
-	[[Category: Kim WS]]	+	[[Category: Kim, W S]]
-	[[Category: Kim YJ]]	+	[[Category: Kim, Y J]]
-	[[Category: Park JH]]	+	[[Category: Park, J H]]
		+	[[Category: Secondary structure]]
		+	[[Category: Stability]]
		+	[[Category: Transferase]]

OCA at 10:19, 16 February 2022

OCA — Wed, 16 Feb 2022 10:19:29 GMT

←Older revision		Revision as of 10:19, 16 February 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7vcj ~~is ON HOLD until Paper Publication~~	+	==Arginine kinase H227A from Daphnia magna==
-		+	<StructureSection load='7vcj' size='340' side='right'caption='[[7vcj]]' scene=''>
-	~~Authors~~: ~~Kim, D~~.S., ~~Jang~~, K., ~~Kim, W~~.S., ~~Kim, Y~~.J., ~~Park, J~~.H.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VCJ FirstGlance]. <br>
-	~~Description: Arginine kinase H227A from Daphnia magna~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vcj OCA], [https://pdbe.org/7vcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vcj RCSB], [https://www.ebi.ac.uk/pdbsum/7vcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vcj ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Kim, Y.J~~]]	+	__TOC__
-	[[Category: ~~Jang, K~~]]	+	</StructureSection>
-	[[Category: ~~Park, J.H~~]]	+	[[Category: Large Structures]]
-	[[Category: Kim~~, W.S~~]]	+	[[Category: Jang K]]
-	[[Category: ~~Kim, D.S~~]]	+	[[Category: Kim DS]]
		+	[[Category: Kim WS]]
		+	[[Category: Kim YJ]]
		+	[[Category: Park JH]]

OCA at 05:38, 27 January 2022

OCA — Thu, 27 Jan 2022 05:38:15 GMT

←Older revision		Revision as of 05:38, 27 January 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7vcj is ON HOLD	+	The entry 7vcj is ON HOLD until Paper Publication

	Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.		Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.

OCA at 12:18, 29 December 2021

OCA — Wed, 29 Dec 2021 12:18:42 GMT

←Older revision		Revision as of 12:18, 29 December 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7vcj is ON HOLD ~~until Paper Publication~~	+	The entry 7vcj is ON HOLD

	Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.		Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.

OCA at 05:17, 1 December 2021

OCA — Wed, 01 Dec 2021 05:17:11 GMT

←Older revision		Revision as of 05:17, 1 December 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7vcj is ON HOLD	+	The entry 7vcj is ON HOLD until Paper Publication

	Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.		Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.

OCA: Protected "7vcj" [edit=sysop:move=sysop]

OCA — Wed, 08 Sep 2021 08:05:01 GMT

Protected "7vcj" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:05, 8 September 2021

OCA: New page: '''Unreleased structure''' The entry 7vcj is ON HOLD Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H. Description: Arginine kinase H227A from Daphnia magna [[Category: Un...

OCA — Wed, 08 Sep 2021 08:04:59 GMT

New page: '''Unreleased structure''' The entry 7vcj is ON HOLD Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H. Description: Arginine kinase H227A from Daphnia magna [[Category: Un...

New page

'''Unreleased structure'''

The entry 7vcj is ON HOLD

Authors: Kim, D.S., Jang, K., Kim, W.S., Kim, Y.J., Park, J.H.

Description: Arginine kinase H227A from Daphnia magna
[[Category: Unreleased Structures]]
[[Category: Kim, Y.J]]
[[Category: Jang, K]]
[[Category: Park, J.H]]
[[Category: Kim, W.S]]
[[Category: Kim, D.S]]