7ve0 - Revision history

OCA at 17:23, 29 November 2023

OCA — Wed, 29 Nov 2023 17:23:22 GMT

←Older revision		Revision as of 17:23, 29 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7ve0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VE0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7ve0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VE0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ve0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ve0 OCA], [https://pdbe.org/7ve0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ve0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ve0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ve0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ve0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ve0 OCA], [https://pdbe.org/7ve0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ve0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ve0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ve0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/PLM2_PLAF7 PLM2_PLAF7] During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation (PubMed:29943906). May cleave preferentially denatured hemoglobin that has been cleaved by PMI (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:P46925]<ref>PMID:29943906</ref>		[https://www.uniprot.org/uniprot/PLM2_PLAF7 PLM2_PLAF7] During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation (PubMed:29943906). May cleave preferentially denatured hemoglobin that has been cleaved by PMI (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:P46925]<ref>PMID:29943906</ref>
		+
		+	==See Also==
		+	*[[Plasmepsin\|Plasmepsin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:16, 1 February 2023

OCA — Wed, 01 Feb 2023 11:16:31 GMT

←Older revision		Revision as of 11:16, 1 February 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7ve0 is ~~ON HOLD until 2024~~-03-07	+	==Crystal Structure of Ritonavir bound Plasmepsin II (PMII) from Plasmodium falciparum==
-		+	<StructureSection load='7ve0' size='340' side='right'caption='[[7ve0]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7ve0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VE0 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ve0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ve0 OCA], [https://pdbe.org/7ve0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ve0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ve0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ve0 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PLM2_PLAF7 PLM2_PLAF7] During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation (PubMed:29943906). May cleave preferentially denatured hemoglobin that has been cleaved by PMI (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:P46925]<ref>PMID:29943906</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Plasmodium falciparum 3D7]]
		+	[[Category: Bhaumik P]]
		+	[[Category: Mishra V]]
		+	[[Category: Rathore I]]

OCA at 15:17, 7 September 2022

OCA — Wed, 07 Sep 2022 15:17:47 GMT

←Older revision		Revision as of 15:17, 7 September 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ve0 is ON HOLD until ~~Paper Publication~~	+	The entry 7ve0 is ON HOLD until 2024-03-07

	Authors:		Authors:

OCA at 10:30, 13 October 2021

OCA — Wed, 13 Oct 2021 10:30:58 GMT

←Older revision		Revision as of 10:30, 13 October 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ve0 is ON HOLD	+	The entry 7ve0 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7ve0" [edit=sysop:move=sysop]

OCA — Wed, 15 Sep 2021 08:28:04 GMT

Protected "7ve0" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:28, 15 September 2021

OCA: New page: '''Unreleased structure''' The entry 7ve0 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 15 Sep 2021 08:28:03 GMT

New page: '''Unreleased structure''' The entry 7ve0 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7ve0 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]