OCA at 20:06, 16 November 2022

OCA — Wed, 16 Nov 2022 20:06:54 GMT

←Older revision		Revision as of 20:06, 16 November 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7w0v is ~~ON HOLD until Paper~~ Publication	+	==C4'-SCF3-DT modifeid DNA-DNA duplex==
		+	<StructureSection load='7w0v' size='340' side='right'caption='[[7w0v]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[7w0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Octodon_degus Octodon degus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W0V FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=84E:[(2S,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-2-(trifluoromethylsulfanyl)oxolan-2-yl]methyl+dihydrogen+phosphate'>84E</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w0v OCA], [https://pdbe.org/7w0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w0v RCSB], [https://www.ebi.ac.uk/pdbsum/7w0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w0v ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fluorinated nucleotides are invaluable for (19) F NMR studies of nucleic acid structure and function. Here, we synthesized 4'-SCF3 -thymidine (T 4 ' - SCF 3 ${{^{4{^\prime}\hbox{-}{\rm SCF}{_{3}}}}}$ ) and incorporated it into DNA by means of solid-phase DNA synthesis. NMR studies showed that the 4'-SCF3 group exhibited a flexible orientation in the minor groove of DNA duplexes and was well accommodated by various higher order DNA structures. The three magnetically equivalent fluorine atoms in 4'-SCF3 -DNA constitute an isolated spin system, offering high (19) F NMR sensitivity and excellent resolution of the positioning of T 4 ' - SCF 3 ${{^{4{^\prime}\hbox{-}{\rm SCF}{_{3}}}}}$ within various secondary and tertiary DNA structures. The high structural adaptability and high sensitivity of T 4 ' - SCF 3 ${{^{4{^\prime}\hbox{-}{\rm SCF}{_{3}}}}}$ make it a valuable (19) F NMR probe for quantitatively distinguishing diverse DNA structures with single-nucleotide resolution and for monitoring the dynamics of interactions in the minor groove of double-stranded DNA.

-	~~Authors~~:	+	4'-SCF3 -Labeling Constitutes a Sensitive (19) F NMR Probe for Characterization of Interactions in the Minor Groove of DNA.,Li Q, Trajkovski M, Fan C, Chen J, Zhou Y, Lu K, Li H, Su X, Xi Z, Plavec J, Zhou C Angew Chem Int Ed Engl. 2022 Nov 21;61(47):e202201848. doi:, 10.1002/anie.202201848. Epub 2022 Oct 19. PMID:36163470<ref>PMID:36163470</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 7w0v" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Octodon degus]]
		+	[[Category: Chen J]]
		+	[[Category: Fan C]]
		+	[[Category: Li H]]
		+	[[Category: Li Q]]
		+	[[Category: Lu K]]
		+	[[Category: Plavec J]]
		+	[[Category: Su X]]
		+	[[Category: Trajkovski M]]
		+	[[Category: Xi Z]]
		+	[[Category: Zhou C]]
		+	[[Category: Zhou Y]]

OCA at 05:18, 1 December 2021

OCA — Wed, 01 Dec 2021 05:18:24 GMT

←Older revision		Revision as of 05:18, 1 December 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7w0v is ON HOLD	+	The entry 7w0v is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7w0v" [edit=sysop:move=sysop]

OCA — Wed, 24 Nov 2021 11:12:13 GMT

Protected "7w0v" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:12, 24 November 2021

OCA: New page: '''Unreleased structure''' The entry 7w0v is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 24 Nov 2021 11:12:12 GMT

New page: '''Unreleased structure''' The entry 7w0v is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7w0v is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7w0v - Revision history

OCA at 20:06, 16 November 2022

OCA at 05:18, 1 December 2021

OCA: Protected "7w0v" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7w0v is ON HOLD Authors: Description: Category: Unreleased Structures