7w7r - Revision history

OCA at 17:37, 29 November 2023

OCA — Wed, 29 Nov 2023 17:37:30 GMT

←Older revision		Revision as of 17:37, 29 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7w7r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anabas_testudineus Anabas testudineus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W7R FirstGlance]. <br>		<table><tr><td colspan='2'>[[7w7r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anabas_testudineus Anabas testudineus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W7R FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w7r OCA], [https://pdbe.org/7w7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w7r RCSB], [https://www.ebi.ac.uk/pdbsum/7w7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w7r ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.46Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w7r OCA], [https://pdbe.org/7w7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w7r RCSB], [https://www.ebi.ac.uk/pdbsum/7w7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w7r ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:11, 26 April 2023

OCA — Wed, 26 Apr 2023 17:11:44 GMT

←Older revision		Revision as of 17:11, 26 April 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7w7r is ~~ON HOLD until Paper~~ Publication	+	==High resolution structure of a fish aquaporin reveals a novel extracellular fold.==
		+	<StructureSection load='7w7r' size='340' side='right'caption='[[7w7r]], [[Resolution\|resolution]] 3.46Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[7w7r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anabas_testudineus Anabas testudineus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W7R FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w7r OCA], [https://pdbe.org/7w7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w7r RCSB], [https://www.ebi.ac.uk/pdbsum/7w7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w7r ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/M1K561_ANATE M1K561_ANATE]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aquaporins are protein channels embedded in the lipid bilayer in cells from all organisms on earth that are crucial for water homeostasis. In fish, aquaporins are believed to be important for osmoregulation; however, the molecular mechanism behind this is poorly understood. Here, we present the first structural and functional characterization of a fish aquaporin; cpAQP1aa from the fresh water fish climbing perch (<i>Anabas testudineus</i>), a species that is of high osmoregulatory interest because of its ability to spend time in seawater and on land. These studies show that cpAQP1aa is a water-specific aquaporin with a unique fold on the extracellular side that results in a constriction region. Functional analysis combined with molecular dynamic simulations suggests that phosphorylation at two sites causes structural perturbations in this region that may have implications for channel gating from the extracellular side.

-	~~Authors~~:	+	High-resolution structure of a fish aquaporin reveals a novel extracellular fold.,Zeng J, Schmitz F, Isaksson S, Glas J, Arbab O, Andersson M, Sundell K, Eriksson LA, Swaminathan K, Tornroth-Horsefield S, Hedfalk K Life Sci Alliance. 2022 Oct 13;5(12):e202201491. doi: 10.26508/lsa.202201491. PMID:36229063<ref>PMID:36229063</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 7w7r" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Anabas testudineus]]
		+	[[Category: Large Structures]]
		+	[[Category: Andersson M]]
		+	[[Category: Arbab O]]
		+	[[Category: Eriksson L]]
		+	[[Category: Glas J]]
		+	[[Category: Hedfalk K]]
		+	[[Category: Isaksson S]]
		+	[[Category: Schmitz F]]
		+	[[Category: Sundell K]]
		+	[[Category: Swaminathan K]]
		+	[[Category: Tornroth-Horsefield S]]
		+	[[Category: Zeng J]]

OCA at 06:07, 19 January 2022

OCA — Wed, 19 Jan 2022 06:07:22 GMT

←Older revision		Revision as of 06:07, 19 January 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7w7r is ON HOLD	+	The entry 7w7r is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7w7r" [edit=sysop:move=sysop]

OCA — Wed, 15 Dec 2021 15:49:11 GMT

Protected "7w7r" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:49, 15 December 2021

OCA: New page: '''Unreleased structure''' The entry 7w7r is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 15 Dec 2021 15:49:10 GMT

New page: '''Unreleased structure''' The entry 7w7r is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7w7r is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]