7wi6 - Revision history

OCA at 05:33, 8 September 2022

OCA — Thu, 08 Sep 2022 05:33:51 GMT

←Older revision		Revision as of 05:33, 8 September 2022
Line 3:		Line 3:
	<StructureSection load='7wi6' size='340' side='right'caption='[[7wi6]], [[Resolution\|resolution]] 3.71Å' scene=''>		<StructureSection load='7wi6' size='340' side='right'caption='[[7wi6]], [[Resolution\|resolution]] 3.71Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7wi6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WI6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7wi6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WI6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Z99:2-[(1S,2S)-2-CARBOXYCYCLOPROPYL]-3-(9H-XANTHEN-9-YL)-D-ALANINE'>Z99</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Z99:2-[(1S,2S)-2-CARBOXYCYCLOPROPYL]-3-(9H-XANTHEN-9-YL)-D-ALANINE'>Z99</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wi6 OCA], [https://pdbe.org/7wi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7wi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wi6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wi6 OCA], [https://pdbe.org/7wi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7wi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wi6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GRM3_HUMAN GRM3_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<ref>PMID:8840013</ref>	+	[[https://www.uniprot.org/uniprot/GRM3_HUMAN GRM3_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<ref>PMID:8840013</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fang, W]]	+	[[Category: Fang W]]
-	[[Category: Lin, L]]	+	[[Category: Lin L]]
-	[[Category: Ling~~, S L~~]]	+	[[Category: Ling SL]]
-	[[Category: Liu~~, J F~~]]	+	[[Category: Liu JF]]
-	[[Category: Liu, P]]	+	[[Category: Liu P]]
-	[[Category: Pan, S]]	+	[[Category: Pan S]]
-	[[Category: Pin~~, J P~~]]	+	[[Category: Pin JP]]
-	[[Category: Rondard, P]]	+	[[Category: Rondard P]]
-	[[Category: Sun~~, W J~~]]	+	[[Category: Sun WJ]]
-	[[Category: Tian~~, C L~~]]	+	[[Category: Tian CL]]
-	[[Category: Wang~~, X M~~]]	+	[[Category: Wang XM]]
-	[[Category: Xu~~, C J~~]]	+	[[Category: Xu CJ]]
-	[[Category: Yang, F]]	+	[[Category: Yang F]]
-	[[Category: Zhou~~, Y X]]~~	+	[[Category: Zhou YX]]
-	~~[[Category: Cryo-em]]~~	+
-	~~[[Category: G protein-coupled receptor]]~~	+
-	~~[[Category: Glutamate]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Selective ligand~~]]	+

OCA at 07:18, 20 July 2022

OCA — Wed, 20 Jul 2022 07:18:46 GMT

←Older revision		Revision as of 07:18, 20 July 2022
Line 1:		Line 1:

	==Cryo-EM structure of LY341495/NAM-bound mGlu3==		==Cryo-EM structure of LY341495/NAM-bound mGlu3==
-	<StructureSection load='7wi6' size='340' side='right'caption='[[7wi6]]' scene=''>	+	<StructureSection load='7wi6' size='340' side='right'caption='[[7wi6]], [[Resolution\|resolution]] 3.71Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WI6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7wi6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WI6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wi6 OCA], [https://pdbe.org/7wi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7wi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wi6 ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Z99:2-[(1S,2S)-2-CARBOXYCYCLOPROPYL]-3-(9H-XANTHEN-9-YL)-D-ALANINE'>Z99</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wi6 OCA], [https://pdbe.org/7wi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7wi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wi6 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/GRM3_HUMAN GRM3_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<ref>PMID:8840013</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fang W]]	+	[[Category: Fang, W]]
-	[[Category: Lin L]]	+	[[Category: Lin, L]]
-	[[Category: Ling SL]]	+	[[Category: Ling, S L]]
-	[[Category: Liu JF]]	+	[[Category: Liu, J F]]
-	[[Category: Liu P]]	+	[[Category: Liu, P]]
-	[[Category: Pan S]]	+	[[Category: Pan, S]]
-	[[Category: Pin JP]]	+	[[Category: Pin, J P]]
-	[[Category: Rondard P]]	+	[[Category: Rondard, P]]
-	[[Category: Sun WJ]]	+	[[Category: Sun, W J]]
-	[[Category: Tian CL]]	+	[[Category: Tian, C L]]
-	[[Category: Wang XM]]	+	[[Category: Wang, X M]]
-	[[Category: Xu CJ]]	+	[[Category: Xu, C J]]
-	[[Category: Yang F]]	+	[[Category: Yang, F]]
-	[[Category: Zhou YX]]	+	[[Category: Zhou, Y X]]
		+	[[Category: Cryo-em]]
		+	[[Category: G protein-coupled receptor]]
		+	[[Category: Glutamate]]
		+	[[Category: Membrane protein]]
		+	[[Category: Selective ligand]]

OCA at 06:18, 16 March 2022

OCA — Wed, 16 Mar 2022 06:18:41 GMT

←Older revision		Revision as of 06:18, 16 March 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7wi6 ~~is ON HOLD until Paper Publication~~	+	==Cryo-EM structure of LY341495/NAM-bound mGlu3==
-		+	<StructureSection load='7wi6' size='340' side='right'caption='[[7wi6]]' scene=''>
-	~~Authors~~: ~~Fang, W~~.~~, Yang, F~~.~~, Xu, C~~.J.~~, Ling, S~~.L.~~, Lin, L~~.~~, Zhou, Y~~.X., ~~Sun, W~~.J.~~, Wang, X~~.~~M., Liu~~, P., ~~Rondard, P~~.~~, Pan, S~~.~~, Pin, J.P~~., ~~Tian, C~~.L., ~~Liu, J~~.F.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WI6 FirstGlance]. <br>
-	~~Description: Cryo-EM structure of LY341495~~/~~NAM-bound mGlu3~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wi6 OCA], [https://pdbe.org/7wi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7wi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wi6 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Lin, L~~]]	+	__TOC__
-	[[Category: ~~Xu, C.J~~]]	+	</StructureSection>
-	[[Category: ~~Rondard, P~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Tian, C.L~~]]	+	[[Category: Fang W]]
-	[[Category: ~~Pan, S~~]]	+	[[Category: Lin L]]
-	[[Category: ~~Liu, P~~]]	+	[[Category: Ling SL]]
-	[[Category: ~~Wang, X.M~~]]	+	[[Category: Liu JF]]
-	[[Category: ~~Pin, J.~~P]]	+	[[Category: Liu P]]
-	[[Category: ~~Ling, S.L~~]]	+	[[Category: Pan S]]
-	[[Category: ~~Fang, W~~]]	+	[[Category: Pin JP]]
-	[[Category: ~~Zhou, Y.X~~]]	+	[[Category: Rondard P]]
-	[[Category: ~~Liu, J.F~~]]	+	[[Category: Sun WJ]]
-	[[Category: Yang, F]]	+	[[Category: Tian CL]]
-	[[Category: ~~Sun, W.J~~]]	+	[[Category: Wang XM]]
		+	[[Category: Xu CJ]]
		+	[[Category: Yang F]]
		+	[[Category: Zhou YX]]

OCA at 09:16, 16 February 2022

OCA — Wed, 16 Feb 2022 09:16:09 GMT

←Older revision		Revision as of 09:16, 16 February 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7wi6 is ON HOLD	+	The entry 7wi6 is ON HOLD until Paper Publication

	Authors: Fang, W., Yang, F., Xu, C.J., Ling, S.L., Lin, L., Zhou, Y.X., Sun, W.J., Wang, X.M., Liu, P., Rondard, P., Pan, S., Pin, J.P., Tian, C.L., Liu, J.F.		Authors: Fang, W., Yang, F., Xu, C.J., Ling, S.L., Lin, L., Zhou, Y.X., Sun, W.J., Wang, X.M., Liu, P., Rondard, P., Pan, S., Pin, J.P., Tian, C.L., Liu, J.F.
Line 7:		Line 7:
	Description: Cryo-EM structure of LY341495/NAM-bound mGlu3		Description: Cryo-EM structure of LY341495/NAM-bound mGlu3
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Wang, X.M]]
-	[[Category: Pin, J.P]]
	[[Category: Lin, L]]		[[Category: Lin, L]]
-	[[Category: Ling, S.L]]
	[[Category: Xu, C.J]]		[[Category: Xu, C.J]]
	[[Category: Rondard, P]]		[[Category: Rondard, P]]
-	[[Category: Fang, W]]
	[[Category: Tian, C.L]]		[[Category: Tian, C.L]]
		+	[[Category: Pan, S]]
		+	[[Category: Liu, P]]
		+	[[Category: Wang, X.M]]
		+	[[Category: Pin, J.P]]
		+	[[Category: Ling, S.L]]
		+	[[Category: Fang, W]]
	[[Category: Zhou, Y.X]]		[[Category: Zhou, Y.X]]
	[[Category: Liu, J.F]]		[[Category: Liu, J.F]]
-	[[Category: Pan, S]]
	[[Category: Yang, F]]		[[Category: Yang, F]]
	[[Category: Sun, W.J]]		[[Category: Sun, W.J]]
-	[[Category: Liu, P]]

OCA: Protected "7wi6" [edit=sysop:move=sysop]

OCA — Wed, 12 Jan 2022 08:45:23 GMT

Protected "7wi6" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:45, 12 January 2022

OCA: New page: '''Unreleased structure''' The entry 7wi6 is ON HOLD Authors: Fang, W., Yang, F., Xu, C.J., Ling, S.L., Lin, L., Zhou, Y.X., Sun, W.J., Wang, X.M., Liu, P., Rondard, P., Pan, S., Pin, J...

OCA — Wed, 12 Jan 2022 08:45:22 GMT

New page: '''Unreleased structure''' The entry 7wi6 is ON HOLD Authors: Fang, W., Yang, F., Xu, C.J., Ling, S.L., Lin, L., Zhou, Y.X., Sun, W.J., Wang, X.M., Liu, P., Rondard, P., Pan, S., Pin, J...

New page

'''Unreleased structure'''

The entry 7wi6 is ON HOLD

Authors: Fang, W., Yang, F., Xu, C.J., Ling, S.L., Lin, L., Zhou, Y.X., Sun, W.J., Wang, X.M., Liu, P., Rondard, P., Pan, S., Pin, J.P., Tian, C.L., Liu, J.F.

Description: Cryo-EM structure of LY341495/NAM-bound mGlu3
[[Category: Unreleased Structures]]
[[Category: Wang, X.M]]
[[Category: Pin, J.P]]
[[Category: Lin, L]]
[[Category: Ling, S.L]]
[[Category: Xu, C.J]]
[[Category: Rondard, P]]
[[Category: Fang, W]]
[[Category: Tian, C.L]]
[[Category: Zhou, Y.X]]
[[Category: Liu, J.F]]
[[Category: Pan, S]]
[[Category: Yang, F]]
[[Category: Sun, W.J]]
[[Category: Liu, P]]