7wws - Revision history

OCA at 17:45, 29 November 2023

OCA — Wed, 29 Nov 2023 17:45:11 GMT

←Older revision		Revision as of 17:45, 29 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7wws]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WWS FirstGlance]. <br>		<table><tr><td colspan='2'>[[7wws]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WWS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wws OCA], [https://pdbe.org/7wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wws RCSB], [https://www.ebi.ac.uk/pdbsum/7wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wws ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wws OCA], [https://pdbe.org/7wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wws RCSB], [https://www.ebi.ac.uk/pdbsum/7wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wws ProSAT]</span></td></tr>
	</table>		</table>

OCA at 09:44, 21 June 2023

OCA — Wed, 21 Jun 2023 09:44:57 GMT

←Older revision		Revision as of 09:44, 21 June 2023
Line 1:		Line 1:

	==Structure of a triple-helix region of human collagen type III==		==Structure of a triple-helix region of human collagen type III==
-	<StructureSection load='7wws' size='340' side='right'caption='[[7wws]]' scene=''>	+	<StructureSection load='7wws' size='340' side='right'caption='[[7wws]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WWS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7wws]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WWS FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wws OCA], [https://pdbe.org/7wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wws RCSB], [https://www.ebi.ac.uk/pdbsum/7wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wws ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wws OCA], [https://pdbe.org/7wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wws RCSB], [https://www.ebi.ac.uk/pdbsum/7wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wws ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/CO3A1_HUMAN CO3A1_HUMAN] Defects in COL3A1 are a cause of Ehlers-Danlos syndrome type 3 (EDS3) [MIM:[https://omim.org/entry/130020 130020]; also known as benign hypermobility syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS3 is a form of Ehlers-Danlos syndrome characterized by marked joint hyperextensibility without skeletal deformity.<ref>PMID:7833919</ref> Defects in COL3A1 are the cause of Ehlers-Danlos syndrome type 4 (EDS4) [MIM:[https://omim.org/entry/130050 130050]. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS4 is the most severe form of the disease. It is characterized by the joint and dermal manifestations as in other forms of the syndrome, characteristic facial features (acrogeria) in most patients, and by proneness to spontaneous rupture of bowel and large arteries. The vascular complications may affect all anatomical areas.<ref>PMID:1370809</ref> <ref>PMID:8411057</ref> <ref>PMID:2492273</ref> <ref>PMID:7749417</ref> <ref>PMID:1352273</ref> <ref>PMID:2808425</ref> <ref>PMID:1895316</ref> <ref>PMID:1357232</ref> <ref>PMID:1496983</ref> <ref>PMID:8098182</ref> [:]<ref>PMID:7912131</ref> <ref>PMID:8019562</ref> [:]<ref>PMID:8680408</ref> <ref>PMID:8884076</ref> <ref>PMID:9147870</ref> <ref>PMID:8664902</ref> <ref>PMID:8990011</ref> <ref>PMID:9036918</ref> <ref>PMID:9452103</ref> <ref>PMID:10923041</ref> <ref>PMID:10706896</ref> <ref>PMID:11168790</ref> <ref>PMID:12694234</ref> <ref>PMID:12786757</ref> Defects in COL3A1 are a cause of susceptibility to aortic aneurysm abdominal (AAA) [MIM:[https://omim.org/entry/100070 100070]. AAA is a common multifactorial disorder characterized by permanent dilation of the abdominal aorta, usually due to degenerative changes in the aortic wall. Histologically, AAA is characterized by signs of chronic inflammation, destructive remodeling of the extracellular matrix, and depletion of vascular smooth muscle cells.<ref>PMID:8514866</ref> <ref>PMID:2243125</ref> <ref>PMID:2349939</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CO3A1_HUMAN CO3A1_HUMAN] Collagen type III occurs in most soft connective tissues along with type I collagen.
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Chu Y]]		[[Category: Chu Y]]

OCA at 10:28, 6 April 2022

OCA — Wed, 06 Apr 2022 10:28:20 GMT

←Older revision		Revision as of 10:28, 6 April 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7wws ~~is ON HOLD~~	+	==Structure of a triple-helix region of human collagen type III==
-		+	<StructureSection load='7wws' size='340' side='right'caption='[[7wws]]' scene=''>
-	~~Authors~~: ~~Qian, S~~.~~, Li, H~~., ~~Fan, X~~., ~~Tian, X~~., ~~Li, J~~., ~~Wang, L~~., ~~Chu, Y~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WWS FirstGlance]. <br>
-	~~Description: Structure of a triple-helix region of human collagen type III~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wws OCA], [https://pdbe.org/7wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wws RCSB], [https://www.ebi.ac.uk/pdbsum/7wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wws ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Li, H~~]]	+	__TOC__
-	[[Category: ~~Wang, L~~]]	+	</StructureSection>
-	[[Category: ~~Qian, S~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Chu, Y~~]]	+	[[Category: Chu Y]]
-	[[Category: ~~Li, J~~]]	+	[[Category: Fan X]]
-	[[Category: Tian, X]]	+	[[Category: Li H]]
-	[[Category: ~~Fan, X~~]]	+	[[Category: Li J]]
		+	[[Category: Qian S]]
		+	[[Category: Tian X]]
		+	[[Category: Wang L]]

OCA at 09:58, 23 March 2022

OCA — Wed, 23 Mar 2022 09:58:08 GMT

←Older revision		Revision as of 09:58, 23 March 2022
Line 3:		Line 3:
	The entry 7wws is ON HOLD		The entry 7wws is ON HOLD

-	Authors: Li, H., Li, J., ~~Chu~~, Y., ~~Wang~~, L., ~~Tian~~, X., ~~Fan~~, X., ~~Qian~~, S.	+	Authors: Qian, S., Li, H., Fan, X., Tian, X., Li, J., Wang, L., Chu, Y.

	Description: Structure of a triple-helix region of human collagen type III		Description: Structure of a triple-helix region of human collagen type III
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Li, H]]		[[Category: Li, H]]
		+	[[Category: Wang, L]]
		+	[[Category: Qian, S]]
	[[Category: Chu, Y]]		[[Category: Chu, Y]]
	[[Category: Li, J]]		[[Category: Li, J]]
	[[Category: Tian, X]]		[[Category: Tian, X]]
-	[[Category: Qian, S]]
-	[[Category: Wang, L]]
	[[Category: Fan, X]]		[[Category: Fan, X]]

OCA: Protected "7wws" [edit=sysop:move=sysop]

OCA — Wed, 23 Feb 2022 06:40:20 GMT

Protected "7wws" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:40, 23 February 2022

OCA: New page: '''Unreleased structure''' The entry 7wws is ON HOLD Authors: Li, H., Li, J., Chu, Y., Wang, L., Tian, X., Fan, X., Qian, S. Description: Structure of a triple-helix region of human co...

OCA — Wed, 23 Feb 2022 06:40:19 GMT

New page: '''Unreleased structure''' The entry 7wws is ON HOLD Authors: Li, H., Li, J., Chu, Y., Wang, L., Tian, X., Fan, X., Qian, S. Description: Structure of a triple-helix region of human co...

New page

'''Unreleased structure'''

The entry 7wws is ON HOLD

Authors: Li, H., Li, J., Chu, Y., Wang, L., Tian, X., Fan, X., Qian, S.

Description: Structure of a triple-helix region of human collagen type III
[[Category: Unreleased Structures]]
[[Category: Li, H]]
[[Category: Chu, Y]]
[[Category: Li, J]]
[[Category: Tian, X]]
[[Category: Qian, S]]
[[Category: Wang, L]]
[[Category: Fan, X]]