OCA at 05:58, 2 March 2023

OCA — Thu, 02 Mar 2023 05:58:37 GMT

←Older revision		Revision as of 05:58, 2 March 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7wzw ~~is ON HOLD~~	+	==MEC1-DDC2-MMS==
-		+	<StructureSection load='7wzw' size='340' side='right'caption='[[7wzw]], [[Resolution\|resolution]] 3.80Å' scene=''>
-	~~Authors~~: ~~Zhang~~, Q., ~~Zhang~~, Q.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7wzw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WZW FirstGlance]. <br>
-	~~Description~~: MEC1-~~DDC2~~-~~MMS~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wzw OCA], [https://pdbe.org/7wzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wzw RCSB], [https://www.ebi.ac.uk/pdbsum/7wzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wzw ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Zhang, Q]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/LCD1_YEAST LCD1_YEAST] Forms a complex with the serine/threonine kinase MEC1 which activates checkpoint signaling upon genotoxic stresses. The MEC1-LCD1 complex is recruited by the single-strand-binding protein complex RPA to DNA lesions in order to initiate the DNA repair by homologous recombination, after the MRX-complex and TEL1 are displaced. Required for the recruitment of MEC1 to DNA lesions, the activation of CHK1 and RAD53 kinases and phosphorylation of RAD9 in response to DNA damage. Required for cell growth and meiotic recombination.<ref>PMID:10950868</ref> <ref>PMID:11060031</ref> <ref>PMID:11154263</ref> <ref>PMID:11707419</ref> <ref>PMID:11983176</ref> <ref>PMID:12181334</ref> <ref>PMID:15369670</ref> <ref>PMID:16148046</ref> <ref>PMID:16365046</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Saccharomyces cerevisiae S288C]]
		+	[[Category: Zhang Q]]

OCA at 09:10, 22 February 2023

OCA — Wed, 22 Feb 2023 09:10:26 GMT

←Older revision		Revision as of 09:10, 22 February 2023
Line 3:		Line 3:
	The entry 7wzw is ON HOLD		The entry 7wzw is ON HOLD

-	Authors: Zhang, Q.	+	Authors: Zhang, Q., Zhang, Q.

	Description: MEC1-DDC2-MMS		Description: MEC1-DDC2-MMS
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Zhang, Q]]		[[Category: Zhang, Q]]

OCA: Protected "7wzw" [edit=sysop:move=sysop]

OCA — Wed, 02 Mar 2022 05:14:23 GMT

Protected "7wzw" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:14, 2 March 2022

OCA: New page: '''Unreleased structure''' The entry 7wzw is ON HOLD Authors: Zhang, Q. Description: MEC1-DDC2-MMS Category: Unreleased Structures Category: Zhang, Q

OCA — Wed, 02 Mar 2022 05:14:22 GMT

New page: '''Unreleased structure''' The entry 7wzw is ON HOLD Authors: Zhang, Q. Description: MEC1-DDC2-MMS Category: Unreleased Structures Category: Zhang, Q

New page

'''Unreleased structure'''

The entry 7wzw is ON HOLD

Authors: Zhang, Q.

Description: MEC1-DDC2-MMS
[[Category: Unreleased Structures]]
[[Category: Zhang, Q]]

7wzw - Revision history

OCA at 05:58, 2 March 2023

OCA at 09:10, 22 February 2023

OCA: Protected "7wzw" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7wzw is ON HOLD Authors: Zhang, Q. Description: MEC1-DDC2-MMS Category: Unreleased Structures Category: Zhang, Q