7x5a - Revision history

OCA at 18:11, 20 September 2023

OCA — Wed, 20 Sep 2023 18:11:07 GMT

←Older revision		Revision as of 18:11, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7x5a]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X5A FirstGlance]. <br>		<table><tr><td colspan='2'>[[7x5a]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X5A FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x5a OCA], [https://pdbe.org/7x5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x5a RCSB], [https://www.ebi.ac.uk/pdbsum/7x5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x5a ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.01Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x5a OCA], [https://pdbe.org/7x5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x5a RCSB], [https://www.ebi.ac.uk/pdbsum/7x5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x5a ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/RUVA_PSEAE RUVA_PSEAE] The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA (By similarity). Complements an E.coli deletion mutant (PubMed:8982068).[HAMAP-Rule:MF_00031]<ref>PMID:8982068</ref>		[https://www.uniprot.org/uniprot/RUVA_PSEAE RUVA_PSEAE] The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA (By similarity). Complements an E.coli deletion mutant (PubMed:8982068).[HAMAP-Rule:MF_00031]<ref>PMID:8982068</ref>
		+
		+	==See Also==
		+	*[[Helicase 3D structures\|Helicase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:28, 8 March 2023

OCA — Wed, 08 Mar 2023 07:28:13 GMT

←Older revision		Revision as of 07:28, 8 March 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7x5a ~~is ON HOLD until Paper Publication~~	+	==CryoEM structure of RuvA-Holliday junction complex==
-		+	<StructureSection load='7x5a' size='340' side='right'caption='[[7x5a]], [[Resolution\|resolution]] 3.01Å' scene=''>
-	~~Authors~~: ~~Lin~~, Z., Qu, Q., ~~Zhang, X~~., ~~Zhou, Z~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7x5a]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X5A FirstGlance]. <br>
-	~~Description~~: ~~CryoEM structure of~~ RuvA-Holliday junction complex	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x5a OCA], [https://pdbe.org/7x5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x5a RCSB], [https://www.ebi.ac.uk/pdbsum/7x5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x5a ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Zhou, Z~~]]	+	== Function ==
-	[[Category: Lin, Z]]	+	[https://www.uniprot.org/uniprot/RUVA_PSEAE RUVA_PSEAE] The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA (By similarity). Complements an E.coli deletion mutant (PubMed:8982068).[HAMAP-Rule:MF_00031]<ref>PMID:8982068</ref>
-	[[Category: Zhang, X]]	+	== References ==
-	[[Category: ~~Qu, Q~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Pseudomonas aeruginosa PAO1]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Lin Z]]
		+	[[Category: Qu Q]]
		+	[[Category: Zhang X]]
		+	[[Category: Zhou Z]]

OCA at 09:58, 23 March 2022

OCA — Wed, 23 Mar 2022 09:58:56 GMT

←Older revision		Revision as of 09:58, 23 March 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7x5a is ON HOLD	+	The entry 7x5a is ON HOLD until Paper Publication

	Authors: Lin, Z., Qu, Q., Zhang, X., Zhou, Z.		Authors: Lin, Z., Qu, Q., Zhang, X., Zhou, Z.
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	Description: CryoEM structure of RuvA-Holliday junction complex		Description: CryoEM structure of RuvA-Holliday junction complex
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Zhou, Z]]
	[[Category: Lin, Z]]		[[Category: Lin, Z]]
	[[Category: Zhang, X]]		[[Category: Zhang, X]]
	[[Category: Qu, Q]]		[[Category: Qu, Q]]
-	[[Category: Zhou, Z]]

OCA: Protected "7x5a" [edit=sysop:move=sysop]

OCA — Wed, 09 Mar 2022 05:08:26 GMT

Protected "7x5a" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:08, 9 March 2022

OCA: New page: '''Unreleased structure''' The entry 7x5a is ON HOLD Authors: Lin, Z., Qu, Q., Zhang, X., Zhou, Z. Description: CryoEM structure of RuvA-Holliday junction complex [[Category: Unrelease...

OCA — Wed, 09 Mar 2022 05:08:25 GMT

New page: '''Unreleased structure''' The entry 7x5a is ON HOLD Authors: Lin, Z., Qu, Q., Zhang, X., Zhou, Z. Description: CryoEM structure of RuvA-Holliday junction complex [[Category: Unrelease...

New page

'''Unreleased structure'''

The entry 7x5a is ON HOLD

Authors: Lin, Z., Qu, Q., Zhang, X., Zhou, Z.

Description: CryoEM structure of RuvA-Holliday junction complex
[[Category: Unreleased Structures]]
[[Category: Lin, Z]]
[[Category: Zhang, X]]
[[Category: Qu, Q]]
[[Category: Zhou, Z]]