7x98 - Revision history

OCA at 17:49, 29 November 2023

OCA — Wed, 29 Nov 2023 17:49:37 GMT

←Older revision		Revision as of 17:49, 29 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7x98]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X98 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7x98]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X98 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.05Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x98 OCA], [https://pdbe.org/7x98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x98 RCSB], [https://www.ebi.ac.uk/pdbsum/7x98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x98 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x98 OCA], [https://pdbe.org/7x98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x98 RCSB], [https://www.ebi.ac.uk/pdbsum/7x98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x98 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:28, 8 March 2023

OCA — Wed, 08 Mar 2023 07:28:27 GMT

←Older revision		Revision as of 07:28, 8 March 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7x98 is ~~ON HOLD until Paper~~ Publication	+	==5-Aminolevulinate synthase HemA from Rhodopseudomonas palustris==
		+	<StructureSection load='7x98' size='340' side='right'caption='[[7x98]], [[Resolution\|resolution]] 2.05Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[7x98]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X98 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x98 OCA], [https://pdbe.org/7x98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x98 RCSB], [https://www.ebi.ac.uk/pdbsum/7x98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x98 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/M1FRN3_RHOPL M1FRN3_RHOPL]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	5-ALA is the precursor of all tetrapyrroles. 5-Aminolevulinate synthase (ALAS) catalyzes the production of 5-aminolevulinic acid (5-ALA) from glycine and succinyl-CoA. HemA from Rhodopseudomonas palustris (Rp-HemA) was reported to be a highly active ALAS. To understand the catalytic mechanism of Rp-HemA, the 2.05 A resolution crystal structure of Rp-HemA was solved. Open, half close and close conformations were observed in the substrate-free structures. Structure comparison and sequence alignment suggest the newly observed half close conformation may also be conserved in ALAS family. The pre-existed close and half close conformations in Rp-HemA may play a key role for its high activity.

-	~~Authors~~:	+	Crystal structure of 5-Aminolevulinate synthase HemA from Rhodopseudomonas palustris presents multiple conformations.,Zhang T, Chen J, Zheng P, Gong W, Sun J, Liu H Biochem Biophys Res Commun. 2022 Jun 18;609:100-104. doi: , 10.1016/j.bbrc.2022.04.021. Epub 2022 Apr 9. PMID:35427926<ref>PMID:35427926</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 7x98" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Rhodopseudomonas palustris]]
		+	[[Category: Liu HP]]
		+	[[Category: Zhang TT]]

OCA at 01:41, 21 April 2022

OCA — Thu, 21 Apr 2022 01:41:00 GMT

←Older revision		Revision as of 01:41, 21 April 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7x98 is ON HOLD	+	The entry 7x98 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7x98" [edit=sysop:move=sysop]

OCA — Wed, 23 Mar 2022 10:01:52 GMT

Protected "7x98" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:01, 23 March 2022

OCA: New page: '''Unreleased structure''' The entry 7x98 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 23 Mar 2022 10:01:50 GMT

New page: '''Unreleased structure''' The entry 7x98 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7x98 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]