7xja - Revision history

OCA at 11:19, 15 November 2023

OCA — Wed, 15 Nov 2023 11:19:56 GMT

←Older revision		Revision as of 11:19, 15 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7xja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XJA FirstGlance]. <br>		<table><tr><td colspan='2'>[[7xja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XJA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xja OCA], [https://pdbe.org/7xja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xja RCSB], [https://www.ebi.ac.uk/pdbsum/7xja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xja ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.5Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xja OCA], [https://pdbe.org/7xja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xja RCSB], [https://www.ebi.ac.uk/pdbsum/7xja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xja ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==

OCA at 06:56, 18 May 2023

OCA — Thu, 18 May 2023 06:56:09 GMT

←Older revision		Revision as of 06:56, 18 May 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7xja is ~~ON HOLD~~ ~~until Paper Publication~~	+	==TMD masked refine map of human ClC-2==
-		+	<StructureSection load='7xja' size='340' side='right'caption='[[7xja]], [[Resolution\|resolution]] 3.50Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7xja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XJA FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xja OCA], [https://pdbe.org/7xja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xja RCSB], [https://www.ebi.ac.uk/pdbsum/7xja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xja ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/CLCN2_HUMAN CLCN2_HUMAN] Leukoencephalopathy with mild cerebellar ataxia and white matter edema;Familial hyperaldosteronism type II;Juvenile myoclonic epilepsy. Disease susceptibility is associated with variants affecting the gene represented in this entry. Disease susceptibility may be associated with variants affecting the gene represented in this entry. Disease susceptibility is associated with variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CLCN2_HUMAN CLCN2_HUMAN] Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (PubMed:29403011, PubMed:29403012).<ref>PMID:19153159</ref> <ref>PMID:19191339</ref> <ref>PMID:29403011</ref> <ref>PMID:29403012</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Wang L]]

OCA at 03:56, 8 June 2022

OCA — Wed, 08 Jun 2022 03:56:33 GMT

←Older revision		Revision as of 03:56, 8 June 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7xja is ON HOLD	+	The entry 7xja is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7xja" [edit=sysop:move=sysop]

OCA — Thu, 21 Apr 2022 01:45:08 GMT

Protected "7xja" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:45, 21 April 2022

OCA: New page: '''Unreleased structure''' The entry 7xja is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 21 Apr 2022 01:45:07 GMT

New page: '''Unreleased structure''' The entry 7xja is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7xja is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]