OCA at 07:09, 12 July 2023

OCA — Wed, 12 Jul 2023 07:09:22 GMT

←Older revision		Revision as of 07:09, 12 July 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7xyy is ~~ON HOLD until Paper Publication~~	+	==TRIM E3 ubiquitin ligase WT==
-		+	<StructureSection load='7xyy' size='340' side='right'caption='[[7xyy]], [[Resolution\|resolution]] 7.10Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7xyy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XYY FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 7.1Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xyy OCA], [https://pdbe.org/7xyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xyy RCSB], [https://www.ebi.ac.uk/pdbsum/7xyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xyy ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TRI72_MOUSE TRI72_MOUSE] Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.<ref>PMID:19029292</ref> <ref>PMID:19043407</ref> <ref>PMID:19202355</ref> <ref>PMID:19380584</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Mus musculus]]
		+	[[Category: Park SH]]
		+	[[Category: Song HK]]

OCA at 03:57, 13 July 2022

OCA — Wed, 13 Jul 2022 03:57:33 GMT

←Older revision		Revision as of 03:57, 13 July 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7xyy is ON HOLD	+	The entry 7xyy is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7xyy" [edit=sysop:move=sysop]

OCA — Wed, 08 Jun 2022 04:06:16 GMT

Protected "7xyy" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:06, 8 June 2022

OCA: New page: '''Unreleased structure''' The entry 7xyy is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 08 Jun 2022 04:06:15 GMT

New page: '''Unreleased structure''' The entry 7xyy is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7xyy is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7xyy - Revision history

OCA at 07:09, 12 July 2023

OCA at 03:57, 13 July 2022

OCA: Protected "7xyy" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7xyy is ON HOLD Authors: Description: Category: Unreleased Structures