7y0q - Revision history

OCA at 18:04, 29 November 2023

OCA — Wed, 29 Nov 2023 18:04:48 GMT

←Older revision		Revision as of 18:04, 29 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7y0q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium_NBRC_15308_=_ATCC_14581 Priestia megaterium NBRC 15308 = ATCC 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y0Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[7y0q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium_NBRC_15308_=_ATCC_14581 Priestia megaterium NBRC 15308 = ATCC 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y0Q FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MN:4-METHYLANILINE'>4MN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.31Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MN:4-METHYLANILINE'>4MN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y0q OCA], [https://pdbe.org/7y0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y0q RCSB], [https://www.ebi.ac.uk/pdbsum/7y0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y0q ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y0q OCA], [https://pdbe.org/7y0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y0q RCSB], [https://www.ebi.ac.uk/pdbsum/7y0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y0q ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:11, 14 June 2023

OCA — Wed, 14 Jun 2023 08:11:19 GMT

←Older revision		Revision as of 08:11, 14 June 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7y0q is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with p-toluidine==
-		+	<StructureSection load='7y0q' size='340' side='right'caption='[[7y0q]], [[Resolution\|resolution]] 2.31Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7y0q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium_NBRC_15308_=_ATCC_14581 Priestia megaterium NBRC 15308 = ATCC 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y0Q FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MN:4-METHYLANILINE'>4MN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y0q OCA], [https://pdbe.org/7y0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y0q RCSB], [https://www.ebi.ac.uk/pdbsum/7y0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y0q ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CPXB_PRIM2 CPXB_PRIM2] Functions as a fatty acid monooxygenase (PubMed:3106359, PubMed:1727637, PubMed:16566047, PubMed:7578081, PubMed:11695892, PubMed:14653735, PubMed:16403573, PubMed:18004886, PubMed:17077084, PubMed:17868686, PubMed:18298086, PubMed:18619466, PubMed:18721129, PubMed:19492389, PubMed:20180779, PubMed:21110374, PubMed:21875028). Catalyzes hydroxylation of fatty acids at omega-1, omega-2 and omega-3 positions (PubMed:1727637, PubMed:21875028). Shows activity toward medium and long-chain fatty acids, with optimum chain lengths of 12, 14 and 16 carbons (lauric, myristic, and palmitic acids). Able to metabolize some of these primary metabolites to secondary and tertiary products (PubMed:1727637). Marginal activity towards short chain lengths of 8-10 carbons (PubMed:1727637, PubMed:18619466). Hydroxylates highly branched fatty acids, which play an essential role in membrane fluidity regulation (PubMed:16566047). Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain (PubMed:3106359, PubMed:1727637, PubMed:16566047, PubMed:7578081, PubMed:11695892, PubMed:14653735, PubMed:16403573, PubMed:18004886, PubMed:17077084, PubMed:17868686, PubMed:18298086, PubMed:18619466, PubMed:18721129, PubMed:19492389, PubMed:20180779, PubMed:21110374, PubMed:21875028). Involved in inactivation of quorum sensing signals of other competing bacteria by oxidazing efficiently acyl homoserine lactones (AHLs), molecules involved in quorum sensing signaling pathways, and their lactonolysis products acyl homoserines (AHs) (PubMed:18020460).<ref>PMID:11695892</ref> <ref>PMID:14653735</ref> <ref>PMID:16403573</ref> <ref>PMID:16566047</ref> <ref>PMID:17077084</ref> <ref>PMID:1727637</ref> <ref>PMID:17868686</ref> <ref>PMID:18004886</ref> <ref>PMID:18020460</ref> <ref>PMID:18298086</ref> <ref>PMID:18619466</ref> <ref>PMID:18721129</ref> <ref>PMID:19492389</ref> <ref>PMID:20180779</ref> <ref>PMID:21110374</ref> <ref>PMID:21875028</ref> <ref>PMID:3106359</ref> <ref>PMID:7578081</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Priestia megaterium NBRC 15308 = ATCC 14581]]
		+	[[Category: Cong Z]]
		+	[[Category: Dong S]]
		+	[[Category: Feng Y]]
		+	[[Category: Jiang Y]]

OCA at 03:41, 10 August 2022

OCA — Wed, 10 Aug 2022 03:41:53 GMT

←Older revision		Revision as of 03:41, 10 August 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7y0q is ON HOLD	+	The entry 7y0q is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7y0q" [edit=sysop:move=sysop]

OCA — Wed, 15 Jun 2022 03:57:20 GMT

Protected "7y0q" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:57, 15 June 2022

OCA: New page: '''Unreleased structure''' The entry 7y0q is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 15 Jun 2022 03:57:19 GMT

New page: '''Unreleased structure''' The entry 7y0q is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7y0q is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]