7y35 - Revision history

OCA at 05:37, 5 July 2023

OCA — Wed, 05 Jul 2023 05:37:12 GMT

←Older revision		Revision as of 05:37, 5 July 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7y35 ~~is ON HOLD until Paper Publication~~	+	==Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex==
-		+	<StructureSection load='7y35' size='340' side='right'caption='[[7y35]], [[Resolution\|resolution]] 2.90Å' scene=''>
-	~~Authors~~: ~~Zhai, X~~.~~, Mao, C~~., ~~Shen, Q~~., ~~Zang~~, S., ~~Shen, D~~., ~~Zhang, H~~., ~~Chen, Z~~., ~~Wang, G~~., ~~Zhang, C~~., ~~Zhang, Y~~., ~~Liu, Z~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7y35]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y35 FirstGlance]. <br>
-	~~Description~~: ~~Cryo~~-~~EM structure~~ of ~~the Abaloparatide~~-~~bound human PTH1R-Gs complex~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	[[Category: ~~Zhang, Y~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y35 OCA], [https://pdbe.org/7y35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y35 RCSB], [https://www.ebi.ac.uk/pdbsum/7y35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y35 ProSAT]</span></td></tr>
-	[[Category: ~~Zhang, H~~]]	+	</table>
-	[[Category: Liu, Z]]	+	== Disease ==
-	[[Category: ~~Zhai, X~~]]	+	[https://www.uniprot.org/uniprot/PTH1R_HUMAN PTH1R_HUMAN] Blomstrand lethal chondrodysplasia;Dental ankylosis;Eiken syndrome;Metaphyseal chondrodysplasia, Jansen type;Enchondromatosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease may be caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
-	[[Category: ~~Wang, G~~]]	+	== Function ==
-	[[Category: ~~Zang, S~~]]	+	[https://www.uniprot.org/uniprot/PTH1R_HUMAN PTH1R_HUMAN] This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.<ref>PMID:18611381</ref> <ref>PMID:20172855</ref>
-	[[Category: ~~Chen, Z~~]]	+	== References ==
-	[[Category: ~~Shen, D~~]]	+	<references/>
-	[[Category: Zhang, C]]	+	__TOC__
-	[[Category: ~~Shen, Q~~]]	+	</StructureSection>
-	[[Category: ~~Mao, C~~]]	+	[[Category: Bos taurus]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Rattus norvegicus]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Chen Z]]
		+	[[Category: Liu Z]]
		+	[[Category: Mao C]]
		+	[[Category: Shen D]]
		+	[[Category: Shen Q]]
		+	[[Category: Wang G]]
		+	[[Category: Zang S]]
		+	[[Category: Zhai X]]
		+	[[Category: Zhang C]]
		+	[[Category: Zhang H]]
		+	[[Category: Zhang Y]]

OCA at 19:34, 28 June 2023

OCA — Wed, 28 Jun 2023 19:34:24 GMT

←Older revision		Revision as of 19:34, 28 June 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7y35 is ON HOLD	+	The entry 7y35 is ON HOLD until Paper Publication

	Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, C., Zhang, Y., Liu, Z.		Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, C., Zhang, Y., Liu, Z.

OCA at 04:38, 29 March 2023

OCA — Wed, 29 Mar 2023 04:38:59 GMT

←Older revision		Revision as of 04:38, 29 March 2023
Line 3:		Line 3:
	The entry 7y35 is ON HOLD		The entry 7y35 is ON HOLD

-	Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, Y., Liu, Z.	+	Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, C., Zhang, Y., Liu, Z.

	Description: Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex		Description: Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex
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	[[Category: Chen, Z]]		[[Category: Chen, Z]]
	[[Category: Shen, D]]		[[Category: Shen, D]]
		+	[[Category: Zhang, C]]
	[[Category: Shen, Q]]		[[Category: Shen, Q]]
	[[Category: Mao, C]]		[[Category: Mao, C]]

OCA: Protected "7y35" [edit=sysop:move=sysop]

OCA — Wed, 15 Jun 2022 04:00:59 GMT

Protected "7y35" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:00, 15 June 2022

OCA: New page: '''Unreleased structure''' The entry 7y35 is ON HOLD Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, Y., Liu, Z. Description: Cryo-EM st...

OCA — Wed, 15 Jun 2022 04:00:58 GMT

New page: '''Unreleased structure''' The entry 7y35 is ON HOLD Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, Y., Liu, Z. Description: Cryo-EM st...

New page

'''Unreleased structure'''

The entry 7y35 is ON HOLD

Authors: Zhai, X., Mao, C., Shen, Q., Zang, S., Shen, D., Zhang, H., Chen, Z., Wang, G., Zhang, Y., Liu, Z.

Description: Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex
[[Category: Unreleased Structures]]
[[Category: Zhang, Y]]
[[Category: Zhang, H]]
[[Category: Liu, Z]]
[[Category: Zhai, X]]
[[Category: Wang, G]]
[[Category: Zang, S]]
[[Category: Chen, Z]]
[[Category: Shen, D]]
[[Category: Shen, Q]]
[[Category: Mao, C]]