7y4i - Revision history

OCA at 07:23, 3 April 2024

OCA — Wed, 03 Apr 2024 07:23:52 GMT

←Older revision		Revision as of 07:23, 3 April 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7y4i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y4I FirstGlance]. <br>		<table><tr><td colspan='2'>[[7y4i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y4I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y4i OCA], [https://pdbe.org/7y4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y4i RCSB], [https://www.ebi.ac.uk/pdbsum/7y4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y4i ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y4i OCA], [https://pdbe.org/7y4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y4i RCSB], [https://www.ebi.ac.uk/pdbsum/7y4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y4i ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:15, 7 December 2022

OCA — Wed, 07 Dec 2022 08:15:31 GMT

←Older revision		Revision as of 08:15, 7 December 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7y4i is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of SPINDLY in complex with GDP==
-		+	<StructureSection load='7y4i' size='340' side='right'caption='[[7y4i]], [[Resolution\|resolution]] 2.85Å' scene=''>
-	~~Authors~~: Xu, S.T., ~~Wan~~, L.H.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7y4i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y4I FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure~~ of a ~~novel Glycosyltransferase~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y4i OCA], [https://pdbe.org/7y4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y4i RCSB], [https://www.ebi.ac.uk/pdbsum/7y4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y4i ProSAT]</span></td></tr>
-	[[Category: ~~Xu, S.T~~]]	+	</table>
-	[[Category: Wan~~, L.H~~]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/SPY_ARATH SPY_ARATH] Probable O-linked N-acetylglucosamine transferase (OGT) involved in various processes such as gibberellin (GA) signaling pathway and circadian clock. OGTs catalyze the addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine. Probably acts by adding O-linked sugars to yet unknown proteins. Acts as a repressor of GA signaling pathway to inhibit hypocotyl elongation. Functions with GIGANTEA (GI) in pathways controlling flowering, circadian cotyledon movements and hypocotyl elongation. Acts as a light-regulated promoter of elongation via its interaction with GI. Acts as an activator of cytokinin signaling. Required with SEC for gamete and seed development (PubMed:12136030). Its OGT activity has been proved in vitro but not in vivo (Ref.5, PubMed:11457967, PubMed:12136030, PubMed:15155885, PubMed:15608330, PubMed:8799194). Possesses O-fucosyltransferase activity on specific serine and threonine residues (PubMed:28244988). Mediates O-fucosylation of the DELLA protein RGA, a repressor of the GA signaling pathway (PubMed:28244988). O-fucosylation enhances RGA activity by promoting RGA binding to key transcription factors in brassinosteroid and light-signaling pathways (PubMed:28244988). Regulates root hair patterning upstream of the transcription factor WER, independently of DELLA proteins and GA signaling (PubMed:32928908). Involved in abscisic acid (ABA) signaling partly through functional ABAR (PubMed:34712252). Mediates O-fucosylation of CPN20 that may depress ABA responses during seed germination and seedling development (PubMed:34712252). Involved in the modulation of the pace of the circadian clock by mediating O-fucosylation of APRR5, one of the core circadian clock components (PubMed:31899321). O-fucosylation promotes APRR5 proteolysis (PubMed:31899321).<ref>PMID:11457967</ref> <ref>PMID:12136030</ref> <ref>PMID:15155885</ref> <ref>PMID:15608330</ref> <ref>PMID:28244988</ref> <ref>PMID:31899321</ref> <ref>PMID:32928908</ref> <ref>PMID:34712252</ref> <ref>PMID:8799194</ref> <ref>PMID:12136030</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arabidopsis thaliana]]
		+	[[Category: Large Structures]]
		+	[[Category: Wan LH]]
		+	[[Category: Xu ST]]

OCA at 03:54, 20 July 2022

OCA — Wed, 20 Jul 2022 03:54:35 GMT

←Older revision		Revision as of 03:54, 20 July 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7y4i is ON HOLD	+	The entry 7y4i is ON HOLD until Paper Publication

	Authors: Xu, S.T., Wan, L.H.		Authors: Xu, S.T., Wan, L.H.

-	Description: Crystal Structure ~~Analysis~~ of a ~~N-acetylglucosaminyltransferase~~	+	Description: Crystal Structure of a novel Glycosyltransferase
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Xu, S.T]]		[[Category: Xu, S.T]]
	[[Category: Wan, L.H]]		[[Category: Wan, L.H]]

OCA: Protected "7y4i" [edit=sysop:move=sysop]

OCA — Wed, 22 Jun 2022 07:05:43 GMT

Protected "7y4i" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:05, 22 June 2022

OCA: New page: '''Unreleased structure''' The entry 7y4i is ON HOLD Authors: Xu, S.T., Wan, L.H. Description: Crystal Structure Analysis of a N-acetylglucosaminyltransferase [[Category: Unreleased St...

OCA — Wed, 22 Jun 2022 07:05:42 GMT

New page: '''Unreleased structure''' The entry 7y4i is ON HOLD Authors: Xu, S.T., Wan, L.H. Description: Crystal Structure Analysis of a N-acetylglucosaminyltransferase [[Category: Unreleased St...

New page

'''Unreleased structure'''

The entry 7y4i is ON HOLD

Authors: Xu, S.T., Wan, L.H.

Description: Crystal Structure Analysis of a N-acetylglucosaminyltransferase
[[Category: Unreleased Structures]]
[[Category: Xu, S.T]]
[[Category: Wan, L.H]]