7y7o - Revision history

OCA at 19:46, 29 May 2024

OCA — Wed, 29 May 2024 19:46:49 GMT

←Older revision		Revision as of 19:46, 29 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7y7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y7O FirstGlance]. <br>		<table><tr><td colspan='2'>[[7y7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y7O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y7o OCA], [https://pdbe.org/7y7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y7o RCSB], [https://www.ebi.ac.uk/pdbsum/7y7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y7o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y7o OCA], [https://pdbe.org/7y7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y7o RCSB], [https://www.ebi.ac.uk/pdbsum/7y7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y7o ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:28, 8 March 2023

OCA — Wed, 08 Mar 2023 07:28:41 GMT

←Older revision		Revision as of 07:28, 8 March 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7y7o is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of metallo-endoribonuclease YbeY from Staphylococcus aureus==
		+	<StructureSection load='7y7o' size='340' side='right'caption='[[7y7o]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[7y7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y7O FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y7o OCA], [https://pdbe.org/7y7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y7o RCSB], [https://www.ebi.ac.uk/pdbsum/7y7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y7o ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/YBEY_STAAM YBEY_STAAM] Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Endoribonuclease YbeY is specific to the single-stranded RNA of ribosomal RNAs and small RNAs. This enzyme is essential for the maturation and quality control of ribosomal RNA in a wide range of bacteria and for virulence in some pathogenic bacteria. In this study, we determined the crystal structure of YbeY from Staphylococcus aureus at a resolution of 1.9 A in the presence of zinc chloride. The structure showed a zinc ion at the active site and two molecules of tricarboxylic acid citrate, which were also derived from the crystallization conditions. Our structure showed the zinc ion-bound local environment at the molecular level for the first time. Molecular comparisons were performed between the carboxylic moieties of citrate and the phosphate moiety of the RNA backbone, and a model of YbeY in complex with a single strand of RNA was subsequently constructed. Our findings provide molecular insights into how the YbeY enzyme recognizes single-stranded RNA in bacteria.

-	~~Authors: Lee~~, J., Ha, N.-C.	+	Crystal Structure of the Metallo-Endoribonuclease YbeY from Staphylococcus aureus.,Lee J, Jo I, Kwon AR, Ha NC J Microbiol Biotechnol. 2023 Jan 28;33(1):28-34. doi: 10.4014/jmb.2209.09019. , Epub 2022 Nov 23. PMID:36457189<ref>PMID:36457189</ref>

-	~~Description: Crystal structure~~ of ~~metallo~~-~~endoribonuclease YbeY from Staphylococcus aureus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Ha, N.-C]]	+	<div class="pdbe-citations 7y7o" style="background-color:#fffaf0;"></div>
-	[[Category: Lee, J]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Staphylococcus aureus subsp. aureus Mu50]]
		+	[[Category: Ha N-C]]
		+	[[Category: Lee J]]

OCA at 14:56, 6 July 2022

OCA — Wed, 06 Jul 2022 14:56:01 GMT

←Older revision		Revision as of 14:56, 6 July 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7y7o is ON HOLD	+	The entry 7y7o is ON HOLD until Paper Publication

	Authors: Lee, J., Ha, N.-C.		Authors: Lee, J., Ha, N.-C.

OCA: Protected "7y7o" [edit=sysop:move=sysop]

OCA — Wed, 29 Jun 2022 06:10:59 GMT

Protected "7y7o" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:10, 29 June 2022

OCA: New page: '''Unreleased structure''' The entry 7y7o is ON HOLD Authors: Lee, J., Ha, N.-C. Description: Crystal structure of metallo-endoribonuclease YbeY from Staphylococcus aureus [[Category: ...

OCA — Wed, 29 Jun 2022 06:10:58 GMT

New page: '''Unreleased structure''' The entry 7y7o is ON HOLD Authors: Lee, J., Ha, N.-C. Description: Crystal structure of metallo-endoribonuclease YbeY from Staphylococcus aureus [[Category: ...

New page

'''Unreleased structure'''

The entry 7y7o is ON HOLD

Authors: Lee, J., Ha, N.-C.

Description: Crystal structure of metallo-endoribonuclease YbeY from Staphylococcus aureus
[[Category: Unreleased Structures]]
[[Category: Ha, N.-C]]
[[Category: Lee, J]]