OCA at 07:59, 6 December 2023

OCA — Wed, 06 Dec 2023 07:59:02 GMT

←Older revision		Revision as of 07:59, 6 December 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7yc2 is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of auxiliary protein in complex with human protein==
-		+	<StructureSection load='7yc2' size='340' side='right'caption='[[7yc2]], [[Resolution\|resolution]] 2.90Å' scene=''>
-	~~Authors~~: ~~Gao~~, X., ~~Cui~~, S.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7yc2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YC2 FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of auxiliary protein~~ in complex with ~~human~~ protein	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yc2 OCA], [https://pdbe.org/7yc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yc2 RCSB], [https://www.ebi.ac.uk/pdbsum/7yc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yc2 ProSAT]</span></td></tr>
-	[[Category: ~~Gao, X~~]]	+	</table>
-	[[Category: Cui, S]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/ZY11B_HUMAN ZY11B_HUMAN] Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZER1 to target substrates bearing N-terminal glycine degrons for proteasomal degradation (PubMed:33093214). Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation (PubMed:31273098).<ref>PMID:31273098</ref> <ref>PMID:33093214</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Severe acute respiratory syndrome coronavirus 2]]
		+	[[Category: Cui S]]
		+	[[Category: Gao X]]

OCA at 16:24, 27 July 2022

OCA — Wed, 27 Jul 2022 16:24:17 GMT

←Older revision		Revision as of 16:24, 27 July 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7yc2 is ON HOLD	+	The entry 7yc2 is ON HOLD until Paper Publication

	Authors: Gao, X., Cui, S.		Authors: Gao, X., Cui, S.

OCA: Protected "7yc2" [edit=sysop:move=sysop]

OCA — Wed, 06 Jul 2022 15:00:26 GMT

Protected "7yc2" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:00, 6 July 2022

OCA: New page: '''Unreleased structure''' The entry 7yc2 is ON HOLD Authors: Gao, X., Cui, S. Description: Crystal structure of auxiliary protein in complex with human protein [[Category: Unreleased ...

OCA — Wed, 06 Jul 2022 15:00:25 GMT

New page: '''Unreleased structure''' The entry 7yc2 is ON HOLD Authors: Gao, X., Cui, S. Description: Crystal structure of auxiliary protein in complex with human protein [[Category: Unreleased ...

New page

'''Unreleased structure'''

The entry 7yc2 is ON HOLD

Authors: Gao, X., Cui, S.

Description: Crystal structure of auxiliary protein in complex with human protein
[[Category: Unreleased Structures]]
[[Category: Gao, X]]
[[Category: Cui, S]]

7yc2 - Revision history

OCA at 07:59, 6 December 2023

OCA at 16:24, 27 July 2022

OCA: Protected "7yc2" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7yc2 is ON HOLD Authors: Gao, X., Cui, S. Description: Crystal structure of auxiliary protein in complex with human protein [[Category: Unreleased ...