7ywe - Revision history

OCA at 13:26, 1 February 2024

OCA — Thu, 01 Feb 2024 13:26:47 GMT

←Older revision		Revision as of 13:26, 1 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7ywe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[7ywe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YWE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ywe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ywe OCA], [https://pdbe.org/7ywe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ywe RCSB], [https://www.ebi.ac.uk/pdbsum/7ywe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ywe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ywe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ywe OCA], [https://pdbe.org/7ywe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ywe RCSB], [https://www.ebi.ac.uk/pdbsum/7ywe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ywe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q306J3_ORYSJ Q306J3_ORYSJ]] Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.[RuleBase:RU363099]	+	[https://www.uniprot.org/uniprot/Q306J3_ORYSJ Q306J3_ORYSJ] Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.[RuleBase:RU363099]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:06, 14 September 2022

OCA — Wed, 14 Sep 2022 07:06:16 GMT

←Older revision		Revision as of 07:06, 14 September 2022
Line 1:		Line 1:

	==Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (crystal form 2)==		==Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (crystal form 2)==
-	<StructureSection load='7ywe' size='340' side='right'caption='[[7ywe]]' scene=''>	+	<StructureSection load='7ywe' size='340' side='right'caption='[[7ywe]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YWE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7ywe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YWE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ywe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ywe OCA], [https://pdbe.org/7ywe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ywe RCSB], [https://www.ebi.ac.uk/pdbsum/7ywe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ywe ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ywe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ywe OCA], [https://pdbe.org/7ywe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ywe RCSB], [https://www.ebi.ac.uk/pdbsum/7ywe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ywe ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/Q306J3_ORYSJ Q306J3_ORYSJ]] Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.[RuleBase:RU363099]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pesticides are routinely used to prevent severe losses in agriculture. This practice is under debate because of its potential negative environmental impact and selection of resistances in pathogens. Therefore, the development of disease resistant plants is mandatory. It was shown that the rice (Oryza sativa) protein OsJAC1 enhances resistance against different bacterial and fungal plant pathogens in rice, barley, and wheat. Recently we reported possible carbohydrate interaction partners for both domains of OsJAC1 (a jacalin-related lectin (JRL) and a dirigent (DIR) domain), however, a mechanistic understanding of its function is still lacking. Here, we report crystal structures for both individual domains and the complex of galactobiose with the DIR domain, which revealed a new carbohydrate binding motif for DIR proteins. Docking studies of the two domains led to a model of the full-length protein. Our findings offer insights into structure and binding properties of OsJAC1 and its possible function in pathogen resistance.
		+
		+	The Crystal Structure of the Defense Conferring Rice Protein OsJAC1 Reveals a Carbohydrate Binding Site on the Dirigent-like Domain.,Huwa N, Weiergraber OH, Fejzagic AV, Kirsch C, Schaffrath U, Classen T Biomolecules. 2022 Aug 17;12(8). pii: biom12081126. doi: 10.3390/biom12081126. PMID:36009020<ref>PMID:36009020</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7ywe" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Oryza sativa]]
	[[Category: Classen T]]		[[Category: Classen T]]
	[[Category: Huwa N]]		[[Category: Huwa N]]
	[[Category: Weiergraeber OH]]		[[Category: Weiergraeber OH]]

OCA at 12:55, 4 May 2022

OCA — Wed, 04 May 2022 12:55:04 GMT

←Older revision		Revision as of 12:55, 4 May 2022
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-	'''Unreleased structure'''

-	~~The entry 7ywe is ON HOLD until Apr 13 2023~~	+	==Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (crystal form 2)==
-		+	<StructureSection load='7ywe' size='340' side='right'caption='[[7ywe]]' scene=''>
-	~~Authors: Huwa, N., Classen, T., Weiergraeber, O.H.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YWE FirstGlance]. <br>
-	~~Description:~~ Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (crystal form 2)	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ywe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ywe OCA], [https://pdbe.org/7ywe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ywe RCSB], [https://www.ebi.ac.uk/pdbsum/7ywe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ywe ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Weiergraeber~~, O.H]]	+	__TOC__
-	[[Category: Classen, T]]	+	</StructureSection>
-	[[Category: Huwa, N]]	+	[[Category: Large Structures]]
		+	[[Category: Classen T]]
		+	[[Category: Huwa N]]
		+	[[Category: Weiergraeber OH]]

OCA at 10:04, 23 March 2022

OCA — Wed, 23 Mar 2022 10:04:41 GMT

←Older revision		Revision as of 10:04, 23 March 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ywe is ON HOLD	+	The entry 7ywe is ON HOLD until Apr 13 2023

	Authors: Huwa, N., Classen, T., Weiergraeber, O.H.		Authors: Huwa, N., Classen, T., Weiergraeber, O.H.

OCA: Protected "7ywe" [edit=sysop:move=sysop]

OCA — Wed, 23 Feb 2022 06:45:07 GMT

Protected "7ywe" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:45, 23 February 2022

OCA: New page: '''Unreleased structure''' The entry 7ywe is ON HOLD Authors: Huwa, N., Classen, T., Weiergraeber, O.H. Description: Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (c...

OCA — Wed, 23 Feb 2022 06:45:06 GMT

New page: '''Unreleased structure''' The entry 7ywe is ON HOLD Authors: Huwa, N., Classen, T., Weiergraeber, O.H. Description: Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (c...

New page

'''Unreleased structure'''

The entry 7ywe is ON HOLD

Authors: Huwa, N., Classen, T., Weiergraeber, O.H.

Description: Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (crystal form 2)
[[Category: Unreleased Structures]]
[[Category: Weiergraeber, O.H]]
[[Category: Classen, T]]
[[Category: Huwa, N]]