7yx3 - Revision history

OCA at 07:32, 12 July 2023

OCA — Wed, 12 Jul 2023 07:32:25 GMT

←Older revision		Revision as of 07:32, 12 July 2023
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	==Structure of the Mimivirus genomic fibre in its compact 6-start helix form==		==Structure of the Mimivirus genomic fibre in its compact 6-start helix form==
-	<StructureSection load='7yx3' size='340' side='right'caption='[[7yx3]]' scene=''>	+	<StructureSection load='7yx3' size='340' side='right'caption='[[7yx3]], [[Resolution\|resolution]] 4.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7yx3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_polyphaga_mimivirus Acanthamoeba polyphaga mimivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx3 OCA], [https://pdbe.org/7yx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx3 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx3 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx3 OCA], [https://pdbe.org/7yx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx3 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/YR135_MIMIV YR135_MIMIV]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 microm icosahedral capsids. Cryo-electron microscopy, cryo-electron tomography and proteomics revealed that it is encased into a ~30 nm diameter helical protein shell surprisingly composed of two GMC-type oxidoreductases, which also form the glycosylated fibrils decorating the capsid. The genome is arranged in 5- or 6-start left-handed super-helices, with each DNA-strand lining the central channel. This luminal channel of the nucleoprotein fiber is wide enough to accommodate oxidative stress proteins and RNA polymerase subunits identified by proteomics. Such elegant supramolecular organization would represent a remarkable evolutionary strategy for packaging and protecting the genome, in a state ready for immediate transcription upon unwinding in the host cytoplasm. The parsimonious use of the same protein in two unrelated substructures of the virion is unexpected for a giant virus with thousand genes at its disposal.
		+
		+	The giant mimivirus 1.2 Mb genome is elegantly organized into a 30 nm diameter helical protein shield.,Villalta A, Schmitt A, Estrozi LF, Quemin ERJ, Alempic JM, Lartigue A, Prazak V, Belmudes L, Vasishtan D, Colmant AMG, Honore FA, Coute Y, Grunewald K, Abergel C Elife. 2022 Jul 28;11. pii: 77607. doi: 10.7554/eLife.77607. PMID:35900198<ref>PMID:35900198</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7yx3" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Acanthamoeba polyphaga mimivirus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Abergel C]]		[[Category: Abergel C]]

OCA at 05:02, 10 August 2022

OCA — Wed, 10 Aug 2022 05:02:43 GMT

←Older revision		Revision as of 05:02, 10 August 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7yx3 is ~~ON HOLD until Paper Publication~~	+	==Structure of the Mimivirus genomic fibre in its compact 6-start helix form==
-		+	<StructureSection load='7yx3' size='340' side='right'caption='[[7yx3]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX3 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx3 OCA], [https://pdbe.org/7yx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx3 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx3 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Abergel C]]
		+	[[Category: Alempic JM]]
		+	[[Category: Belmudes L]]
		+	[[Category: Colmant AMG]]
		+	[[Category: Coute Y]]
		+	[[Category: Estrozi LF]]
		+	[[Category: Grunewald K]]
		+	[[Category: Honore FA]]
		+	[[Category: Lartigue A]]
		+	[[Category: Prazak V]]
		+	[[Category: Quemin ERJ]]
		+	[[Category: Schmitt A]]
		+	[[Category: Vasishtan D]]
		+	[[Category: Villalta A]]

OCA at 10:04, 23 March 2022

OCA — Wed, 23 Mar 2022 10:04:58 GMT

←Older revision		Revision as of 10:04, 23 March 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7yx3 is ON HOLD	+	The entry 7yx3 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7yx3" [edit=sysop:move=sysop]

OCA — Wed, 23 Feb 2022 06:46:19 GMT

Protected "7yx3" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:46, 23 February 2022

OCA: New page: '''Unreleased structure''' The entry 7yx3 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 23 Feb 2022 06:46:18 GMT

New page: '''Unreleased structure''' The entry 7yx3 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7yx3 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]