7yx6 - Revision history

OCA at 13:26, 1 February 2024

OCA — Thu, 01 Feb 2024 13:26:59 GMT

←Older revision		Revision as of 13:26, 1 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-1H-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-1H-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref>	+	[https://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:26, 8 September 2022

OCA — Thu, 08 Sep 2022 07:26:15 GMT

←Older revision		Revision as of 07:26, 8 September 2022
Line 3:		Line 3:
	<StructureSection load='7yx6' size='340' side='right'caption='[[7yx6]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='7yx6' size='340' side='right'caption='[[7yx6]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-1H-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-1H-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref>	+	[[https://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Caflisch, A]]	+	[[Category: Caflisch A]]
-	[[Category: Li, Y]]	+	[[Category: Li Y]]
-	[[Category: Nai, F]]	+	[[Category: Nai F]]
-	~~[[Category: Epitranscriptomic reader]]~~	+
-	~~[[Category: M6a reader]]~~	+
-	~~[[Category: Rna binding protein~~]]	+

OCA at 16:27, 6 July 2022

OCA — Wed, 06 Jul 2022 16:27:57 GMT

←Older revision		Revision as of 16:27, 6 July 2022
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-~~5~{H}~~-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-1H-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:27, 16 March 2022

OCA — Wed, 16 Mar 2022 07:27:16 GMT

←Older revision		Revision as of 07:27, 16 March 2022
Line 1:		Line 1:

	==Crystal structure of YTHDF2 with compound YLI_DF_027==		==Crystal structure of YTHDF2 with compound YLI_DF_027==
-	<StructureSection load='7yx6' size='340' side='right'caption='[[7yx6]]' scene=''>	+	<StructureSection load='7yx6' size='340' side='right'caption='[[7yx6]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7yx6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I6R:6-ethyl-5~{H}-pyrimidine-2,4-dione'>I6R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Caflisch A]]	+	[[Category: Caflisch, A]]
-	[[Category: Li Y]]	+	[[Category: Li, Y]]
-	[[Category: Nai F]]	+	[[Category: Nai, F]]
		+	[[Category: Epitranscriptomic reader]]
		+	[[Category: M6a reader]]
		+	[[Category: Rna binding protein]]

OCA: Protected "7yx6" [edit=sysop:move=sysop]

OCA — Wed, 23 Feb 2022 07:45:33 GMT

Protected "7yx6" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:45, 23 February 2022

OCA: New page: ==Crystal structure of YTHDF2 with compound YLI_DF_027== == Structural highlights ==

OCA — Wed, 23 Feb 2022 07:45:31 GMT

New page: ==Crystal structure of YTHDF2 with compound YLI_DF_027== <StructureSection load='7yx6' size='340' side='right'caption='7yx6' scene=''> == Structural highlights == <table><tr><td colsp...

New page

==Crystal structure of YTHDF2 with compound YLI_DF_027==
<StructureSection load='7yx6' size='340' side='right'caption='[[7yx6]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YX6 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yx6 OCA], [https://pdbe.org/7yx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yx6 RCSB], [https://www.ebi.ac.uk/pdbsum/7yx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yx6 ProSAT]</span></td></tr>
</table>
TOC
</StructureSection>
[[Category: Large Structures]]
[[Category: Caflisch A]]
[[Category: Li Y]]
[[Category: Nai F]]