7zyi - Revision history

OCA at 05:35, 8 September 2022

OCA — Thu, 08 Sep 2022 05:35:11 GMT

←Older revision		Revision as of 05:35, 8 September 2022
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-	====	+	==Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody==
-	<StructureSection load='7zyi' size='340' side='right'caption='[[7zyi]]' scene=''>	+	<StructureSection load='7zyi' size='340' side='right'caption='[[7zyi]], [[Resolution\|resolution]] 2.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7zyi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZYI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zyi OCA], [https://pdbe.org/7zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zyi RCSB], [https://www.ebi.ac.uk/pdbsum/7zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zyi ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHO:GLYCOCHENODEOXYCHOLIC+ACID'>CHO</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zyi OCA], [https://pdbe.org/7zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zyi RCSB], [https://www.ebi.ac.uk/pdbsum/7zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zyi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[[https://www.uniprot.org/uniprot/NTCP_HUMAN NTCP_HUMAN]] The disease is caused by variants affecting the gene represented in this entry.
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/NTCP_HUMAN NTCP_HUMAN]] As a major transporter of conjugated bile salts from plasma into the hepatocyte, it has a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. Able to transport taurocholate, cholate, and the non-bile acid estron sulfate (PubMed:14660639, PubMed:24867799).<ref>PMID:14660639</ref> <ref>PMID:24867799</ref> (Microbial infection) Acts as a receptor for hepatitis B virus.<ref>PMID:23150796</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Lama glama]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Z-~~disk~~]]	+	[[Category: Mus musculus]]
		+	[[Category: Agrawal P]]
		+	[[Category: Bang-Sorensen R]]
		+	[[Category: Irobalieva RN]]
		+	[[Category: Kossiakoff AA]]
		+	[[Category: Liu H]]
		+	[[Category: Locher KP]]
		+	[[Category: Mukherjee S]]
		+	[[Category: Nosol K]]
		+	[[Category: Stieger B]]

OCA at 05:19, 13 July 2022

OCA — Wed, 13 Jul 2022 05:19:47 GMT

←Older revision		Revision as of 05:19, 13 July 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7zyi ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7zyi' size='340' side='right'caption='[[7zyi]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zyi OCA], [https://pdbe.org/7zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zyi RCSB], [https://www.ebi.ac.uk/pdbsum/7zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zyi ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 06:17, 29 June 2022

OCA — Wed, 29 Jun 2022 06:17:59 GMT

←Older revision		Revision as of 06:17, 29 June 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7zyi is ON HOLD ~~until sometime in the future~~	+	The entry 7zyi is ON HOLD

	Authors:		Authors:

OCA: Protected "7zyi" [edit=sysop:move=sysop]

OCA — Wed, 08 Jun 2022 04:18:05 GMT

Protected "7zyi" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:18, 8 June 2022

OCA: New page: '''Unreleased structure''' The entry 7zyi is ON HOLD until sometime in the future Authors: Description: Category: Unreleased Structures

OCA — Wed, 08 Jun 2022 04:18:04 GMT

New page: '''Unreleased structure''' The entry 7zyi is ON HOLD until sometime in the future Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7zyi is ON HOLD until sometime in the future

Authors:

Description:
[[Category: Unreleased Structures]]