OCA at 08:19, 16 August 2023

OCA — Wed, 16 Aug 2023 08:19:29 GMT

←Older revision		Revision as of 08:19, 16 August 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8alx is ~~ON HOLD until Paper Publication~~	+	==Structure of human PD-L1 in complex with inhibitor==
-		+	<StructureSection load='8alx' size='340' side='right'caption='[[8alx]], [[Resolution\|resolution]] 1.10Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8alx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALX FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.1Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9KK:N-methyl+norleucine'>9KK</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CCS:CARBOXYMETHYLATED+CYSTEINE'>CCS</scene>, <scene name='pdbligand=DAB:2,4-DIAMINOBUTYRIC+ACID'>DAB</scene>, <scene name='pdbligand=DPP:DIAMINOPROPANOIC+ACID'>DPP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=MAA:N-METHYL-L-ALANINE'>MAA</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=V6W:NE-Acetyl-L-tryptophan'>V6W</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8alx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8alx OCA], [https://pdbe.org/8alx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8alx RCSB], [https://www.ebi.ac.uk/pdbsum/8alx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8alx ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Grudnik P]]
		+	[[Category: Holak T]]
		+	[[Category: Magiera-Mularz K]]
		+	[[Category: Rodriguez I]]

OCA at 04:41, 9 November 2022

OCA — Wed, 09 Nov 2022 04:41:14 GMT

←Older revision		Revision as of 04:41, 9 November 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8alx is ON HOLD	+	The entry 8alx is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8alx" [edit=sysop:move=sysop]

OCA — Wed, 10 Aug 2022 03:56:58 GMT

Protected "8alx" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:56, 10 August 2022

OCA: New page: '''Unreleased structure''' The entry 8alx is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 10 Aug 2022 03:56:57 GMT

New page: '''Unreleased structure''' The entry 8alx is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8alx is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

8alx - Revision history

OCA at 08:19, 16 August 2023

OCA at 04:41, 9 November 2022

OCA: Protected "8alx" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8alx is ON HOLD Authors: Description: Category: Unreleased Structures