8b3i - Revision history

OCA at 06:52, 27 September 2023

OCA — Wed, 27 Sep 2023 06:52:53 GMT

←Older revision		Revision as of 06:52, 27 September 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8b3i is ~~ON HOLD until Paper Publication~~	+	==CRL4CSA-E2-Ub (state 2)==
-		+	<StructureSection load='8b3i' size='340' side='right'caption='[[8b3i]], [[Resolution\|resolution]] 3.50Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8b3i]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B3I FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.5Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b3i OCA], [https://pdbe.org/8b3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b3i RCSB], [https://www.ebi.ac.uk/pdbsum/8b3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b3i ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/UB2D2_HUMAN UB2D2_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.<ref>PMID:10329681</ref> <ref>PMID:15280377</ref> <ref>PMID:18042044</ref> <ref>PMID:18703417</ref> <ref>PMID:18359941</ref> <ref>PMID:19854139</ref> <ref>PMID:20403326</ref> <ref>PMID:20061386</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Cramer P]]
		+	[[Category: Kokic G]]

OCA at 07:56, 21 June 2023

OCA — Wed, 21 Jun 2023 07:56:39 GMT

←Older revision		Revision as of 07:56, 21 June 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8b3i is ON HOLD	+	The entry 8b3i is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 02:17, 25 May 2023

OCA — Thu, 25 May 2023 02:17:58 GMT

←Older revision		Revision as of 02:17, 25 May 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8b3i is ON HOLD ~~until sometime in the future~~	+	The entry 8b3i is ON HOLD

	Authors:		Authors:

OCA at 16:45, 19 October 2022

OCA — Wed, 19 Oct 2022 16:45:30 GMT

←Older revision		Revision as of 16:45, 19 October 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8b3i is ON HOLD	+	The entry 8b3i is ON HOLD until sometime in the future

	Authors:		Authors:

OCA: Protected "8b3i" [edit=sysop:move=sysop]

OCA — Wed, 28 Sep 2022 04:35:27 GMT

Protected "8b3i" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:35, 28 September 2022

OCA: New page: '''Unreleased structure''' The entry 8b3i is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 28 Sep 2022 04:35:26 GMT

New page: '''Unreleased structure''' The entry 8b3i is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8b3i is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]