8bwy - Revision history

OCA at 21:25, 28 June 2023

OCA — Wed, 28 Jun 2023 21:25:53 GMT

←Older revision		Revision as of 21:25, 28 June 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8bwy]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BWY FirstGlance]. <br>		<table><tr><td colspan='2'>[[8bwy]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BWY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 38Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bwy OCA], [https://pdbe.org/8bwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bwy RCSB], [https://www.ebi.ac.uk/pdbsum/8bwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bwy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bwy OCA], [https://pdbe.org/8bwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bwy RCSB], [https://www.ebi.ac.uk/pdbsum/8bwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bwy ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:51, 10 May 2023

OCA — Wed, 10 May 2023 06:51:58 GMT

←Older revision		Revision as of 06:51, 10 May 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8bwy is ~~ON HOLD~~	+	==In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state==
		+	<StructureSection load='8bwy' size='340' side='right'caption='[[8bwy]], [[Resolution\|resolution]] 38.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8bwy]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BWY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bwy OCA], [https://pdbe.org/8bwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bwy RCSB], [https://www.ebi.ac.uk/pdbsum/8bwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bwy ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/I7M9J2_TETTS I7M9J2_TETTS]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Axonemal outer dynein arm (ODA) motors generate force for ciliary beating. We analyzed three states of the ODA during the power stroke cycle using in situ cryo-electron tomography, subtomogram averaging, and classification. These states of force generation depict the prepower stroke, postpower stroke, and intermediate state conformations. Comparison of these conformations to published in vitro atomic structures of cytoplasmic dynein, ODA, and the Shulin-ODA complex revealed differences in the orientation and position of the dynein head. Our analysis shows that in the absence of ATP, all dynein linkers interact with the AAA3/AAA4 domains, indicating that interactions with the adjacent microtubule doublet B-tubule direct dynein orientation. For the prepower stroke conformation, there were changes in the tail that is anchored on the A-tubule. We built models starting with available high-resolution structures to generate a best-fitting model structure for the in situ pre- and postpower stroke ODA conformations, thereby showing that ODA in a complex with Shulin adopts a similar conformation as the active prepower stroke ODA in the axoneme.

-	~~Authors~~:	+	ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.,Zimmermann N, Noga A, Obbineni JM, Ishikawa T EMBO J. 2023 Apr 13:e112466. doi: 10.15252/embj.2022112466. PMID:37051721<ref>PMID:37051721</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 8bwy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chlamydomonas reinhardtii]]
		+	[[Category: Large Structures]]
		+	[[Category: Ishikawa T]]
		+	[[Category: Noga A]]
		+	[[Category: Obbineni JM]]
		+	[[Category: Zimmermann NEL]]

OCA at 04:50, 18 January 2023

OCA — Wed, 18 Jan 2023 04:50:08 GMT

←Older revision		Revision as of 04:50, 18 January 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8bwy is ON HOLD ~~until sometime in the future~~	+	The entry 8bwy is ON HOLD

	Authors:		Authors:

OCA at 05:30, 28 December 2022

OCA — Wed, 28 Dec 2022 05:30:06 GMT

←Older revision		Revision as of 05:30, 28 December 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8bwy is ON HOLD	+	The entry 8bwy is ON HOLD until sometime in the future

	Authors:		Authors:

OCA: Protected "8bwy" [edit=sysop:move=sysop]

OCA — Wed, 14 Dec 2022 07:29:38 GMT

Protected "8bwy" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:29, 14 December 2022

OCA: New page: '''Unreleased structure''' The entry 8bwy is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 14 Dec 2022 07:29:37 GMT

New page: '''Unreleased structure''' The entry 8bwy is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8bwy is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]