OCA at 23:10, 27 December 2023

OCA — Wed, 27 Dec 2023 23:10:02 GMT

←Older revision		Revision as of 23:10, 27 December 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8bzf ~~is ON HOLD~~	+	==FC-J acetonide stabilizer of 14-3-3 and ERalpha==
-		+	<StructureSection load='8bzf' size='340' side='right'caption='[[8bzf]], [[Resolution\|resolution]] 1.53Å' scene=''>
-	~~Authors~~: ~~Visser~~, E.J., ~~Ottmann~~, C.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8bzf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BZF FirstGlance]. <br>
-	~~Description~~: ~~FC-J acetonide stabilizer~~ of ~~14-3-3~~ and ~~ERalpha~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.53Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SJ4:Fusicoccin+J-acetonide'>SJ4</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-	[[Category: Ottmann, C]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bzf OCA], [https://pdbe.org/8bzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bzf RCSB], [https://www.ebi.ac.uk/pdbsum/8bzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bzf ProSAT]</span></td></tr>
-	[[Category: Visser~~, E.J~~]]	+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Ottmann C]]
		+	[[Category: Visser EJ]]

OCA: Protected "8bzf" [edit=sysop:move=sysop]

OCA — Wed, 21 Dec 2022 06:15:01 GMT

Protected "8bzf" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:15, 21 December 2022

OCA: New page: '''Unreleased structure''' The entry 8bzf is ON HOLD Authors: Visser, E.J., Ottmann, C. Description: FC-J acetonide stabilizer of 14-3-3 and ERalpha Category: Unreleased Structures...

OCA — Wed, 21 Dec 2022 06:15:00 GMT

New page: '''Unreleased structure''' The entry 8bzf is ON HOLD Authors: Visser, E.J., Ottmann, C. Description: FC-J acetonide stabilizer of 14-3-3 and ERalpha Category: Unreleased Structures...

New page

'''Unreleased structure'''

The entry 8bzf is ON HOLD

Authors: Visser, E.J., Ottmann, C.

Description: FC-J acetonide stabilizer of 14-3-3 and ERalpha
[[Category: Unreleased Structures]]
[[Category: Ottmann, C]]
[[Category: Visser, E.J]]

8bzf - Revision history

OCA at 23:10, 27 December 2023

OCA: Protected "8bzf" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8bzf is ON HOLD Authors: Visser, E.J., Ottmann, C. Description: FC-J acetonide stabilizer of 14-3-3 and ERalpha Category: Unreleased Structures...