8ce2 - Revision history

OCA at 05:39, 31 May 2023

OCA — Wed, 31 May 2023 05:39:17 GMT

←Older revision		Revision as of 05:39, 31 May 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8ce2 is ~~ON HOLD until Paper~~ Publication	+	==X-ray structure of the adduct formed upon reaction of a B-DNA double helical dodecamer with dirhodium tetraacetate==
		+	<StructureSection load='8ce2' size='340' side='right'caption='[[8ce2]], [[Resolution\|resolution]] 1.24Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8ce2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/DNA_molecule DNA molecule]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CE2 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RH:RHODIUM'>RH</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ce2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ce2 OCA], [https://pdbe.org/8ce2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ce2 RCSB], [https://www.ebi.ac.uk/pdbsum/8ce2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ce2 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The reaction of the cytotoxic compound dirhodium tetraacetate with a B-DNA double helical dodecamer was studied by X-ray crystallography and mass spectrometry. The structure of the dirhodium/DNA adduct reveals a dimetallic center binding to an adenine via axial coordination. Complementary information has been gained through ESI MS measurements. Comparison between the present data and those previously obtained for cisplatin indicates that the two metallodrugs react with this DNA dodecamer in a significantly different fashion.

-	~~Authors: Tito~~, G., Troisi, R., Ferraro, G., ~~Sica~~, F., Merlino, A.	+	Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry.,Tito G, Troisi R, Ferraro G, Geri A, Massai L, Messori L, Sica F, Merlino A Dalton Trans. 2023 May 30;52(21):6992-6996. doi: 10.1039/d3dt00320e. PMID:37199244<ref>PMID:37199244</ref>

-	~~Description: X-ray structure~~ of the ~~adduct formed upon reaction~~ of ~~a B~~-DNA ~~double helical dodecamer with dirhodium tetraacetate~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Ferraro, G]]	+	<div class="pdbe-citations 8ce2" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Tito, G~~]]	+	== References ==
-	[[Category: Sica, F]]	+	<references/>
-	[[Category: ~~Merlino, A~~]]	+	__TOC__
-	[[Category: Troisi, R]]	+	</StructureSection>
		+	[[Category: DNA molecule]]
		+	[[Category: Large Structures]]
		+	[[Category: Ferraro G]]
		+	[[Category: Merlino A]]
		+	[[Category: Sica F]]
		+	[[Category: Tito G]]
		+	[[Category: Troisi R]]

OCA at 14:48, 26 April 2023

OCA — Wed, 26 Apr 2023 14:48:19 GMT

←Older revision		Revision as of 14:48, 26 April 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8ce2 is ON HOLD	+	The entry 8ce2 is ON HOLD until Paper Publication

	Authors: Tito, G., Troisi, R., Ferraro, G., Sica, F., Merlino, A.		Authors: Tito, G., Troisi, R., Ferraro, G., Sica, F., Merlino, A.

OCA at 04:44, 7 April 2023

OCA — Fri, 07 Apr 2023 04:44:56 GMT

←Older revision		Revision as of 04:44, 7 April 2023
Line 3:		Line 3:
	The entry 8ce2 is ON HOLD		The entry 8ce2 is ON HOLD

-	Authors: Tito, G., ~~Merlino~~, A., Ferraro, G., Sica, F., ~~Troisi~~, R.	+	Authors: Tito, G., Troisi, R., Ferraro, G., Sica, F., Merlino, A.

	Description: X-ray structure of the adduct formed upon reaction of a B-DNA double helical dodecamer with dirhodium tetraacetate		Description: X-ray structure of the adduct formed upon reaction of a B-DNA double helical dodecamer with dirhodium tetraacetate
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	[[Category: Ferraro, G]]		[[Category: Ferraro, G]]
	[[Category: Tito, G]]		[[Category: Tito, G]]
-	[[Category: Troisi, R]]
-	[[Category: Merlino, A]]
	[[Category: Sica, F]]		[[Category: Sica, F]]
		+	[[Category: Merlino, A]]
		+	[[Category: Troisi, R]]

OCA: Protected "8ce2" [edit=sysop:move=sysop]

OCA — Wed, 08 Feb 2023 05:03:35 GMT

Protected "8ce2" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:03, 8 February 2023

OCA: New page: '''Unreleased structure''' The entry 8ce2 is ON HOLD Authors: Tito, G., Merlino, A., Ferraro, G., Sica, F., Troisi, R. Description: X-ray structure of the adduct formed upon reaction o...

OCA — Wed, 08 Feb 2023 05:03:34 GMT

New page: '''Unreleased structure''' The entry 8ce2 is ON HOLD Authors: Tito, G., Merlino, A., Ferraro, G., Sica, F., Troisi, R. Description: X-ray structure of the adduct formed upon reaction o...

New page

'''Unreleased structure'''

The entry 8ce2 is ON HOLD

Authors: Tito, G., Merlino, A., Ferraro, G., Sica, F., Troisi, R.

Description: X-ray structure of the adduct formed upon reaction of a B-DNA double helical dodecamer with dirhodium tetraacetate
[[Category: Unreleased Structures]]
[[Category: Ferraro, G]]
[[Category: Tito, G]]
[[Category: Troisi, R]]
[[Category: Merlino, A]]
[[Category: Sica, F]]