8czu - Revision history

OCA at 10:04, 25 October 2023

OCA — Wed, 25 Oct 2023 10:04:49 GMT

←Older revision		Revision as of 10:04, 25 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8czu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>		<table><tr><td colspan='2'>[[8czu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9R:[(1~{S},2~{S})-2-(cyclohexylmethyl)cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P9R</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9R:[(1~{S},2~{S})-2-(cyclohexylmethyl)cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P9R</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:50, 11 January 2023

OCA — Wed, 11 Jan 2023 07:50:27 GMT

←Older revision		Revision as of 07:50, 11 January 2023
Line 8:		Line 8:
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]]	+	[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 04:03, 8 September 2022

OCA — Thu, 08 Sep 2022 04:03:02 GMT

←Older revision		Revision as of 04:03, 8 September 2022
Line 3:		Line 3:
	<StructureSection load='8czu' size='340' side='right'caption='[[8czu]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='8czu' size='340' side='right'caption='[[8czu]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[8czu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[8czu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9R:[(1~{S},2~{S})-2-(cyclohexylmethyl)cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P9R</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9R:[(1~{S},2~{S})-2-(cyclohexylmethyl)cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P9R</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Battaile~~, K P~~]]	+	[[Category: Middle East respiratory syndrome-related coronavirus]]
-	[[Category: Chamandi~~, S D~~]]	+	[[Category: Battaile KP]]
-	[[Category: Chang~~, K O~~]]	+	[[Category: Chamandi SD]]
-	[[Category: Groutas~~, W C~~]]	+	[[Category: Chang KO]]
-	[[Category: Kim, Y]]	+	[[Category: Groutas WC]]
-	[[Category: Liu, L]]	+	[[Category: Kim Y]]
-	[[Category: Lovell, S]]	+	[[Category: Liu L]]
-	[[Category: Madden~~, T K~~]]	+	[[Category: Lovell S]]
-	[[Category: Nguyen~~, H N~~]]	+	[[Category: Madden TK]]
-	[[Category: Picard~~, H R~~]]	+	[[Category: Nguyen HN]]
-	[[Category: Thruman~~, H A]]~~	+	[[Category: Picard HR]]
-	~~[[Category: Hydrolase]]~~	+	[[Category: Thruman HA]]
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Mers 3cl protease inhhibitor]]~~	+
-	~~[[Category: Protease]]~~	+
-	~~[[Category: Severe acute respiratory syndrome coronavirus 2~~]]	+

OCA at 05:05, 3 August 2022

OCA — Wed, 03 Aug 2022 05:05:52 GMT

←Older revision		Revision as of 05:05, 3 August 2022
Line 1:		Line 1:

-	==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor ~~17d~~==	+	==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 16d==
-	<StructureSection load='8czu' size='340' side='right'caption='[[8czu]]' scene=''>	+	<StructureSection load='8czu' size='340' side='right'caption='[[8czu]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[8czu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9R:[(1~{S},2~{S})-2-(cyclohexylmethyl)cyclopropyl]methyl+~{N}-[(2~{S})-1-[[(2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P9R</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Battaile KP]]	+	[[Category: Battaile, K P]]
-	[[Category: Chamandi SD]]	+	[[Category: Chamandi, S D]]
-	[[Category: Chang KO]]	+	[[Category: Chang, K O]]
-	[[Category: Groutas WC]]	+	[[Category: Groutas, W C]]
-	[[Category: Kim Y]]	+	[[Category: Kim, Y]]
-	[[Category: Liu L]]	+	[[Category: Liu, L]]
-	[[Category: Lovell S]]	+	[[Category: Lovell, S]]
-	[[Category: Madden TK]]	+	[[Category: Madden, T K]]
-	[[Category: Nguyen HN]]	+	[[Category: Nguyen, H N]]
-	[[Category: Picard HR]]	+	[[Category: Picard, H R]]
-	[[Category: Thruman HA]]	+	[[Category: Thruman, H A]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Mers 3cl protease inhhibitor]]
		+	[[Category: Protease]]
		+	[[Category: Severe acute respiratory syndrome coronavirus 2]]

OCA at 09:49, 22 June 2022

OCA — Wed, 22 Jun 2022 09:49:03 GMT

←Older revision		Revision as of 09:49, 22 June 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8czu is ~~ON HOLD~~	+	==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 17d==
-		+	<StructureSection load='8czu' size='340' side='right'caption='[[8czu]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZU FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czu OCA], [https://pdbe.org/8czu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czu RCSB], [https://www.ebi.ac.uk/pdbsum/8czu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czu ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Battaile KP]]
		+	[[Category: Chamandi SD]]
		+	[[Category: Chang KO]]
		+	[[Category: Groutas WC]]
		+	[[Category: Kim Y]]
		+	[[Category: Liu L]]
		+	[[Category: Lovell S]]
		+	[[Category: Madden TK]]
		+	[[Category: Nguyen HN]]
		+	[[Category: Picard HR]]
		+	[[Category: Thruman HA]]

OCA at 04:09, 15 June 2022

OCA — Wed, 15 Jun 2022 04:09:19 GMT

←Older revision		Revision as of 04:09, 15 June 2022
Line 3:		Line 3:
	The entry 8czu is ON HOLD		The entry 8czu is ON HOLD

-	Authors: ~~Liu, L., Lovell, S., Battaile, K.P., Nguyen, H.N., Chamandi, S.D., Picard, H.R., Madden, T.K., Thruman, H.A., Kim, Y., Groutas, W.C., Chang, K.O.~~	+	Authors:

-	Description: ~~Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 17d~~	+	Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Groutas, W.C]]
-	[[Category: Battaile, K.P]]
-	[[Category: Liu, L]]
-	[[Category: Chamandi, S.D]]
-	[[Category: Chang, K.O]]
-	[[Category: Thruman, H.A]]
-	[[Category: Picard, H.R]]
-	[[Category: Kim, Y]]
-	[[Category: Lovell, S]]
-	[[Category: Madden, T.K]]
-	[[Category: Nguyen, H.N]]

OCA: Protected "8czu" [edit=sysop:move=sysop]

OCA — Wed, 08 Jun 2022 04:29:51 GMT

Protected "8czu" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:29, 8 June 2022

OCA: New page: '''Unreleased structure''' The entry 8czu is ON HOLD Authors: Liu, L., Lovell, S., Battaile, K.P., Nguyen, H.N., Chamandi, S.D., Picard, H.R., Madden, T.K., Thruman, H.A., Kim, Y., Grou...

OCA — Wed, 08 Jun 2022 04:29:50 GMT

New page: '''Unreleased structure''' The entry 8czu is ON HOLD Authors: Liu, L., Lovell, S., Battaile, K.P., Nguyen, H.N., Chamandi, S.D., Picard, H.R., Madden, T.K., Thruman, H.A., Kim, Y., Grou...

New page

'''Unreleased structure'''

The entry 8czu is ON HOLD

Authors: Liu, L., Lovell, S., Battaile, K.P., Nguyen, H.N., Chamandi, S.D., Picard, H.R., Madden, T.K., Thruman, H.A., Kim, Y., Groutas, W.C., Chang, K.O.

Description: Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 17d
[[Category: Unreleased Structures]]
[[Category: Groutas, W.C]]
[[Category: Battaile, K.P]]
[[Category: Liu, L]]
[[Category: Chamandi, S.D]]
[[Category: Chang, K.O]]
[[Category: Thruman, H.A]]
[[Category: Picard, H.R]]
[[Category: Kim, Y]]
[[Category: Lovell, S]]
[[Category: Madden, T.K]]
[[Category: Nguyen, H.N]]