8d0o - Revision history

OCA at 06:58, 9 August 2023

OCA — Wed, 09 Aug 2023 06:58:14 GMT

←Older revision		Revision as of 06:58, 9 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8d0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D0O FirstGlance]. <br>		<table><tr><td colspan='2'>[[8d0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D0O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d0o OCA], [https://pdbe.org/8d0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d0o RCSB], [https://www.ebi.ac.uk/pdbsum/8d0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d0o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d0o OCA], [https://pdbe.org/8d0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d0o RCSB], [https://www.ebi.ac.uk/pdbsum/8d0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d0o ProSAT]</span></td></tr>
	</table>		</table>

OCA at 04:03, 25 May 2023

OCA — Thu, 25 May 2023 04:03:27 GMT

←Older revision		Revision as of 04:03, 25 May 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8d0o is ~~ON HOLD until Paper Publication~~	+	==Human alpha1,3-fucosyltransferase FUT9, heavy atom derivative==
-		+	<StructureSection load='8d0o' size='340' side='right'caption='[[8d0o]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8d0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D0O FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d0o OCA], [https://pdbe.org/8d0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d0o RCSB], [https://www.ebi.ac.uk/pdbsum/8d0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d0o ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/FUT9_HUMAN FUT9_HUMAN] Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosynthesis in neurons which allows cell differentiation, cell adhesion, and initiation of neurite outgrowth (PubMed:23263199, PubMed:23192350, PubMed:10386598, PubMed:17335083, PubMed:23000574, PubMed:11278338, PubMed:10622713, PubMed:18395013, PubMed:12107078, PubMed:16282604, PubMed:29593094). Also fucosylates di-, tri- and tetraantennary N-glycans linked to glycoproteins and the inner lactosamine unit of the alpha2,3-sialylated polylactosamine resulting in sLex (CD15s) epitope synthesis (PubMed:12107078, PubMed:18395013). Furthermore, it is capable of synthesizing Lewis a (Lea), although to a lesser extent than Lex and Lewis y (Ley) and to confer SELE-dependent, but not SELL- and SELP-selectin-dependent, cell rolling and adhesion by enhancing Lex and sLex synthesis (PubMed:18395013, PubMed:23192350). May also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE.<ref>PMID:10386598</ref> <ref>PMID:10622713</ref> <ref>PMID:11278338</ref> <ref>PMID:12107078</ref> <ref>PMID:16282604</ref> <ref>PMID:17335083</ref> <ref>PMID:18395013</ref> <ref>PMID:23000574</ref> <ref>PMID:23192350</ref> <ref>PMID:23263199</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Kadirvelraj R]]
		+	[[Category: Wood ZA]]

OCA at 04:09, 15 June 2022

OCA — Wed, 15 Jun 2022 04:09:29 GMT

←Older revision		Revision as of 04:09, 15 June 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8d0o is ON HOLD	+	The entry 8d0o is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8d0o" [edit=sysop:move=sysop]

OCA — Wed, 08 Jun 2022 04:31:11 GMT

Protected "8d0o" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:31, 8 June 2022

OCA: New page: '''Unreleased structure''' The entry 8d0o is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 08 Jun 2022 04:31:10 GMT

New page: '''Unreleased structure''' The entry 8d0o is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8d0o is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]