OCA at 10:37, 2 August 2023

OCA — Wed, 02 Aug 2023 10:37:17 GMT

←Older revision		Revision as of 10:37, 2 August 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8dyk is ~~ON HOLD until Paper~~ Publication	+	==Room temperature neutron structure of a fluorescent Ag8 cluster templated by a multistranded DNA scaffold==
		+	<StructureSection load='8dyk' size='340' side='right'caption='[[8dyk]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8dyk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DYK FirstGlance]. <br>
		+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Neutron Diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AG:SILVER+ION'>AG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dyk OCA], [https://pdbe.org/8dyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dyk RCSB], [https://www.ebi.ac.uk/pdbsum/8dyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dyk ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	When strands of DNA encapsulate silver clusters, supramolecular optical chromophores develop. However, how a particular structure endows a specific spectrum remains poorly understood. Here, we used neutron diffraction to map protonation in (A(2)C(4))(2)-Ag(8), a green-emitting fluorophore with a "Big Dipper" arrangement of silvers. The DNA host has two substructures with distinct protonation patterns. Three cytosines from each strand collectively chelate handle-like array of three silvers, and calorimetry studies suggest Ag(+) cross-links. The twisted cytosines are further joined by hydrogen bonds from fully protonated amines. The adenines and their neighboring cytosine from each strand anchor a dipper-like group of five silvers via their deprotonated endo- and exocyclic nitrogens. Typically, exocyclic amines are strongly basic, so their acidification and deprotonation in (A(2)C(4))(2)-Ag(8) suggest that silvers perturb the electron distribution in the aromatic nucleobases. The different protonation states in (A(2)C(4))(2)-Ag(8) suggest that atomic level structures can pinpoint how to control and tune the electronic spectra of these nanoscale chromophores.

-	~~Authors: Meilleur~~, F., Lieberman, ~~R.L.~~, Petty, J.T.	+	Mapping H(+) in the Nanoscale (A(2)C(4))(2)-Ag(8) Fluorophore.,David F, Setzler C, Sorescu A, Lieberman RL, Meilleur F, Petty JT J Phys Chem Lett. 2022 Dec 8;13(48):11317-11322. doi: , 10.1021/acs.jpclett.2c03161. Epub 2022 Dec 1. PMID:36453924<ref>PMID:36453924</ref>

-	~~Description: Room temperature neutron structure of~~ a ~~fluorescent Ag8 cluster templated by a multistranded DNA scaffold~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Meilleur, F~~]]	+	<div class="pdbe-citations 8dyk" style="background-color:#fffaf0;"></div>
-	[[Category: Lieberman~~, R.L~~]]	+	== References ==
-	[[Category: Petty~~, J.T~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Lieberman RL]]
		+	[[Category: Meilleur F]]
		+	[[Category: Petty JT]]

OCA at 04:04, 18 August 2022

OCA — Thu, 18 Aug 2022 04:04:54 GMT

←Older revision		Revision as of 04:04, 18 August 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8dyk is ON HOLD	+	The entry 8dyk is ON HOLD until Paper Publication

	Authors: Meilleur, F., Lieberman, R.L., Petty, J.T.		Authors: Meilleur, F., Lieberman, R.L., Petty, J.T.

OCA: Protected "8dyk" [edit=sysop:move=sysop]

OCA — Wed, 10 Aug 2022 04:07:31 GMT

Protected "8dyk" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:07, 10 August 2022

OCA: New page: '''Unreleased structure''' The entry 8dyk is ON HOLD Authors: Meilleur, F., Lieberman, R.L., Petty, J.T. Description: Room temperature neutron structure of a fluorescent Ag8 cluster te...

OCA — Wed, 10 Aug 2022 04:07:30 GMT

New page: '''Unreleased structure''' The entry 8dyk is ON HOLD Authors: Meilleur, F., Lieberman, R.L., Petty, J.T. Description: Room temperature neutron structure of a fluorescent Ag8 cluster te...

New page

'''Unreleased structure'''

The entry 8dyk is ON HOLD

Authors: Meilleur, F., Lieberman, R.L., Petty, J.T.

Description: Room temperature neutron structure of a fluorescent Ag8 cluster templated by a multistranded DNA scaffold
[[Category: Unreleased Structures]]
[[Category: Meilleur, F]]
[[Category: Lieberman, R.L]]
[[Category: Petty, J.T]]

8dyk - Revision history

OCA at 10:37, 2 August 2023

OCA at 04:04, 18 August 2022

OCA: Protected "8dyk" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8dyk is ON HOLD Authors: Meilleur, F., Lieberman, R.L., Petty, J.T. Description: Room temperature neutron structure of a fluorescent Ag8 cluster te...