OCA at 21:17, 28 June 2023

OCA — Wed, 28 Jun 2023 21:17:11 GMT

←Older revision		Revision as of 21:17, 28 June 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8e3l ~~is ON HOLD until Paper Publication~~	+	==E. coli 50S ribosome bound to D-linker solithromycin conjugate==
-		+	<StructureSection load='8e3l' size='340' side='right'caption='[[8e3l]], [[Resolution\|resolution]] 2.35Å' scene=''>
-	~~Authors~~: ~~Pellegrino~~, J., ~~Lee~~, D.J., ~~Fraser~~, J.S., ~~Seiple~~, I.B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8e3l]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E3L FirstGlance]. <br>
-	~~Description~~: E. ~~coli~~ 50S ~~ribosome bound~~ to D-~~linker solithromycin conjugate~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.35Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MG:1N-METHYLGUANOSINE-5-MONOPHOSPHATE'>1MG</scene>, <scene name='pdbligand=2MA:2-METHYLADENOSINE-5-MONOPHOSPHATE'>2MA</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=3TD:(1S)-1,4-ANHYDRO-1-(3-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-5-O-PHOSPHONO-D-RIBITOL'>3TD</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=6MZ:N6-METHYLADENOSINE-5-MONOPHOSPHATE'>6MZ</scene>, <scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=UK3:(2~{R})-~{N}-[(2~{R})-6-azanyl-1-[[(2~{R})-1-[[(2~{R})-1-[[3-[1-[4-[(1~{S},2~{R},5~{S},7~{R},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-5-fluoranyl-9-methoxy-1,5,7,11,13-pentamethyl-4,6,12,16-tetrakis(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-15-yl]butyl]-1,2,3-triazol-4-yl]phenyl]amino]-4-methylsulfanyl-1-oxidanylidene-butan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]-1-[(2~{R})-2-[[(2~{R})-2-[2-[[2,3-bis(oxidanyl)phenyl]carbonyl-[4-[[2,3-bis(oxidanyl)phenyl]carbonylamino]butyl]amino]ethanoylamino]-3-(1~{H}-indol-3-yl)propanoyl]amino]-3-oxidanyl-propanoyl]pyrrolidine-2-carboxamide'>UK3</scene></td></tr>
-	[[Category: Fraser~~, J.S~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e3l OCA], [https://pdbe.org/8e3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e3l RCSB], [https://www.ebi.ac.uk/pdbsum/8e3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e3l ProSAT]</span></td></tr>
-	[[Category: ~~Pellegrino, J~~]]	+	</table>
-	[[Category: ~~Seiple, I.B~~]]	+	== Function ==
-	[[Category: ~~Lee, D.J~~]]	+	[https://www.uniprot.org/uniprot/S1EW51_ECOLX S1EW51_ECOLX] This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.[HAMAP-Rule:MF_01366][RuleBase:RU003878][SAAS:SAAS00725369]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
		+	[[Category: Fraser JS]]
		+	[[Category: Lee DJ]]
		+	[[Category: Pellegrino J]]
		+	[[Category: Seiple IB]]

OCA at 05:33, 31 August 2022

OCA — Wed, 31 Aug 2022 05:33:45 GMT

←Older revision		Revision as of 05:33, 31 August 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8e3l is ON HOLD	+	The entry 8e3l is ON HOLD until Paper Publication

	Authors: Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.		Authors: Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.

OCA: Protected "8e3l" [edit=sysop:move=sysop]

OCA — Thu, 25 Aug 2022 03:53:07 GMT

Protected "8e3l" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:53, 25 August 2022

OCA: New page: '''Unreleased structure''' The entry 8e3l is ON HOLD Authors: Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B. Description: E. coli 50S ribosome bound to D-linker solithromycin co...

OCA — Thu, 25 Aug 2022 03:53:06 GMT

New page: '''Unreleased structure''' The entry 8e3l is ON HOLD Authors: Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B. Description: E. coli 50S ribosome bound to D-linker solithromycin co...

New page

'''Unreleased structure'''

The entry 8e3l is ON HOLD

Authors: Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B.

Description: E. coli 50S ribosome bound to D-linker solithromycin conjugate
[[Category: Unreleased Structures]]
[[Category: Fraser, J.S]]
[[Category: Pellegrino, J]]
[[Category: Seiple, I.B]]
[[Category: Lee, D.J]]

8e3l - Revision history

OCA at 21:17, 28 June 2023

OCA at 05:33, 31 August 2022

OCA: Protected "8e3l" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8e3l is ON HOLD Authors: Pellegrino, J., Lee, D.J., Fraser, J.S., Seiple, I.B. Description: E. coli 50S ribosome bound to D-linker solithromycin co...