8frd - Revision history

OCA at 06:22, 19 July 2023

OCA — Wed, 19 Jul 2023 06:22:18 GMT

←Older revision		Revision as of 06:22, 19 July 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8frd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FRD FirstGlance]. <br>		<table><tr><td colspan='2'>[[8frd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FRD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.68Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8frd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8frd OCA], [https://pdbe.org/8frd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8frd RCSB], [https://www.ebi.ac.uk/pdbsum/8frd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8frd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8frd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8frd OCA], [https://pdbe.org/8frd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8frd RCSB], [https://www.ebi.ac.uk/pdbsum/8frd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8frd ProSAT]</span></td></tr>
	</table>		</table>

OCA at 09:53, 15 March 2023

OCA — Wed, 15 Mar 2023 09:53:24 GMT

←Older revision		Revision as of 09:53, 15 March 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 8frd is ON HOLD~~	+	==Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH 5.25==
-		+	<StructureSection load='8frd' size='340' side='right'caption='[[8frd]], [[Resolution\|resolution]] 1.68Å' scene=''>
-	~~Authors: Diaz, R.E., Fraser, J.S.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8frd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FRD FirstGlance]. <br>
-	~~Description:~~ Mouse acidic mammalian chitinase, catalytic domain in complex with N,N''-diacetylchitobiose at pH 5.25	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8frd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8frd OCA], [https://pdbe.org/8frd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8frd RCSB], [https://www.ebi.ac.uk/pdbsum/8frd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8frd ProSAT]</span></td></tr>
-	[[Category: Diaz~~, R.E~~]]	+	</table>
-	[[Category: Fraser~~, J.S~~]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/CHIA_MOUSE CHIA_MOUSE] Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. Presence in saliva and gastric juice suggests a function as a digestive enzyme.<ref>PMID:11085997</ref> <ref>PMID:12133911</ref> <ref>PMID:15192232</ref> <ref>PMID:19076793</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Mus musculus]]
		+	[[Category: Diaz RE]]
		+	[[Category: Fraser JS]]

OCA: Protected "8frd" [edit=sysop:move=sysop]

OCA — Wed, 18 Jan 2023 05:10:52 GMT

Protected "8frd" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:10, 18 January 2023

OCA: New page: '''Unreleased structure''' The entry 8frd is ON HOLD Authors: Diaz, R.E., Fraser, J.S. Description: Mouse acidic mammalian chitinase, catalytic domain in complex with N,N''-diacetylchi...

OCA — Wed, 18 Jan 2023 05:10:50 GMT

New page: '''Unreleased structure''' The entry 8frd is ON HOLD Authors: Diaz, R.E., Fraser, J.S. Description: Mouse acidic mammalian chitinase, catalytic domain in complex with N,N''-diacetylchi...

New page

'''Unreleased structure'''

The entry 8frd is ON HOLD

Authors: Diaz, R.E., Fraser, J.S.

Description: Mouse acidic mammalian chitinase, catalytic domain in complex with N,N''-diacetylchitobiose at pH 5.25
[[Category: Unreleased Structures]]
[[Category: Diaz, R.E]]
[[Category: Fraser, J.S]]