OCA at 11:25, 24 January 2024

OCA — Wed, 24 Jan 2024 11:25:35 GMT

←Older revision		Revision as of 11:25, 24 January 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8fw3 is ~~ON HOLD until Paper Publication~~	+	==MtrR from Neisseria gonorrhoeae bound to Testosterone==
-		+	<StructureSection load='8fw3' size='340' side='right'caption='[[8fw3]], [[Resolution\|resolution]] 2.22Å' scene=''>
-	~~Authors~~: ~~Hooks~~, G.H., ~~Brennan~~, R.G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8fw3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FW3 FirstGlance]. <br>
-	~~Description~~: ~~MtrR from Neisseria gonorrhoeae bound~~ to ~~Testosterone~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.22Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TES:TESTOSTERONE'>TES</scene></td></tr>
-	[[Category: Brennan~~, R.G~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fw3 OCA], [https://pdbe.org/8fw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fw3 RCSB], [https://www.ebi.ac.uk/pdbsum/8fw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fw3 ProSAT]</span></td></tr>
-	[[Category: Hooks~~, G.H~~]]	+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MTRR_NEIGO MTRR_NEIGO] Controls the permeability of the cell envelope to hydrophobic compounds such as antibiotics and detergents (PubMed:8196548). Represses transcription of the mtrCDE-encoded efflux pump by binding within the mtrCDE promoter (PubMed:9209024, PubMed:23221802). Also negatively regulates the expression of farR, by binding to its promoter region, leading indirectly to the positive regulation of expression of the farAB-encoded efflux pump (PubMed:14645274).<ref>PMID:14645274</ref> <ref>PMID:23221802</ref> <ref>PMID:8196548</ref> <ref>PMID:9209024</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Neisseria gonorrhoeae]]
		+	[[Category: Brennan RG]]
		+	[[Category: Hooks GH]]

OCA at 08:43, 15 February 2023

OCA — Wed, 15 Feb 2023 08:43:59 GMT

←Older revision		Revision as of 08:43, 15 February 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8fw3 is ON HOLD	+	The entry 8fw3 is ON HOLD until Paper Publication

	Authors: Hooks, G.H., Brennan, R.G.		Authors: Hooks, G.H., Brennan, R.G.

OCA: Protected "8fw3" [edit=sysop:move=sysop]

OCA — Wed, 01 Feb 2023 09:24:39 GMT

Protected "8fw3" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:24, 1 February 2023

OCA: New page: '''Unreleased structure''' The entry 8fw3 is ON HOLD Authors: Hooks, G.H., Brennan, R.G. Description: MtrR from Neisseria gonorrhoeae bound to Testosterone [[Category: Unreleased Struc...

OCA — Wed, 01 Feb 2023 09:24:37 GMT

New page: '''Unreleased structure''' The entry 8fw3 is ON HOLD Authors: Hooks, G.H., Brennan, R.G. Description: MtrR from Neisseria gonorrhoeae bound to Testosterone [[Category: Unreleased Struc...

New page

'''Unreleased structure'''

The entry 8fw3 is ON HOLD

Authors: Hooks, G.H., Brennan, R.G.

Description: MtrR from Neisseria gonorrhoeae bound to Testosterone
[[Category: Unreleased Structures]]
[[Category: Brennan, R.G]]
[[Category: Hooks, G.H]]

8fw3 - Revision history

OCA at 11:25, 24 January 2024

OCA at 08:43, 15 February 2023

OCA: Protected "8fw3" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8fw3 is ON HOLD Authors: Hooks, G.H., Brennan, R.G. Description: MtrR from Neisseria gonorrhoeae bound to Testosterone [[Category: Unreleased Struc...