OCA at 06:49, 8 February 2023

OCA — Wed, 08 Feb 2023 06:49:11 GMT

←Older revision		Revision as of 06:49, 8 February 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8fwk ~~is ON HOLD~~	+	==CryoEM structure of Human ABCB6 Transporter==
-		+	<StructureSection load='8fwk' size='340' side='right'caption='[[8fwk]], [[Resolution\|resolution]] 3.50Å' scene=''>
-	~~Authors~~: ~~Shaik~~, M.M., ~~Myasnikov~~, A.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8fwk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FWK FirstGlance]. <br>
-	~~Description~~: ~~CryoEM structure of Human~~ ABCB6 ~~Transporter~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fwk OCA], [https://pdbe.org/8fwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fwk RCSB], [https://www.ebi.ac.uk/pdbsum/8fwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fwk ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
-	[[Category: ~~Shaik, M.M~~]]	+	== Disease ==
-	[[Category: Myasnikov, A]]	+	[https://www.uniprot.org/uniprot/ABCB6_HUMAN ABCB6_HUMAN] Ocular coloboma;Dyschromatosis universalis;Colobomatous microphthalmia. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. ABCB6 mutations are involved in familial pseudohyperkalemia, a dominantly inherited condition characterized by increased serum potassium levels, measured in whole-blood specimens stored at or below room temperature. This condition is not accompanied by clinical symptoms or biological signs except for borderline abnormalities of red cell shape (PubMed:23180570).<ref>PMID:23180570</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ABCB6_HUMAN ABCB6_HUMAN] Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.<ref>PMID:10837493</ref> <ref>PMID:17006453</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Myasnikov A]]
		+	[[Category: Shaik MM]]

OCA: Protected "8fwk" [edit=sysop:move=sysop]

OCA — Wed, 01 Feb 2023 09:26:31 GMT

Protected "8fwk" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:26, 1 February 2023

OCA: New page: '''Unreleased structure''' The entry 8fwk is ON HOLD Authors: Shaik, M.M., Myasnikov, A. Description: CryoEM structure of Human ABCB6 Transporter Category: Unreleased Structures [[...

OCA — Wed, 01 Feb 2023 09:26:29 GMT

New page: '''Unreleased structure''' The entry 8fwk is ON HOLD Authors: Shaik, M.M., Myasnikov, A. Description: CryoEM structure of Human ABCB6 Transporter Category: Unreleased Structures [[...

New page

'''Unreleased structure'''

The entry 8fwk is ON HOLD

Authors: Shaik, M.M., Myasnikov, A.

Description: CryoEM structure of Human ABCB6 Transporter
[[Category: Unreleased Structures]]
[[Category: Shaik, M.M]]
[[Category: Myasnikov, A]]

8fwk - Revision history

OCA at 06:49, 8 February 2023

OCA: Protected "8fwk" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8fwk is ON HOLD Authors: Shaik, M.M., Myasnikov, A. Description: CryoEM structure of Human ABCB6 Transporter Category: Unreleased Structures [[...