8fxp - Revision history

OCA at 08:00, 6 December 2023

OCA — Wed, 06 Dec 2023 08:00:16 GMT

←Older revision		Revision as of 08:00, 6 December 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8fxp is ~~ON HOLD until 2025~~-01-25	+	==Structure of capsid of Agrobacterium phage Milano==
		+	<StructureSection load='8fxp' size='340' side='right'caption='[[8fxp]], [[Resolution\|resolution]] 4.04Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8fxp]] is a 64 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_phage_Milano Agrobacterium phage Milano]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FXP FirstGlance]. <br>
		+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 4.04Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fxp OCA], [https://pdbe.org/8fxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fxp RCSB], [https://www.ebi.ac.uk/pdbsum/8fxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fxp ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A482MFR0_9CAUD A0A482MFR0_9CAUD]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Large gaps exist in our understanding of how bacteriophages, the most abundant biological entities on Earth, assemble and function. The structure of the "neck" region, where the DNA-filled capsid is connected to the host-recognizing tail remains poorly understood. We describe cryo-EM structures of the neck, the neck-capsid and neck-tail junctions, and capsid of the Agrobacterium phage Milano. The Milano neck 1 protein connects the 12-fold symmetrical neck to a 5-fold vertex of the icosahedral capsid. Comparison of Milano neck 1 homologs leads to four proposed classes, likely evolved from the simplest one in siphophages to more complex ones in myo- and podophages. Milano neck is surrounded by the atypical collar, which covalently crosslinks the tail sheath to neck 1. The Milano capsid is decorated with three types of proteins, a minor capsid protein (mCP) and two linking proteins crosslinking the mCP to the major capsid protein. The extensive network of disulfide bonds within and between neck, collar, capsid and tail provides an exceptional structural stability to Milano.

-	~~Authors: Sonani, R.R~~., ~~Wang, F.~~, Esteves, ~~N.C.~~, Kelly~~, R.J.~~, Sebastian, A., Kreutzberger~~, M.A.B.~~, Leiman~~, P.G.~~, Scharf, B.E.~~, Egelman, E~~.H.	+	Neck and capsid architecture of the robust Agrobacterium phage Milano.,Sonani RR, Esteves NC, Horton AA, Kelly RJ, Sebastian AL, Wang F, Kreutzberger MAB, Leiman PG, Scharf BE, Egelman EH Commun Biol. 2023 Sep 8;6(1):921. doi: 10.1038/s42003-023-05292-1. PMID:37684529<ref>PMID:37684529</ref>

-	~~Description: Structure~~ of ~~capsid~~ of Agrobacterium phage Milano	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Egelman~~, E.H~~]]	+	<div class="pdbe-citations 8fxp" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Scharf, B.E~~]]	+	== References ==
-	[[Category: Kelly~~, R.J~~]]	+	<references/>
-	[[Category: ~~Wang, F~~]]	+	__TOC__
-	[[Category: ~~Esteves, N.C~~]]	+	</StructureSection>
-	[[Category: ~~Sonani, R.R~~]]	+	[[Category: Agrobacterium phage Milano]]
-	[[Category: ~~Leiman, P.G~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Kreutzberger, M.A.B~~]]	+	[[Category: Egelman EH]]
-	[[Category: ~~Sebastian, A~~]]	+	[[Category: Esteves NC]]
		+	[[Category: Kelly RJ]]
		+	[[Category: Kreutzberger MAB]]
		+	[[Category: Leiman PG]]
		+	[[Category: Scharf BE]]
		+	[[Category: Sebastian A]]
		+	[[Category: Sonani RR]]
		+	[[Category: Wang F]]

OCA at 10:15, 22 February 2023

OCA — Wed, 22 Feb 2023 10:15:12 GMT

←Older revision		Revision as of 10:15, 22 February 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8fxp is ON HOLD	+	The entry 8fxp is ON HOLD until 2025-01-25

	Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelman, E.H.		Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelman, E.H.
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	Description: Structure of capsid of Agrobacterium phage Milano		Description: Structure of capsid of Agrobacterium phage Milano
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Sonani, R.R]]
	[[Category: Egelman, E.H]]		[[Category: Egelman, E.H]]
-	[[Category: Kelly, R.J]]
-	[[Category: Leiman, P.G]]
	[[Category: Scharf, B.E]]		[[Category: Scharf, B.E]]
-	[[Category: ~~Esteves~~, N.C]]	+	[[Category: Kelly, R.J]]
	[[Category: Wang, F]]		[[Category: Wang, F]]
		+	[[Category: Esteves, N.C]]
		+	[[Category: Sonani, R.R]]
		+	[[Category: Leiman, P.G]]
	[[Category: Kreutzberger, M.A.B]]		[[Category: Kreutzberger, M.A.B]]
	[[Category: Sebastian, A]]		[[Category: Sebastian, A]]

OCA: Protected "8fxp" [edit=sysop:move=sysop]

OCA — Wed, 01 Feb 2023 09:30:17 GMT

Protected "8fxp" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:30, 1 February 2023

OCA: New page: '''Unreleased structure''' The entry 8fxp is ON HOLD Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelma...

OCA — Wed, 01 Feb 2023 09:30:14 GMT

New page: '''Unreleased structure''' The entry 8fxp is ON HOLD Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelma...

New page

'''Unreleased structure'''

The entry 8fxp is ON HOLD

Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelman, E.H.

Description: Structure of capsid of Agrobacterium phage Milano
[[Category: Unreleased Structures]]
[[Category: Sonani, R.R]]
[[Category: Egelman, E.H]]
[[Category: Kelly, R.J]]
[[Category: Leiman, P.G]]
[[Category: Scharf, B.E]]
[[Category: Esteves, N.C]]
[[Category: Wang, F]]
[[Category: Kreutzberger, M.A.B]]
[[Category: Sebastian, A]]